Chemotherapy of Fungal Diseases, John F. Ryley; D. Armstrong; F.T. Boyle; M. Debono
Автор: Priestman, Terrence Название: Cancer Chemotherapy in Clinical Practice ISBN: 0857297260 ISBN-13(EAN): 9780857297266 Издательство: Springer Рейтинг: Цена: 8384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A simple introduction explaining the broad principles underlying chemotherapy, this book gives trainees a framework within which they can place the specific aspects of cancer chemotherapy they encounter in their everyday experience.
Автор: W.C. Campbell; R.S. Rew Название: Chemotherapy of Parasitic Diseases ISBN: 1468412353 ISBN-13(EAN): 9781468412352 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "Have a chew of dulie," said Crubog . - From Bogmail, a novel by Patrick McGinley (1981) With modern techniques of chemical isolation and structure determination, the old distinction between herbal and chemical remedies has largely been broken down.
Автор: John Mills; Paul A. Volberding; Lawrence Corey Название: Antiviral Chemotherapy 4 ISBN: 1475792115 ISBN-13(EAN): 9781475792119 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Fourth Triennial Symposium held in San Francisco,California, November 10-12, 1994.
Автор: George Pettit Название: Biosynthetic Products for Cancer Chemotherapy ISBN: 1468430203 ISBN-13(EAN): 9781468430202 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An overall view of the cancer problem and development of cancer chemothera- 231 peutic biosynthetic products to February 1976 was presented in Volume 1.
Автор: Kurt Hellmann Название: Chemotherapy ISBN: 1461343542 ISBN-13(EAN): 9781461343547 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease.
Автор: Franco M. Muggia Название: Concepts, Mechanisms, and New Targets for Chemotherapy ISBN: 1461358299 ISBN-13(EAN): 9781461358299 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Taxanes are restructuring treatment regimens in breast cancer, and high-dose strategies are described with peripheral blood progenitor autografting in the treatment of ovarian and breast cancers.
Автор: David Shugar; Wojciech Rode; Edward Borowski Название: Molecular Aspects of Chemotherapy ISBN: 3662027429 ISBN-13(EAN): 9783662027424 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: While serendipity and random screening continue to fulfil a significant role in the search for new drugs, current remarkable advances in molecular biology and genetics are dictating to a profound extent the approaches employed in their development.
Автор: J. D. Williams; A. M. Geddes Название: Special Problems in Chemotherapy ISBN: 1468431226 ISBN-13(EAN): 9781468431223 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease.
Описание: Although 5-fluorouracil (Fura) is the drug of choice for the treat- ment of patients with advanced colorectal cancer, this agent has limited effectiveness with a reported response rate of 10-20% and a duration of response of only 6-9 months. The large percentage of treatment failures with this agent has spurred a continuing effort to delineate the mechanism(s) of resistance to Fura and to evaluate approaches that would selectively modulate the therapeutic efficacy of this agent. The therapeutic efficacy of FUra has been attributed to its selec- tive incorporation into RNA and to its inhibition of thymidylate syn- thase, leading to potent inhibition of DNA synthesis. Studies of cell lines in vitro and model systems in vivo have demonstrated that although mechanism sensitivity and resistanc; to Fura are multifactorial, in the presence of citrovorum factor (CF, 5-formyltetrahydrofolate) the site of action of Fura becomes predominantly the pronounced and pro- longed inhibition of thymidylate synthase. This action is the result of stabilization of the covalent ternary complex between FdUMP, an active metabolite of FUra, 5,10-methylenetetrahydrofolates, and thymidylate synthase. This effect of CF is thus an example of the concept of meta- bolic modulation.
Автор: Maurie Markman Название: Regional Chemotherapy ISBN: 1468496972 ISBN-13(EAN): 9781468496970 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease.
Автор: John Mills; Paul A. Volberding; Lawrence Corey Название: Antiviral Chemotherapy 5 ISBN: 1461371503 ISBN-13(EAN): 9781461371502 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Scientists and clinicians attending the last "New Directions in Antiviral Therapy" conference in late 1994 could hardly have predicted the revolution in the management of patients with HIV infection that has occurred since.
Автор: Franco M. Muggia Название: New Drugs, Concepts and Results in Cancer Chemotherapy ISBN: 146136728X ISBN-13(EAN): 9781461367284 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The decade of the 1990s will see an increasing emphasis on the modulation of chemotherapeutic drug selectivity and in the 'lock and key' approach to new targets to control malignant proliferation. The contents of this volume appropriately reflect these scientific undercurrents. An emerging powerful tool of molecular pharmacology is described by Holcenberg and Wu. Manipulation of genetic expression by modification of messenger RNA is now within our reach, and the basic concepts are suc- cinctly reviewed as a primer on future biochemical engineering of new anti- cancer molecules. Another concept that appears to be worthy of further study in both experimental and clinical chemotherapy concerns obs'ervations on the modulation of activity by the nucleoside transport inhibitor, dipyri- damole. How potentiation of several anticancer drugs occurs has practical, as well as theoretical, ramifications, discussed by Goel and HowelL Finally, O'Dwyer and La Creta present a fresh look at sensitization of chemotherapy by the hypoxic radiosensitizer, SR-2731.
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