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Clinical Trials for the Treatment of Sepsis, W.J. Sibbald; Jean-Louis Vincent


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Автор: W.J. Sibbald; Jean-Louis Vincent
Название:  Clinical Trials for the Treatment of Sepsis
ISBN: 9783642792267
Издательство: Springer
Классификация:




ISBN-10: 364279226X
Обложка/Формат: Paperback
Страницы: 406
Вес: 0.62 кг.
Дата издания: 22.11.2011
Серия: Update in Intensive Care and Emergency Medicine
Язык: English
Размер: 234 x 156 x 23
Основная тема: Medicine & Public Health
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Sepsis and Innovative Treatment: The Odyssey R. C. Bone The Odyssey by Homer, dates back to the 8th century, B. C. 1]. It is a great epic adventure of Odysseuss dramatic journey from Troy back home to Ithaca. Odysseus survives the ordeals of this journey and returns with new powers and insights. The study of the pathogenesis and treatment of sepsis has also been an odys- sey. I feel we will return from this odyssey with new insights and treatments. However, as with Odysseus, this will occur only after considerable struggle. In the 1980s we had a rather simplistic view of sepsis. It was a highly lethal complication caused by infection and often charac- terized by shock and multi-organ failure. Our knowledge of the inflammatory responses associated with sepsis was embryonic compared to today. The inflammatory response was often treat- ment with mega-dose corticosteroids along with fluid resuscita- tion, vasopressors and antibiotics. Because of the paucity of mul- ti-center controlled trials documenting the risk/benefit ratio of the treatment of sepsis with corticosteroids, two large multi-cen- ter controlled trials were organized to evaluate the role of corti- costeroids in sepsis 2, 3]. Because animal models showed bene- fits of corticosteroids only with pre-treatment or early treatment, a definition of sepsis was used that did not require positive cul- ture documentation or septic shock to be included in the studied population.


Sepsis

Автор: Nicholas S. Ward; Mitchell M. Levy
Название: Sepsis
ISBN: 3319484680 ISBN-13(EAN): 9783319484686
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis.

The Sepsis Text

Автор: Vincent Jean-Louis, Carlet Jean, Opal Steven M.
Название: The Sepsis Text
ISBN: 079237620X ISBN-13(EAN): 9780792376200
Издательство: Springer
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Цена: 32142.00 р.
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Описание: This textbook is written at the dawn of a new era in the management of sepsis. Recent achievements in the clinical management of septic shock are the culmination of decades of basic and applied research by innovative researchers and clinical investigators worldwide. The contributing authors to this book have spearheaded much of this research and the Editors have endeavored to create a textbook that is comprehensive in nature while maintaining a specific focus upon the multitude of work that constitutes the spectrum of sepsis research including: pathophysiology; monitoring systems; general support; microbial aspects; complications; and anti-sepsis therapies.

Management of Sepsis: the PIRO Approach

Автор: Jordi Rello; Emili D?az; Alejandro Rodr?guez (Eds.
Название: Management of Sepsis: the PIRO Approach
ISBN: 3642004784 ISBN-13(EAN): 9783642004780
Издательство: Springer
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Цена: 9776.00 р.
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Описание: Sepsis is a very important public health problem. It is widely acknowledged that the severe inflammatory response syndrome/severe sepsis paradigm fails to stratify sepsis patients adequately. This book reviews in how sepsis should be managed on the basis of a fresh approach to staging.

Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery.2007

Автор: AbrahamAbraham
Название: Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery.2007
ISBN: 3540301585 ISBN-13(EAN): 9783540301585
Издательство: Springer
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Цена: 16769.00 р.
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Описание: There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis.

Management of Sepsis: the PIRO Approach

Автор: Rello
Название: Management of Sepsis: the PIRO Approach
ISBN: 3642101488 ISBN-13(EAN): 9783642101489
Издательство: Springer
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Цена: 11179.00 р.
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Описание: Sepsis is a very significant public health problem. This book reviews in detail how sepsis should be managed on the basis of a novel approach to staging. The book clearly explains the advantages of the PIRO approach in different settings.

Sepsis Management

Автор: Jordi Rello; Jeffrey Lipman; Thiago Lisboa
Название: Sepsis Management
ISBN: 3662519402 ISBN-13(EAN): 9783662519400
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

Evolving Concepts in Sepsis and Septic Shock

Автор: Peter Q. Eichacker; J?r?me Pugin
Название: Evolving Concepts in Sepsis and Septic Shock
ISBN: 0792372352 ISBN-13(EAN): 9780792372356
Издательство: Springer
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Цена: 30606.00 р.
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Sepsis and Organ Dysfunction

Автор: A.E. Baue; G. Berlot; A. Gullo; J.L. Vincent
Название: Sepsis and Organ Dysfunction
ISBN: 8847000521 ISBN-13(EAN): 9788847000520
Издательство: Springer
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Цена: 12157.00 р.
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Описание: A Tribute to Roger Bone

Sepsis and Organ Dysfunction

Автор: A.E. Baue; G. Berlot; A. Gullo; J.-L. Vincent
Название: Sepsis and Organ Dysfunction
ISBN: 8847000963 ISBN-13(EAN): 9788847000964
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Progression of the sepsis-MODS syndrome is tied to: the severity and location of the lesion; the patient`s age; the remaining functional reserve; and the presence of mediatory which may be stimulatory, inhibitory or both. This overview is aimed at anaesthesiologists and doctors.

Sepsis and Organ Dysfunction

Автор: A.E. Baue; G. Berlot; A. Gullo; J.-L. Vincent
Название: Sepsis and Organ Dysfunction
ISBN: 8847001781 ISBN-13(EAN): 9788847001787
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Even if in the last years more information on sepsis and new treatments has become available, mortality rate is however high. Another major problem is the consequent organ failure, which grows in a sequential way and in relation with the lesion gravity and the functional reserves of the patient.

Sepsis

Автор: K. Reinhart; K. Eyrich
Название: Sepsis
ISBN: 3642830854 ISBN-13(EAN): 9783642830853
Издательство: Springer
Рейтинг:
Цена: 15372.00 р.
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Описание: Despite the progress that has been made in intensive care medicine, sepsis and septic shock are still accompanied by a high mortality rate. This monograph contains contributions by well-known scientists and clinicians in the fields of hygienics, microbiology, infectious diseases, physiology, surgery and intensive care medicine.

Sepsis Management

Автор: Rello J.
Название: Sepsis Management
ISBN: 3642035183 ISBN-13(EAN): 9783642035180
Издательство: Springer
Рейтинг:
Цена: 16769.00 р.
Наличие на складе: Поставка под заказ.

Описание: This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.


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