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Receptors and Other Targets for Toxic Substances, P.L. Chambers; E. Cholnoky; C. Chambers


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Автор: P.L. Chambers; E. Cholnoky; C. Chambers
Название:  Receptors and Other Targets for Toxic Substances
ISBN: 9783540136705
Издательство: Springer
Классификация:


ISBN-10: 3540136703
Обложка/Формат: Paperback
Страницы: 520
Вес: 0.84 кг.
Дата издания: 01.12.1985
Серия: Archives of Toxicology
Язык: English
Размер: 244 x 170 x 27
Основная тема: Biomedicine
Подзаголовок: Proceedings of the European Society of Toxicology, Meeting Held in Budapest, June 11–14, 1984
Ссылка на Издательство: Link
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Поставляется из: Германии


Transporters as Targets for Drugs

Автор: Susan Napier; Matilda Bingham
Название: Transporters as Targets for Drugs
ISBN: 3642099696 ISBN-13(EAN): 9783642099694
Издательство: Springer
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Цена: 34799.00 р.
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Описание: In each volume of Transporters as Targets for Drugs an overview chapter introduces the newcomer to the topic covered. The series covers hot topics of frontier research summarized by reputed scientists in the field.

Sigma Receptors: Their Role in Disease and as Therapeutic Targets

Автор: Sylvia B. Smith; Tsung-Ping Su
Название: Sigma Receptors: Their Role in Disease and as Therapeutic Targets
ISBN: 3319501720 ISBN-13(EAN): 9783319501727
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets.

Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases

Автор: Marek Los; Spencer B. Gibson
Название: Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
ISBN: 1489996893 ISBN-13(EAN): 9781489996893
Издательство: Springer
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Цена: 23757.00 р.
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Описание: As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer.

Phosphodiesterases as Drug Targets

Автор: Sharron H. Francis; Marco Conti; Miles D. Houslay
Название: Phosphodiesterases as Drug Targets
ISBN: 3642269451 ISBN-13(EAN): 9783642269455
Издательство: Springer
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Цена: 52243.00 р.
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Описание: Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Along with its coverage of fresh and emerging ideas in this key field, the book examines all the major concepts related to the design and use of PDE inhibitors.

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

Автор: Bharat B. Aggarwal; Young-Joon Surh; S. Shishodia
Название: The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease
ISBN: 038746400X ISBN-13(EAN): 9780387464008
Издательство: Springer
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Цена: 32652.00 р.
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Описание: Curcumin is derived from the root of the plant Curcuma longa (also called turmeric) and its medicinal uses have been described for over 5000 years. This monograph deals with this subject.

Histamine Receptors as Drug Targets

Автор: Ekaterini Tiligada; Madeleine Ennis
Название: Histamine Receptors as Drug Targets
ISBN: 1493968416 ISBN-13(EAN): 9781493968411
Издательство: Springer
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Цена: 27950.00 р.
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Описание:

1. Methodologies to Identify and Analyze Genetic Polymorphisms for Human Histamine Receptors

Stephany Micallef and Astrid Sasse

2. Development, Characterization, and Validation of Anti-Human H3 Receptor Isoform-Specific Antibodies

Fiona C. Shenton, Natasha Lethbridge, and Paul L. Chazot

3. Approaches to Recombinant Histamine H3/H4 Receptor Expression in Mammalian Cells

Tadeusz Karcz, Urszula Cichoń, and Katarzyna Kiec-Kononowicz

4. Histamine H2 Receptor Biased Signaling Methods

Natalia Fernбndez, Carina Shayo, Carlos Davio, and Federico Monczor

5. Ligand-Binding Kinetics on Histamine Receptors

Reggie Bosma, Tamara A.M. Mocking, Rob Leurs, and Henry F. Vischer

6. Methods to Study the Molecular Pharmacology of the Histamine H4 Receptor

Elйonore W.E. Verweij, Rob Leurs, and Henry F. Vischer

7. Chemiluminescence: A Sensitive Method for Detecting the Effects of Histamine Receptor Agonists/Antagonists on Neutrophil Oxidative Burst

Ondřej Vasнček, Tomбs Perečko, Viera Jančinovб, Silvia Pazourekovб, Radomнr Nosбľ, and Milan Čнz

8. Techniques Used in Pharmacological Evaluation of Histamine H4 Receptor Function on Native Human Eosinophils

Marek Grosicki and Katarzyna Kiec-Kononowicz

9. Assessment of the Efficacy of Histamine Receptor Antagonists in Murine Models of Atopic Dermatitis

Kristine Ro bach, Hanna Kцchling, Tomoki Fukuyama, Jenny Wilzopolski, Manfred Kietzmann, and Wolfgang Bдumer

10. Methodological Approaches to Study Histamine Pharmacology in the Kidney: From Cell Culture and Cell Imaging to Functional Assays and Electron Microscopy

Alessandro Pini, Eleonora Veglia, Cristina Grange, and Arianna Carolina Rosa

11. Histamine and the Kidney: In Vivo Animal Models

Alessandro Pini, Eleonora Veglia, and Arianna Carolina Rosa

12. Methodological Approaches to Investigate the Effects of Histamine Receptor Targeting Compounds in Preclinical Models of Breast Cancer

Diego J. Martinel Lamas, Melisa B. Nicoud, Helena Sterle, Graciela P. Cricco, Gabriela A. Martin, Graciela A. Cremaschi, Hubert G. Schwelberger, Elena S. Rivera, and Vanina A Medina

13. Evaluation of Histidine Decarboxylase (HDC) Activity and Human Histamine Receptor 3 (H3R) and HDC mRNA Levels

Carlos Acosta-Andrade, Josй L Urdiales, Ignacio Fajardo, and Francisca Sбnchez-Jimйnez

14. Cerebrospinal Fluid Markers in Neuroinflammation: The Paradigm of Optic Neuritis

Dimitrios P. Besinis and Maria C. Anagnostouli

Membrane Receptors and Enzymes as Targets of Insecticidal Action

Автор: J. Marshall Clark; Fumio Matsumura
Название: Membrane Receptors and Enzymes as Targets of Insecticidal Action
ISBN: 1468451154 ISBN-13(EAN): 9781468451153
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The volume which resulted from this symposium, -Membranes Receptors and Enzymes as Targets of Insecticidal Action-, details a number of bio- chemical modes of action of insecticides on the insect nervous system.

Checkpoint Controls and Targets in Cancer Therapy

Автор: Siddik
Название: Checkpoint Controls and Targets in Cancer Therapy
ISBN: 1617796352 ISBN-13(EAN): 9781617796357
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Checkpoint regulation is critical in understanding cancer development and cancer therapy. This book builds upon existing concepts of checkpoints and aims to expand our understanding of the inner workings of the critical checkpoint machinery.

Therapeutic Targets of the TNF Superfamily

Автор: Iqbal S. Grewal
Название: Therapeutic Targets of the TNF Superfamily
ISBN: 1441927999 ISBN-13(EAN): 9781441927996
Издательство: Springer
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Цена: 26120.00 р.
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Описание: For two decades, TNF superfamily has been the most investigated area of basic medical research. This book offers a state-of-the-art account of that research, including the role of TNF superfamily members to fight cancer and autoimmune disease.


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