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Chemotherapy of Fungal Diseases, John F. Ryley; D. Armstrong; F.T. Boyle; M. Debono


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Автор: John F. Ryley; D. Armstrong; F.T. Boyle; M. Debono
Название:  Chemotherapy of Fungal Diseases
ISBN: 9783642754609
Издательство: Springer
Классификация:




ISBN-10: 3642754600
Обложка/Формат: Paperback
Страницы: 558
Вес: 0.81 кг.
Дата издания: 13.12.2011
Серия: Handbook of Experimental Pharmacology
Язык: English
Размер: 234 x 156 x 30
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Prous, Barcelona, 1987) and volume 544 of the Annals of the New York Academy of Sciences, entitled Antifungal Drugs, edited by Vassil St. Georgiev, and containing papers and posters presented at a most enjoyable 3-day conference held at Garden City, New York, in the autumn of 1987.


Cancer Chemotherapy in Clinical Practice

Автор: Priestman, Terrence
Название: Cancer Chemotherapy in Clinical Practice
ISBN: 0857297260 ISBN-13(EAN): 9780857297266
Издательство: Springer
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Цена: 8384.00 р.
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Описание: A simple introduction explaining the broad principles underlying chemotherapy, this book gives trainees a framework within which they can place the specific aspects of cancer chemotherapy they encounter in their everyday experience.

Chemotherapy of Parasitic Diseases

Автор: W.C. Campbell; R.S. Rew
Название: Chemotherapy of Parasitic Diseases
ISBN: 1468412353 ISBN-13(EAN): 9781468412352
Издательство: Springer
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Цена: 6986.00 р.
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Описание: "Have a chew of dulie," said Crubog . - From Bogmail, a novel by Patrick McGinley (1981) With modern techniques of chemical isolation and structure determination, the old distinction between herbal and chemical remedies has largely been broken down.

Antiviral Chemotherapy 4

Автор: John Mills; Paul A. Volberding; Lawrence Corey
Название: Antiviral Chemotherapy 4
ISBN: 1475792115 ISBN-13(EAN): 9781475792119
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Proceedings of the Fourth Triennial Symposium held in San Francisco,California, November 10-12, 1994.

Biosynthetic Products for Cancer Chemotherapy

Автор: George Pettit
Название: Biosynthetic Products for Cancer Chemotherapy
ISBN: 1468430203 ISBN-13(EAN): 9781468430202
Издательство: Springer
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Цена: 6986.00 р.
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Описание: An overall view of the cancer problem and development of cancer chemothera- 231 peutic biosynthetic products to February 1976 was presented in Volume 1.

Chemotherapy

Автор: Kurt Hellmann
Название: Chemotherapy
ISBN: 1461343542 ISBN-13(EAN): 9781461343547
Издательство: Springer
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Описание: The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease.

Concepts, Mechanisms, and New Targets for Chemotherapy

Автор: Franco M. Muggia
Название: Concepts, Mechanisms, and New Targets for Chemotherapy
ISBN: 1461358299 ISBN-13(EAN): 9781461358299
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Taxanes are restructuring treatment regimens in breast cancer, and high-dose strategies are described with peripheral blood progenitor autografting in the treatment of ovarian and breast cancers.

Molecular Aspects of Chemotherapy

Автор: David Shugar; Wojciech Rode; Edward Borowski
Название: Molecular Aspects of Chemotherapy
ISBN: 3662027429 ISBN-13(EAN): 9783662027424
Издательство: Springer
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Цена: 6986.00 р.
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Описание: While serendipity and random screening continue to fulfil a significant role in the search for new drugs, current remarkable advances in molecular biology and genetics are dictating to a profound extent the approaches employed in their development.

Special Problems in Chemotherapy

Автор: J. D. Williams; A. M. Geddes
Название: Special Problems in Chemotherapy
ISBN: 1468431226 ISBN-13(EAN): 9781468431223
Издательство: Springer
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Цена: 13974.00 р.
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Описание: The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease.

The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy

Автор: Y. Rustum
Название: The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy
ISBN: 1468456091 ISBN-13(EAN): 9781468456097
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Although 5-fluorouracil (Fura) is the drug of choice for the treat- ment of patients with advanced colorectal cancer, this agent has limited effectiveness with a reported response rate of 10-20% and a duration of response of only 6-9 months. The large percentage of treatment failures with this agent has spurred a continuing effort to delineate the mechanism(s) of resistance to Fura and to evaluate approaches that would selectively modulate the therapeutic efficacy of this agent. The therapeutic efficacy of FUra has been attributed to its selec- tive incorporation into RNA and to its inhibition of thymidylate syn- thase, leading to potent inhibition of DNA synthesis. Studies of cell lines in vitro and model systems in vivo have demonstrated that although mechanism sensitivity and resistanc; to Fura are multifactorial, in the presence of citrovorum factor (CF, 5-formyltetrahydrofolate) the site of action of Fura becomes predominantly the pronounced and pro- longed inhibition of thymidylate synthase. This action is the result of stabilization of the covalent ternary complex between FdUMP, an active metabolite of FUra, 5,10-methylenetetrahydrofolates, and thymidylate synthase. This effect of CF is thus an example of the concept of meta- bolic modulation.

Regional Chemotherapy

Автор: Maurie Markman
Название: Regional Chemotherapy
ISBN: 1468496972 ISBN-13(EAN): 9781468496970
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease.

Antiviral Chemotherapy 5

Автор: John Mills; Paul A. Volberding; Lawrence Corey
Название: Antiviral Chemotherapy 5
ISBN: 1461371503 ISBN-13(EAN): 9781461371502
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Scientists and clinicians attending the last "New Directions in Antiviral Therapy" conference in late 1994 could hardly have predicted the revolution in the management of patients with HIV infection that has occurred since.

New Drugs, Concepts and Results in Cancer Chemotherapy

Автор: Franco M. Muggia
Название: New Drugs, Concepts and Results in Cancer Chemotherapy
ISBN: 146136728X ISBN-13(EAN): 9781461367284
Издательство: Springer
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Цена: 20962.00 р.
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Описание: The decade of the 1990s will see an increasing emphasis on the modulation of chemotherapeutic drug selectivity and in the 'lock and key' approach to new targets to control malignant proliferation. The contents of this volume appropriately reflect these scientific undercurrents. An emerging powerful tool of molecular pharmacology is described by Holcenberg and Wu. Manipulation of genetic expression by modification of messenger RNA is now within our reach, and the basic concepts are suc- cinctly reviewed as a primer on future biochemical engineering of new anti- cancer molecules. Another concept that appears to be worthy of further study in both experimental and clinical chemotherapy concerns obs'ervations on the modulation of activity by the nucleoside transport inhibitor, dipyri- damole. How potentiation of several anticancer drugs occurs has practical, as well as theoretical, ramifications, discussed by Goel and HowelL Finally, O'Dwyer and La Creta present a fresh look at sensitization of chemotherapy by the hypoxic radiosensitizer, SR-2731.


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