Steroid Receptor Methods, Benjamin A. Lieberman

Автор: Lieberman Benjamin A.
Название: Steroid Receptor Methods / Protocols and Assays
ISBN: 0896037541 ISBN-13(EAN): 9780896037540
Издательство: Springer
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Цена: 21661.00 р.
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Описание: A distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA binding characteristics, hormone binding assays, and the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness.

Автор: Gabriella Castoria; Ferdinando Auricchio
Название: Steroid Receptors
ISBN: 1493948458 ISBN-13(EAN): 9781493948451
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Steroid Receptors: Methods and Protocols presents a selection of techniques that have been recently applied to the analysis of steroid receptors, powerful tools for the advancement of our understanding of both the mechanisms regulating gene transcription and the rapid signaling responses of tissues to signals.

Автор: Chaohong Liu
Название: B Cell Receptor Signaling
ISBN: 1493974734 ISBN-13(EAN): 9781493974733
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This volume looks the current advanced protocols used to study aspects of the B cell receptor (BCR).

Автор: Frans Tax; Birgit Kemmerling
Название: Receptor-like Kinases in Plants
ISBN: 3642447988 ISBN-13(EAN): 9783642447983
Издательство: Springer
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Цена: 32004.00 р.
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Описание: Revealed by sequencing projects, receptor kinases are the largest group of primary signal transducers in plants. Their abundance hints at an immense network that we have just begun to reveal. This volume focuses on their role, signaling paths, and regulation.

Автор: Alexander Sigalov
Название: Multichain Immune Recognition Receptor Signaling
ISBN: 1441918876 ISBN-13(EAN): 9781441918871
Издательство: Springer
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Цена: 32004.00 р.
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Описание: This book shows how the structural similarity of MIRRs determines the general principles underlying MIRR-mediated transmembrane signaling mechanisms. In so doing, it provides the basis for existing and future therapeutic strategies targeting MIRRs.

Автор: Cheryl S. Watson
Название: The Identities of Membrane Steroid Receptors
ISBN: 146135028X ISBN-13(EAN): 9781461350286
Издательство: Springer
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Цена: 13974.00 р.
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Описание: New experimental tools have been brought to bear on the topic of receptors for steroids which mediate non-genomic actions, and thus investigative activity and focus regarding this type of steroid receptor has recently increased significantly.

Автор: Gabriella Castoria; Ferdinando Auricchio
Название: Steroid Receptors
ISBN: 149391345X ISBN-13(EAN): 9781493913459
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Steroid Receptors: Methods and Protocols presents a selection of techniques that have been recently applied to the analysis of steroid receptors, powerful tools for the advancement of our understanding of both the mechanisms regulating gene transcription and the rapid signaling responses of tissues to signals. Research in this area has generated a wealth of data allowing the elucidation of steroid receptor mechanisms and improving the treatment of many endocrine disorders, above all cancers. Chapters cover methods to analyze gene transcription, chromatin and proteomic modifications, extra-nuclear signaling regulation, development of cell and animal models, and preparation of new antibodies. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Steroid Receptors: Methods and Protocols offers an updated view on a variety of modern methods that will hopefully contribute to improving our knowledge on the integration of steroid receptors in single or different functionally connected cellular contexts under a variety of physiological and pathological conditions, above all tumors.

Автор: A. Cato; H. Schaecke; K. Asadullah
Название: Recent Advances in Glucocorticoid Receptor Action
ISBN: 3662046628 ISBN-13(EAN): 9783662046623
Издательство: Springer
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Цена: 26122.00 р.
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Автор: Craig W. Stevens
Название: G Protein-Coupled Receptor Genetics
ISBN: 1627037780 ISBN-13(EAN): 9781627037785
Издательство: Springer
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Цена: 23757.00 р.
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Описание: G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field.