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Protein-Protein Interactions as New Drug Targets, Enno Klussmann; John Scott


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Автор: Enno Klussmann; John Scott
Название:  Protein-Protein Interactions as New Drug Targets
ISBN: 9783642091940
Издательство: Springer
Классификация:




ISBN-10: 3642091946
Обложка/Формат: Paperback
Страницы: 512
Вес: 0.73 кг.
Дата издания: 19.10.2010
Серия: Handbook of Experimental Pharmacology
Язык: English
Размер: 234 x 156 x 27
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book covers therapeutically relevant protein-protein interactions, focusing on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the field are included.


Photonics : linear and nonlinear interactions of laser light and matter

Автор: Menzel
Название: Photonics : linear and nonlinear interactions of laser light and matter
ISBN: 3540231609 ISBN-13(EAN): 9783540231608
Издательство: Springer
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Цена: 18167.00 р.
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Описание: The definition of "photonics" has been broadened in recent years to include nonlinear and quantum optics, today usually based on laser light. This book covers the fundamental properties of photon and light beams, both experimentally and theoretically. It covers the essentials of linear interactions and most of the nonlinear interactions between light and matter in both the transparent and absorbing cases. It also provides a basic knowledge of modern lasers, as well as the principles of nonlinear optical spectroscopy. It is self-consistent and enriched by a large number of calculated illustrations, examples, and descriptive tables. Graduate students in physics and electrical engineering, as well as other sciences, will find this book a thorough introduction to the field, while for lecturers and scientists it offers a rich source of useful information and a ready-to-hand reference. About 4000 references open access to original literature.The second edition is completely revised and enlarged. 

Phosphodiesterases as Drug Targets

Автор: Sharron H. Francis; Marco Conti; Miles D. Houslay
Название: Phosphodiesterases as Drug Targets
ISBN: 3642269451 ISBN-13(EAN): 9783642269455
Издательство: Springer
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Цена: 52243.00 р.
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Описание: Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Along with its coverage of fresh and emerging ideas in this key field, the book examines all the major concepts related to the design and use of PDE inhibitors.

Histamine Receptors as Drug Targets

Автор: Ekaterini Tiligada; Madeleine Ennis
Название: Histamine Receptors as Drug Targets
ISBN: 1493968416 ISBN-13(EAN): 9781493968411
Издательство: Springer
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Цена: 27950.00 р.
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Описание:

1. Methodologies to Identify and Analyze Genetic Polymorphisms for Human Histamine Receptors

Stephany Micallef and Astrid Sasse

2. Development, Characterization, and Validation of Anti-Human H3 Receptor Isoform-Specific Antibodies

Fiona C. Shenton, Natasha Lethbridge, and Paul L. Chazot

3. Approaches to Recombinant Histamine H3/H4 Receptor Expression in Mammalian Cells

Tadeusz Karcz, Urszula Cichoń, and Katarzyna Kiec-Kononowicz

4. Histamine H2 Receptor Biased Signaling Methods

Natalia Fernбndez, Carina Shayo, Carlos Davio, and Federico Monczor

5. Ligand-Binding Kinetics on Histamine Receptors

Reggie Bosma, Tamara A.M. Mocking, Rob Leurs, and Henry F. Vischer

6. Methods to Study the Molecular Pharmacology of the Histamine H4 Receptor

Elйonore W.E. Verweij, Rob Leurs, and Henry F. Vischer

7. Chemiluminescence: A Sensitive Method for Detecting the Effects of Histamine Receptor Agonists/Antagonists on Neutrophil Oxidative Burst

Ondřej Vasнček, Tomбs Perečko, Viera Jančinovб, Silvia Pazourekovб, Radomнr Nosбľ, and Milan Čнz

8. Techniques Used in Pharmacological Evaluation of Histamine H4 Receptor Function on Native Human Eosinophils

Marek Grosicki and Katarzyna Kiec-Kononowicz

9. Assessment of the Efficacy of Histamine Receptor Antagonists in Murine Models of Atopic Dermatitis

Kristine Ro bach, Hanna Kцchling, Tomoki Fukuyama, Jenny Wilzopolski, Manfred Kietzmann, and Wolfgang Bдumer

10. Methodological Approaches to Study Histamine Pharmacology in the Kidney: From Cell Culture and Cell Imaging to Functional Assays and Electron Microscopy

Alessandro Pini, Eleonora Veglia, Cristina Grange, and Arianna Carolina Rosa

11. Histamine and the Kidney: In Vivo Animal Models

Alessandro Pini, Eleonora Veglia, and Arianna Carolina Rosa

12. Methodological Approaches to Investigate the Effects of Histamine Receptor Targeting Compounds in Preclinical Models of Breast Cancer

Diego J. Martinel Lamas, Melisa B. Nicoud, Helena Sterle, Graciela P. Cricco, Gabriela A. Martin, Graciela A. Cremaschi, Hubert G. Schwelberger, Elena S. Rivera, and Vanina A Medina

13. Evaluation of Histidine Decarboxylase (HDC) Activity and Human Histamine Receptor 3 (H3R) and HDC mRNA Levels

Carlos Acosta-Andrade, Josй L Urdiales, Ignacio Fajardo, and Francisca Sбnchez-Jimйnez

14. Cerebrospinal Fluid Markers in Neuroinflammation: The Paradigm of Optic Neuritis

Dimitrios P. Besinis and Maria C. Anagnostouli

Drug Development / Molecular Targets for GI Diseases

Автор: Gaginella Timothy S., Guglietta Antonio
Название: Drug Development / Molecular Targets for GI Diseases
ISBN: 0896035891 ISBN-13(EAN): 9780896035898
Издательство: Springer
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Цена: 20263.00 р.
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Описание: The application of molecular techniques to gastroenterology continues to yield important advances in the development of drugs to treat gastrointestinal disorders.

Novel Therapeutic Targets for Antiarrhythmic Drugs

Автор: Billman G.E.
Название: Novel Therapeutic Targets for Antiarrhythmic Drugs
ISBN: 0470261005 ISBN-13(EAN): 9780470261002
Издательство: Wiley
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Цена: 26286.00 р.
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Описание: This book provides a comprehensive overview of several promising novel drug targets and approaches against arrhythmias, with particular emphasis placed on malignant ventricular arrhythmias.

Bacterial Signal Transduction: Networks and Drug Targets

Автор: Ryutaro Utsumi
Название: Bacterial Signal Transduction: Networks and Drug Targets
ISBN: 1441927034 ISBN-13(EAN): 9781441927033
Издательство: Springer
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Цена: 32004.00 р.
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Описание: This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been unearthed.

Membrane Transporters as Drug Targets

Автор: Gordon L. Amidon; Wolfgang Sad?e
Название: Membrane Transporters as Drug Targets
ISBN: 147578631X ISBN-13(EAN): 9781475786316
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Because progress in the field of transporters has been extraordinary, this volume will focus on recent advances in our understanding of the structure, function, physiology, and molecular biology of membrane transporters. There will be an emphasis on transporters as molecular targets for drug delivery and disposition in the body.


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