Sepsis and Organ Dysfunction, A.E. Baue; G. Berlot; A. Gullo; J.L. Vincent

Автор: Maurice Lamy; Lambert G. Thijs
Название: Mediators of Sepsis
ISBN: 364284829X ISBN-13(EAN): 9783642848292
Издательство: Springer
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Описание: This volume contains contributions by well-known scientistsand clinicians in the fields of microbiology, infectiousdiseases, physiology, internal medicine, surgery,anaesthesiology, and intensive care medicine.

Автор: Jordi Rello; Jeffrey Lipman; Thiago Lisboa
Название: Sepsis Management
ISBN: 3662519402 ISBN-13(EAN): 9783662519400
Издательство: Springer
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Описание: This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

Автор: Evans
Название: Mechanisms of Organ Dysfunction in Critical Illness. 2002
ISBN: 3540421939 ISBN-13(EAN): 9783540421931
Издательство: Springer
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Описание: Whereas a great deal has been learned during the past quarter century about the inflammatory processes associated with sepsis (and other related conditions, such as ischemia/reperfusion injury), our understanding is far less developed with respect to the pathophysiological events that lead to organ dysfunction under these conditions.

Автор: J.L. Rombeau; J. Takala
Название: Gut Dysfunction in Critical Illness
ISBN: 3642802265 ISBN-13(EAN): 9783642802263
Издательство: Springer
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Описание: Dysfunction of the gastrointestinal tract in critically ill patients has recently become a focus of intensive research. Options for monitoring and treating gut dysfunction in critically ill patients are rapidly evolving.

Автор: Rello J.
Название: Sepsis Management
ISBN: 3642035183 ISBN-13(EAN): 9783642035180
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

Автор: G?nther Schlag; Heinz Redl; Daniel Traber
Название: Shock, Sepsis, and Organ Failure
ISBN: 3642645135 ISBN-13(EAN): 9783642645136
Издательство: Springer
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Описание: A report on new findings involving the brain in traumatic and septic shock, and after brain injury. It also includes the latest results of clinical and experimental pathophysiology in inflammatory processes after traumatic brain injury and the therapeutic effects of hypertonic fluid therapy.

Автор: Jean-Louis Vincent; Jean Carlet; Steven M. Opal
Название: The Sepsis Text
ISBN: 1475783345 ISBN-13(EAN): 9781475783346
Издательство: Springer
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Описание: The contributing authors to this book have spearheaded much of this research and the Editors have endeavored to create a textbook that is comprehensive in nature while maintaining a specific focus upon the multitude of work that constitutes the spectrum of sepsis research including: pathophysiology;

Автор: Konrad Reinhart; Klaus Eyrich; Charles Sprung
Название: Sepsis
ISBN: 3642850383 ISBN-13(EAN): 9783642850387
Издательство: Springer
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Описание: Sepsis is still the leading cause of death in surgical and general intensive care units. Although our knowledge of this complex syndrome has increased in recent years, it is still far from com- plete. New therapeutic approaches have been developed. Some did not fullfill the high expectations for their use in clinical prac- tice; others are still under clinical evaluation. is the aim of this monograph to offer basic information on the It etiology, definition, pathophysiology, prevention and therapy of sepsis and septic shock to both the clinician and the scientist. We believe that it presents an extensive overview that may help the clinician to better understand and treat sepsis and septic shock. We also hope that this work will give some directions for future research both in the clinical field as well as the laboratory. Jena, Berlin, Jerusalem, K.Reinhart February 1994 K.Eyrich C.Sprung TableofContents I.Definition/Prognosis Sepsis and Septic Shock: Update on Definitions (Jo-L.Vincent) 0 0 0 0 0 0 0 0 0 0 0 0 -------- 3 Clinical Manifestations and Prognostic Indicators in Sepsis (R.C.Bone) ... 0 - - - - - - - - - - - - - - - - - - - 16 What Determines Prognosis in Sepsis? Evidence for a Comprehensive Individual Patient Risk Assessment Approach to the Design and Analysis of Clinical Trials (W.A.Knaus, D.P.Wagner, F.E.Harrell, Jr.

Автор: M.P. Fink; D. Payen
Название: Role of Nitric Oxide in Sepsis and ARDS
ISBN: 3642799221 ISBN-13(EAN): 9783642799228
Издательство: Springer
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Описание: Nitric Oxide (NO) is a free radical, a gas, and a pluripotent product of mammalian cells. An internationally recognized group of scientists and clinicians have contributed chapters dealing with cutting-edge science and practical clinical strategies.

Автор: K. Reinhart; K. Eyrich
Название: Sepsis
ISBN: 3642830854 ISBN-13(EAN): 9783642830853
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Описание: Despite the progress that has been made in intensive care medicine, sepsis and septic shock are still accompanied by a high mortality rate. This monograph contains contributions by well-known scientists and clinicians in the fields of hygienics, microbiology, infectious diseases, physiology, surgery and intensive care medicine.

Автор: W.J. Sibbald; Jean-Louis Vincent
Название: Clinical Trials for the Treatment of Sepsis
ISBN: 364279226X ISBN-13(EAN): 9783642792267
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Описание: Sepsis and Innovative Treatment: The Odyssey R. C. Bone The Odyssey by Homer, dates back to the 8th century, B. C. 1]. It is a great epic adventure of Odysseus's dramatic journey from Troy back home to Ithaca. Odysseus survives the ordeals of this journey and returns with new powers and insights. The study of the pathogenesis and treatment of sepsis has also been an odys- sey. I feel we will return from this odyssey with new insights and treatments. However, as with Odysseus, this will occur only after considerable struggle. In the 1980s we had a rather simplistic view of sepsis. It was a highly lethal complication caused by infection and often charac- terized by shock and multi-organ failure. Our knowledge of the inflammatory responses associated with sepsis was embryonic compared to today. The inflammatory response was often treat- ment with mega-dose corticosteroids along with fluid resuscita- tion, vasopressors and antibiotics. Because of the paucity of mul- ti-center controlled trials documenting the risk/benefit ratio of the treatment of sepsis with corticosteroids, two large multi-cen- ter controlled trials were organized to evaluate the role of corti- costeroids in sepsis 2, 3]. Because animal models showed bene- fits of corticosteroids only with pre-treatment or early treatment, a definition of sepsis was used that did not require positive cul- ture documentation or septic shock to be included in the studied population.

Автор: G?nther Schlag; Heinz Redl
Название: Pathophysiology of Shock, Sepsis, and Organ Failure
ISBN: 3642767389 ISBN-13(EAN): 9783642767388
Издательство: Springer
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Описание: In this book current knowledge of the pathophysiology of shock, sepsis and multi organ failure is presented. Therapy must proceed from profound knowledge of the multi variant physiological events in order to influence shock, sepsis and organ failure.