Acceleration and Improvement of Protein Identification by Mass Spectrometry, Willy Vincent Bienvenut
Автор: John R. Chapman Название: Protein and Peptide Analysis by Mass Spectrometry ISBN: 1489940731 ISBN-13(EAN): 9781489940735 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The purpose of the preface is to explain the book's objectives and how to use it; give warnings, disclaimers, and the like.* The main objective of Protein and Peptide Analysis by Mass Spec trometry is quite straightforward—to present authoritative, up-to-date, and practical accounts of the use of mass spectrometry in the analysis of pep tides and proteins. How to use it? Every reader will have their own particular interests and will surely be drawn toward the chapters that cover these interests. Within the remaining chapters, however, techniques are described with analytical possibilities that such a reader can then only guess at. So, read the book fully. Again, as is customary in the Methods in Molecular Biology series, the chapter format (Introduction, Materials, Methods, and Notes) allows the authors to introduce the techniques, to explain their relevance and applicability, and, above all, to provide detail—detail that represents each author's accumulated experience and enables the reader to use and benefit from these methods. So, read the book fully, and read it diligently. Warnings and disclaimers: Mass spectrometry today offers the pro tein chemist ready access to a wealth of information that is otherwise avail able only with great difficulty, or perhaps not at all. With this goal in sight, any warnings and disclaimers will almost surely be ignored. So, a warning anyway; the use of mass spectrometry might be habit forming.
Автор: Wilkins Название: Identification of Microorganisms by Mass Spectrometry.2005 ISBN: 0471654426 ISBN-13(EAN): 9780471654421 Издательство: Wiley Рейтинг: Цена: 21376.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Identification of Microorganism by Mass Spectrometry teaches the reader how to use the latest techniques in mass spectrometry to identify the presence of microorganisms for biochemical, biomedical, pharmaceutical, and bioterror applications.
Описание: This book highlights current approaches and future trends in the use of mass spectrometry to characterize protein therapies. As one of the most frequently utilized analytical techniques in pharmaceutical research and development, mass spectrometry has been widely used in the characterization of protein therapeutics due to its analytical sensitivity, selectivity, and specificity. This book begins with an overview of mass spectrometry techniques as related to the analysis of protein therapeutics, structural identification strategies, quantitative approaches, followed by studies involving characterization of process related protein drug impurities/degradants, metabolites, higher order structures of protein therapeutics. Both general practitioners in pharmaceutical research and specialists in analytical sciences will benefit from this book that details step-by-step approaches and new strategies to solve challenging problems related to protein therapeutics research and development.
Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development
Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery
Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs, instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis
Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers for cancer, targeted MS approaches for biomarker validation, biomarker discovery, and regulatory perspectives
Brings together the most current advances in the mass spectrometry technology and related method in protein analysis
Автор: Pradip Kumar Ghosh Название: Introduction to Protein Mass Spectrometry ISBN: 012805123X ISBN-13(EAN): 9780128051238 Издательство: Elsevier Science Рейтинг: Цена: 15662.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: . Introduction to Protein Mass Spectrometry provides a comprehensive overview of this increasingly important, yet complex, analytical technique. Unlike many other methods which automatically yield an absolutely unique protein name as output, protein mass spectrometry generally requires a deduction of protein identity from determination of peptide fragmentation products. This book enables readers to both understand, and appreciate, how determinations about protein identity from mass spectrometric data are made. Coverage begins with the technical basics, including preparations, instruments, and spectrometric analysis of peptides and proteins, before exploring applied use in biological applications, bioinformatics, database, and software resources. . Citing the most recent and relevant work in the field of biological mass spectrometry, the book is written for researchers and scientists new to the field, but is also an ideal resource for those hoping to hone their analytical abilities.
Описание: This volume presents a review of the latest numerical techniques used to identify ligand binding and protein complexation sites. It offers a comparative analysis of models based on geometry versus those based on knowledge of the biological phenomenon.
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