Risk Assessment in Chemical Carcinogenesis, Gotthard Schettler; Dietrich Schm?hl; Thomas Klenn
Автор: Trevor M. Penning Название: Chemical Carcinogenesis ISBN: 1617797294 ISBN-13(EAN): 9781617797293 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presenting the current advances in chemical carcinogenesis, this volume promotes the view that the chemical alteration of DNA is a route cause of many cancers. Topics include the multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action.
Автор: Yusaku Tagashira Название: P-450 and Chemical Carcinogenesis ISBN: 1468450328 ISBN-13(EAN): 9781468450323 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is one of a GANN Monograph on Cancer Research series and is based on a Japanese Cancer Association-sponsored symposium entitled "Multiplicity of Chemical Carcinogen-Activating Enzymes* with Particular Emphasis on Cytochrome P-450" which was held in Tokyo on November 21, 1983.
Автор: A. Kappas Название: Mechanisms of Environmental Mutagenesis-Carcinogenesis ISBN: 1461366984 ISBN-13(EAN): 9781461366980 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy.
Описание: Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importance of protein precursors maturation by the convertases in tumor progression, angiogenesis and metastasis. In each chapter, the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases is discussed. Also this book covers the role of some convertases in the clinical setting. The book will be of interest to basic researchers as well as clinicians. It will also interest those working in the cancer research area and the pharmaceutical industry, who are looking for new strategies in cancer therapy. Finally, this book is also a useful reference for researchers and clinicians pursuing research on growth factors, adhesion molecules, proteases and their implications in the processes of tumor progression, angiogenesis and metastasis.
Автор: Frederick F. Becker Название: Etiology: Chemical and Physical Carcinogenesis ISBN: 1461566002 ISBN-13(EAN): 9781461566007 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although great strides have been made toward those goals, as evidenced by a number of new chapters and the new information gathered into others, and although the achievement of those goals sometimes appears but a tantalizing experiment away, none have been achieved.
Автор: F.A. Beland; L.G. Cain; J.S. Felton; J.D. Groopman Название: Chemical Carcinogenesis and Mutagenesis I ISBN: 3642747779 ISBN-13(EAN): 9783642747779 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin- Madison.
Автор: R. Colin Garner; Jan Hradec Название: Biochemistry of Chemical Carcinogenesis ISBN: 1461278562 ISBN-13(EAN): 9781461278566 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The hepatocarcinogenicity of aflatoxin BI in rats, ducks and rainbow trout has been convincingly demonstrated (1). In contrast, adult mice appear to be resistant to the toxic and carcinogenic effects. Newborn and infant mice are more sensitive to the effects of different hepatocarcinogens (2,3) and also to AFB, which induced hepatomas in newborn C57BL/6 x C3H FI I mice (4). A singl dose model of aflatoxin hepatocarcinogenesis was tested in infant C57BL/6 mice. AFBI was administered i.p. on day 7 after birth and the following data were investigated: 1) Changes in the activities of microsomal cytochrome P-450 dependant enzymes and conjugating enzymes in the course of the 20-month-Iong aflatoxin hepa- tocarcinogenesis study. At intervals of 6,8,12,18 and 20 months a ter AFBI administration, the concentrations of cyt P-450 andb and the acti- 5 vities of NADPH-, NADH-cyt c reductase, AOH, ADM, EH and GST were deter- mined. 2) Effect of continually administered diethyldithiocarbamate on the course of aflatoxin carcinogenesis. MATERIALS AND METHODS Aflatoxin BI was prepared biosynthetically in our laboratory and was checked for purity chromatographically, spectrophotometrically and by NMR.
Автор: C.F. Arlett; Colin S. Cooper; Philip L. Grover; D. Название: Chemical Carcinogenesis and Mutagenesis II ISBN: 3642747809 ISBN-13(EAN): 9783642747809 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin- Madison.
Автор: H.K. M?ller-Hermelink; H.G. Neumann; W. Dekant Название: Risk and Progression Factors in Carcinogenesis ISBN: 364264385X ISBN-13(EAN): 9783642643859 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cellular transformation and carcinogenesis are considered a multistep process starting with DNA lesions and progressing through loss of cellular growth control and increase invasive and metastatic properties.
Автор: Oscar Sudilovsky; Henry C. Pitot; L.A. Liotta Название: Boundaries between Promotion and Progression during Carcinogenesis ISBN: 1468459961 ISBN-13(EAN): 9781468459968 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Based on a conference held in Cleveland, Ohio, September 28--30, 1988
Автор: A. Schimpl; Peter Bannasch Название: The Cytoplasm of Hepatocytes during Carcinogenesis ISBN: 3642884016 ISBN-13(EAN): 9783642884016 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Used in the proper dose, these carcinogens lead within a few months to the formation of multicentric hepatomas in practically 100 Ufo of the experimental animals, and are therefore a very useful tool for studies of the cytogenesis of cancer (see BUCHNER, 1961;
Автор: P. H?hn; E. Grundmann; E. Kunze; K. Nomura; C. Wit Название: Carcinogenesis ISBN: 3642672949 ISBN-13(EAN): 9783642672941 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Concepts on the Causal Genesis of Human Intestinal Tumors The action of chemical substances has a significant role in the genesis of human tumors. It is assumed that most human tumors are induced by exogenous chemical noxae (Schmahl, 1970;Heidelberger, 1975;
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