Experimental Models of Chronic Inflammatory Diseases, L.E. Glynn; H.D. Schlumberger
Автор: Gupta Название: Anti-inflammatory Nutraceuticals and Chronic Diseases ISBN: 3319413325 ISBN-13(EAN): 9783319413327 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in various chronic diseases. Food and Drug Administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. This means that there is enormous potential for dietary agents that can modulate inflammatory pathways in humans. Leading experts describe the latest research on the role of anti-inflammatory nutraceuticals in preventing and treating chronic diseases.
Описание: Controversy still exists regarding how early disease-modifying agents (DMA) should be commenced and whether all patients with relapsing-remitting MS should in fact be treated. With their novel, multifaceted approach to basic science, the authors of this book offer help to clinicians and hope to patients.
Автор: Yuti Chernajovsky; Paul D. Robbins Название: Gene Therapy for Autoimmune and Inflammatory Diseases ISBN: 3034803060 ISBN-13(EAN): 9783034803069 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text addresses the latest advances in viral and non-viral vectors as well as novel targets and methods for the treatment of autoimmune and inflammatory disease. Its main focus is on pre-clinical testing with up-to-date clinical trials.
Автор: Vollenhoven Ronald Van Название: Clinical Therapy Research in the Inflammatory Diseases ISBN: 9814656321 ISBN-13(EAN): 9789814656320 Издательство: World Scientific Publishing Рейтинг: Цена: 11246.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This unique textbook provides information on the dramatic advances taking place in the field of inflammatory (autoimmune) diseases and their therapies.
Описание: This practical collection examines methodologies originating from the benefits of genome-wide approaches to studying epigenetics, which has opened the emerging field of epigenomics. Focusing on the areas of cancer, inflammatory and autoimmune disorders, chapters discuss three main components of the epigenome and their role in the regulation of gene expression and present a detailed method section specific to studying each component, including data analyses, troubleshooting, and feasibility in different experimental settings. The main topics are high-throughput and targeted methods for DNA methylation analysis, nucleosome position mapping, studying epigenetic effects of gut microbiota, optical imaging for detection of epigenetic aberrations in living cells, methods for microRNA, and histone code profiling. Written for the Methods in Pharmacology and Toxicology series, the book includes the kind of detail and implementation advice to encourage success in the lab.
Authoritative and easily applicable, Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases aims to provide pharmacologists, molecular biologists, bioinformaticians, and toxicologists with a vital background on epigenetics and state-of-the-art techniques in epigenomics.
Автор: Parnham Название: Compendium of Inflammatory Diseases ISBN: 3764385308 ISBN-13(EAN): 9783764385309 Издательство: Springer Рейтинг: Цена: 139754.00 р. Наличие на складе: Поставка под заказ.
Описание: Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has revealed the underlying inflammatory pathology of many diseases and provided multiple new targets for anti-inflammatory and immunomodulatory therapy. The Encyclopedia of Inflammatory Diseases will cover the following areas: * Inflammatory Processes and Cells * Inflammatory Diseases * Mediators of Inflammation * Pharmacology of Inflammation Since inflammatory diseases and their therapy cover a broad range of scientific and medical fields, the encyclopedia will be co-edited by four international experts, a clinician and three researchers from the disciplines of immunology, biochemistry, and pharmacology, in this way providing students, basic and clinical scientists and practitioners in academia, hospitals and industry with valuable interlinked information. This living project will serve as a reliable and comprehensive data pool for everybody working in inflammation research. Owing to its dynamic nature, it will grow with time and future editions, becoming an indispensible source of information for academia, clinical practitioners and industry.
Описание: Radiology, the youngest of the major medical sciences, has undergone an extraordinary technical evolution since the discovery of X-rays. Today the fourth generation of radiologists is faced with another deci- sion: whether to become technologists subjugated to their machinery, to become sub specialists with a single skill, or to remain doctors.
Автор: Abul K. Abbas; Richard A. Flavell Название: Genetic Models of Immune and Inflammatory Diseases ISBN: 1461275202 ISBN-13(EAN): 9781461275206 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Immunomodulatory agents have been expressed in defined tissues or throughout the body, providing tools for studying the functional consequences of dysregulated expression of biologi cal response modifiers.
Автор: Nussinovitch, Udi Название: The Heart in Rheumatic, Autoimmune and Inflammatory Diseases ISBN: 0128032677 ISBN-13(EAN): 9780128032671 Издательство: Elsevier Science Рейтинг: Цена: 21054.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives.
This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe.
A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases.
Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches.
Presents an up-to-date "level of evidence" and "strengths of recommendations" for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.
Автор: Christopher H. Evans; Paul D. Robbins Название: Gene Therapy in Inflammatory Diseases ISBN: 3034895844 ISBN-13(EAN): 9783034895842 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gene therapy for inflammatory diseases is a new, burgeoning field of medicine. Edited by the undisputed pioneers of this area of research, this volume is the first devoted to its topic. It contains thirteen chapters, each written by leaders in their respective fields, that summarize the state of the art in developing novel, gene based treatments for inflammatory diseases. As well as providing an introduction to the basic concepts of gene therapy and the use of naked DNA approaches, the book describes the advances that have been made in applying them to arthritis, lupus, multiple sclerosis, diabetes, Sjogren s syndrome and transplantation.One chapter is devoted to discussing the first human clinical trials that apply gene therapy to the treatment of an inflammatory disease. As well as providing novel therapeutic approaches, gene therapy facilitates the development of new and improved animal models of disease; a chapter describing these advances is also included. As an up-to-date, timely book written by th
Автор: John R. J. Sorenson Название: Inflammatory Diseases and Copper ISBN: 0896030377 ISBN-13(EAN): 9780896030374 Издательство: Springer Рейтинг: Цена: 32651.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In 1928, it was discovered that copper was essential for normal human metabolism. A decade later, in 1938, it was observed that patients with rheu- matoid arthritis exhibited a higher than normal serum copper concentration that returned to normal with remission of this disease.
Описание: Controversy still exists regarding how early disease-modifying agents (DMA) should be commenced and whether all patients with relapsing-remitting MS should in fact be treated. With their novel, multifaceted approach to basic science, the authors of this book offer help to clinicians and hope to patients.
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