Protein Engineering, Caroline Koehrer; Uttam L. RajBhandary
Автор: Robert Lanza Название: Principles of Tissue Engineering, ISBN: 0123983584 ISBN-13(EAN): 9780123983589 Издательство: Elsevier Science Рейтинг: Цена: 19601.00 р. 28002.00-30% Наличие на складе: Есть (1 шт.) Описание: Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. . This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike.
Автор: Maciej Pietrzyk Название: Computational Materials Engineering ISBN: 0124167071 ISBN-13(EAN): 9780124167070 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Computational Materials Engineering: Achieving High Accuracy and Efficiency in Metals Processing Simulations describes the most common computer modeling and simulation techniques used in metals processing, from so-called "fast" models to more advanced multiscale models, also evaluating possible methods for improving computational accuracy and efficiency.
Beginning with a discussion of conventional fast models like internal variable models for flow stress and microstructure evolution, the book moves on to advanced multiscale models, such as the CAFE method, which give insights into the phenomena occurring in materials in lower dimensional scales.
The book then delves into the various methods that have been developed to deal with problems, including long computing times, lack of proof of the uniqueness of the solution, difficulties with convergence of numerical procedures, local minima in the objective function, and ill-posed problems. It then concludes with suggestions on how to improve accuracy and efficiency in computational materials modeling, and a best practices guide for selecting the best model for a particular application.
Presents the numerical approaches for high-accuracy calculations
Provides researchers with essential information on the methods capable of exact representation of microstructure morphology
Helpful to those working on model classification, computing costs, heterogeneous hardware, modeling efficiency, numerical algorithms, metamodeling, sensitivity analysis, inverse method, clusters, heterogeneous architectures, grid environments, finite element, flow stress, internal variable method, microstructure evolution, and more
Discusses several techniques to overcome modeling and simulation limitations, including distributed computing methods, (hyper) reduced-order-modeling techniques, regularization, statistical representation of material microstructure, and the Gaussian process
Covers both software and hardware capabilities in the area of improved computer efficiency and reduction of computing time
Автор: O. Jardetsky Название: Protein Structure and Engineering ISBN: 1468457470 ISBN-13(EAN): 9781468457476 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Uwe T. Bornscheuer; Matthias H?hne Название: Protein Engineering ISBN: 1493973649 ISBN-13(EAN): 9781493973644 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details basic and advanced protocols for both stages of protein engineering: the library design phase and the identification of improved variants by screening and selection.
Автор: Krishna Mohan Poluri; Khushboo Gulati Название: Protein Engineering Techniques ISBN: 9811027315 ISBN-13(EAN): 9789811027314 Издательство: Springer Рейтинг: Цена: 8384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This brief provides a broad overview of protein-engineering research, offering a glimpse of the most common experimental methods. It also presents various computational programs with applications that are widely used in directed evolution, computational and de novo protein design. Further, it sheds light on the advantages and pitfalls of existing methodologies and future perspectives of protein engineering techniques.
Автор: Ernst-Ludwig Winnacker; Robert Huber Название: Protein Structure and Protein Engineering ISBN: 3642741754 ISBN-13(EAN): 9783642741753 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Protein engineering has had considerable impact on basic and applied research in biochemistry and molecular biology. Protein engineering, perhaps more than any other methods of protein analysis and peptide synthesis, has shown that proteins are organic molecules governed by the universal laws of chemistry and physics.
Автор: Caroline Koehrer; Uttam L. RajBhandary Название: Protein Engineering ISBN: 3540709371 ISBN-13(EAN): 9783540709374 Издательство: Springer Рейтинг: Цена: 40389.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Providing the reader with an introduction to state-of the-art concepts and methods in the rapidly advancing field of protein engineering, this book will be of use to anyone interested in the study of proteins, in academia as well as in industry.
Описание: Now in its fifth edition, Hydraulics in Civil and Environmental Engineering combines thorough coverage of the basic principles of civil engineering hydraulics with wide-ranging treatment of practical, real-world applications. This classic text is carefully structured into two parts to address principles before moving on to more advanced topics. The first part focuses on fundamentals, including hydrostatics, hydrodynamics, pipe and open channel flow, wave theory, physical modeling, hydrology, and sediment transport. The second part illustrates the engineering applications of these fundamental principles to pipeline system design; hydraulic structures; and river, canal, and coastal engineering—including up-to-date environmental implications. A chapter on computational hydraulics demonstrates the application of computational simulation techniques to modern design in a variety of contexts. What’s New in This Edition Substantive revisions of the chapters on hydraulic machines, flood hydrology, and computational modeling New material added to the chapters on hydrostatics, principles of fluid flow, behavior of real fluids, open channel flow, pressure surge in pipelines, wave theory, sediment transport, river engineering, and coastal engineering The latest recommendations on climate change predictions, impacts, and adaptation measures Updated references Hydraulics in Civil and Environmental Engineering, Fifth Edition is an essential resource for students and practitioners of civil, environmental, and public health engineering and associated disciplines. It is comprehensive, fully illustrated, and contains many worked examples. Spreadsheets and useful links to other web pages are available on an accompanying website, and a solutions manual is available to lecturers.
Автор: MГјller Kristian, Arndt Katja Название: Protein Engineering Protocols ISBN: 1588290727 ISBN-13(EAN): 9781588290724 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Protein engineering is a fascinating mixture of molecular biology, protein structure analysis, computation, and biochemistry, with the goal of developing useful or valuable proteins. Divided into two sections, Protein Engineering Protocols reviews rational protein design strategies and directed evolutionary techniques, and their impact on protein engineering. The first section presents design and computational strategies for protein engineering focusing on designing a protein with desired properties, including examples covering a wide range of engineering techniques, such as protein-protein interactions, DNA binding, antibody mimics, and enzymatic activity. The second section on evolutionary techniques provides step-by-step instructions on library design and statistical assessment of library quality. New methods for DNA shuffling as well as different selection strategies are also presented.Following the successful Methods in Molecular Biologyв„ў series format, this volume provides a comprehensive guide to the methods used at every stage of the engineering process. By combining a thorough theoretical foundation with detailed protocols, Protein Engineering Protocols will be invaluable to all research workers in the area, from graduate students to senior investigators.
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