Inflammation II, Einar Ljunggren; Carl Erich Alken; Roddy Campbell

Автор: Nathalie Vergnolle; Michel Chignard
Название: Proteases and Their Receptors in Inflammation
ISBN: 3034803427 ISBN-13(EAN): 9783034803427
Издательство: Springer
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Цена: 26120.00 р.
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Описание:

Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response.

This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).

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Автор: Randall E. Harris
Название: Inflammation in the Pathogenesis of Chronic Diseases
ISBN: 9048174295 ISBN-13(EAN): 9789048174294
Издательство: Springer
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Цена: 34799.00 р.
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Описание: In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors.

Автор: Andreas Radbruch; Peter E. Lipsky
Название: Current Concepts in Autoimmunity and Chronic Inflammation
ISBN: 364206745X ISBN-13(EAN): 9783642067457
Издательство: Springer
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Цена: 32004.00 р.
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Описание: In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions.

Автор: Lane
Название: Central Nervous System Diseases and Inflammation
ISBN: 0387738932 ISBN-13(EAN): 9780387738932
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Focusing on inflammatory CNS disease, this book explores how chemokines affect disease. It contains four sections which revolve around areas of interest within the field of neuroimmunology, virology, pharmacology and disease.

Название: Smoking and Lung Inflammation
ISBN: 1461473500 ISBN-13(EAN): 9781461473503
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book focuses on both basic and clinical research on COPD, and the inflammatory mechanisms that function in these diseases. It includes knowledge gained from translational research conducted through clinical trials at several medical schools in the US.

Автор: Winkler
Название: Apoptosis and Inflammation.1999
ISBN: 3764357959 ISBN-13(EAN): 9783764357955
Издательство: Springer
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Цена: 30187.00 р.
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Описание: Apoptosis is a form of cell death that occurs in a controlled manner and is generally noninflammatory in nature. Apoptosis, or programmed cell death, implies a cell death that is part of a normal physiological process of pruning of unneeded cells. However, many disease conditions utilize apoptosis for pathological ends, resulting in inappropriate cell death and tissue destruction. This book starts with an introduction that reviews the general characteristics of apoptosis, its regulation and its role in physiology and disease. Next, the book focuses on three areas as they relate to inflammatory cells and diseases. The first area consists of chapters on signals for apoptosis important to inflammatory cells, namely growth factors and arachidonic acid metabolism. The next area that the book focuses on are effects at the cellular level, on cell survival versus cell death and signals critical for cell function in both normal and disease states. These topics are covered in chapters on lymphocytes, granulocytes, chondrocytes and keratinocytes. The last area that the book focuses on are events at the level of tissue and disease, looking at the evidence for altered apoptosis and/or apoptotic processes in immune and inflammatory diseases. These topics are covered in chapters on rheumatoid arthritis, osteoarthritis, lupus, psoriasis and renal disease. Together, these chapters will provide the reader with the latest insight in the role of apoptosis in inflammatory cells and diseases. This book starts with an introduction that reviews the general characteristics of apoptosis, its regulation and its role in physiology and disease. Next, the book focuses on three areas as they relate to inflammatory cells and diseases. The first area consists of chapters on signals for apoptosis important to inflammatory cells, namely growth factors and arachidonic acid metabolism. The next area that the book focuses on are effects at the cellular level, on cell survival versus cell death and signals critical for cell function in both normal and disease states. These topics are covered in chapters on lymphocytes, granulocytes, chondrocytes and keratinocytes. The last area that the book focuses on are events at the level of tissue and disease, looking at the evidence for altered apoptosis and/or apoptotic processes in immune and inflammatory diseases. These topics are covered in chapters on rheumatoid arthritis, osteoarthritis, lupus, psoriasis and renal disease. Together, these chapters will provide the reader with the latest insight in the role of apoptosis in inflammatory cells and diseases.