Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Автор: Sudhir Gupta; William E. Paul; Ralph Steinman Название: Mechanisms of Lymphocyte Activation and Immune Regulation X ISBN: 1441937005 ISBN-13(EAN): 9781441937001 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is edited by Dr. Sudhir Gupta, internationally recognized expert in Immunology, Professor of Medicine, Pathology, Microbiology and Molecular Genetics. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Автор: Sudhir Gupta; William E. Paul; Max D. Cooper; Elle Название: Mechanisms of Lymphocyte Activation and Immune Regulation III ISBN: 1468459457 ISBN-13(EAN): 9781468459456 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Third International Conference on Lymphocyte Activation and Immune Regulation, held in Newport Beach, California, February 16--18, 1990
Автор: Sudhir Gupta; Eugene Butcher; William E. Paul Название: Lymphocyte Activation and Immune Regulation IX ISBN: 1461352266 ISBN-13(EAN): 9781461352266 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Ninth International Conference on Lymphocyte Activation and Immune Regulation held on February 8-10, 2002 in Newport Beach, California, U.S.A
Описание: Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases.
Автор: Sudhir Gupta; William E. Paul; Anthony DeFranco; R Название: Mechanisms of Lymphocyte Activation and Immune Regulation V ISBN: 1489909893 ISBN-13(EAN): 9781489909893 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It includes a contemporary assessment of B cell antigen receptor structures, and discussion of the role of Ig-a/lg-B polypeptides in linking the antigen receptor to intracellular signal transduction pathways.
Автор: Sudhir Gupta; J. John Cohen Название: Mechanisms of Lymphocyte Activation and Immune Regulation VI ISBN: 1489902767 ISBN-13(EAN): 9781489902764 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding the basic mechanisms and genes regulating programmed cell death and apoptosis. In addition, defects in various genes regulating programmed cell death have been delineated in several experimental models of human diseases. This volume surveys various aspects of these rapidly developing areas of research in programmed cell death/apoptosis. This volume should be of interest to basic immunologists and molecular biologists. The volume begins with a historical perspective of cell death. The remainder of the volume is divided into four different parts. Part I deals with the signaling pathways in apoptosis, including cell cycle control of apoptosis, role of ceramide in apoptosis, role of antibody signaling, and biochemical regulation of apoptosis. The mechanisms for recognition of apoptotic lymphocytes by macrophages are also reviewed. Part II examines the role of various genes that regulate apoptosis, including the role ofFas, FasL, and other TNF family members in apoptosis and homeostatic regulation of immune response. Recently described splice variants and their influence on apoptosis are also reviewed, and the role of the members of the Bcl-2 family in apoptosis is discussed in detail. Part III reviews various aspects of apoptosis in B lymphocytes, including mechanisms that regulate apoptosis/survival of B lymphocytes and the regulation of Fas-mediated apoptosis in B lymphocytes.
Описание: It includes a model for the T cell receptor interaction with a complex of MHC plus antigen, structure of y c`i T cell receptor and their distinct isotypic forms, the role of zeta chain in the expression and structure of T cell receptors and its role in transmembrane signalling.
Автор: Sudhir Gupta; Thomas Waldmann Название: Mechanisms of Lymphocyte Activation and Immune Regulation IV ISBN: 1461365007 ISBN-13(EAN): 9781461365006 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent data suggest a role of interaction between plasma membrane molecules of activated T helper cells and B cells, B cells primed with plasma membrane of activated T helper cells and cytokines, and interaction between bone marrow stromal cells and B cell progenitors and precursors, in the B cell development, proliferation, and differentiation.
Описание: The immune system must maintain a balance between the deletion of harmful self-reactive B cells and the generation of a diverse rep- ertoire of B cells that has the ability to recognize an almost un- limited array of foreign antigens.
Описание: This volume provides a review of current research in the field of B cell development and differentiation with particular emphasis on signal transduction processes.
Описание: This volume reviews research in the field of B cell development and differentiation. The contents focus on the biochemical pathways regulating B cell biology and the role of signal transduction processes in regulating various aspects of B cell function, development and differentiation.
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