Pharmacogenomics, Federico Innocenti

Название: Pharmacogenomics
ISBN: 1588294404 ISBN-13(EAN): 9781588294401
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions.

Автор: Bertino Joseph S
Название: Pharmacogenomics an Introduction and Clinical Perspective
ISBN: 0071741690 ISBN-13(EAN): 9780071741699
Издательство: McGraw-Hill
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Цена: 13211.00 р.
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Описание: Offers a coverage of all need-to-know topics, from individual molecules to systemic diseases, this book also provides an examination of the latest technologies that are constantly reshaping the field. It also includes general pharmacogenomics and pharmacogenetics concepts, including geneticvariation in signal transduction and targets.