Advances in Mutagenesis Research, G?nter Obe; F. Cortes; P. Escalza; A. Hofmann; V.I

Автор: F. Vogel; G. R?hrborn
Название: Chemical Mutagenesis in Mammals and Man
ISBN: 3642858767 ISBN-13(EAN): 9783642858765
Издательство: Springer
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Описание: Encouraged by the results with radiation genetics, the editors of this volume have tried since 1963 to organize a team of scientists in Heidelberg who would examine the problem of chemical mutagenesis in mammals with a variety of methods. Meanwhile, other organizations have also become interested in this problem and various teams, particularly in the U.S.A., but also in West Germany, are working in this field. This development is very auspicious; the spectrum of our methods does permit limited conclusions as to the mutagenic effects of chemical substances in mammals, but we are still far away from a thorough determination of all the genetically relevant effects. New methods must be developed. This volume is the result of a request by the Chairman of the "Gesellschaft fUr Anthropologie und Humangenetik", Frau Professor Dr. I. SCHWIDETZKY (Mainz), that one of us (F.V.) organize a symposium concerning mutation research in the framework of its annual meeting on October 7, 1969. The most sensible approach seemed to be one of centering the discussion on the test methods employed in mutagenicity research with mammals. With the aid of the Deutsche Forschungsgemeinschaft and the pharma- ceutical industry it was possible to invite scientists from the U.S.A. We wish to thank Firma Thomae, Biberach, Firma Bayer, Leverkusen, and Firma Boehringer, Mannheim, for their contributions. We wish to thank Dr. HAsso SCHROEDER especially for his efforts on our behalf.

Автор: G?nter Obe; E.E. Castilla; R. Drouin; J. Filipski;
Название: Advances in Mutagenesis Research 2
ISBN: 3642756018 ISBN-13(EAN): 9783642756016
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Описание: The new field of applied genetic research, genetic toxicology and mutation research investigates the muta- genicity and cancerogenicity of chemicals and other agents.

Автор: M. Bauchinger; G?nter Obe; F.K. Ennever; H. Hayats
Название: Advances in Mutagenesis Research
ISBN: 3642749577 ISBN-13(EAN): 9783642749575
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Описание: The new field of applied genetic research, genetic toxicology and mutation research investigates the mutagenicity and cancerogenicity of chemicals and other agents.

Автор: G?nter Obe; H.H. Evans; D. Frankenberg; M. Franken
Название: Advances in Mutagenesis Research
ISBN: 3642762344 ISBN-13(EAN): 9783642762345
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Описание: Applied genetic research, genetic toxicology and mutation research investigate the mutagenicity and cancerogenicity of chemicals and other agents.

Автор: Y.F. Bogdanov; E. Dikomey; N.A. Liapunova; W.-U. M
Название: Advances in Mutagenesis Research
ISBN: 3642781950 ISBN-13(EAN): 9783642781957
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Описание: Applied genetic research, genetic toxicology and mutation research investigate the mutagenicity of chemicals and other agents. Permanent mutation in genes and chromosomes can be induced by a plethora of agents, including ionizing and nonionizing radiations, chemicals, and viruses.

Автор: Mittelman David
Название: Stress-Induced Mutagenesis
ISBN: 1461462797 ISBN-13(EAN): 9781461462798
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Описание: This book covers pathways of stress-induced mutagenesis, which may yield models for genome instability underlying some cancers and genetic diseases, resistance to chemotherapeutic and antibiotic drugs, pathogenicity of microbes, and other important processes.

Автор: Shondra M. Pruett-Miller
Название: Chromosomal Mutagenesis
ISBN: 1493955411 ISBN-13(EAN): 9781493955411
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols.

Автор: Christopher W. Lawrence
Название: Induced Mutagenesis
ISBN: 1468443844 ISBN-13(EAN): 9781468443844
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Описание: The second was to examine the implications of such principles for the execution and evaluation of test procedures, and critically assess the research areas that need further attention in order to improve the interpretation of test results.

Автор: Frederick De Serres
Название: Comparative Chemical Mutagenesis
ISBN: 146133411X ISBN-13(EAN): 9781461334118
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Описание: ) 27709 The Workshop on Comparative Chemical Mutagenesis was orga- nized to begin the process of problem identification and resolution concerning our needs to evaluate the data on test chemicals arising from assays for mutagenic activity on laboratory organisms.

Автор: A. Kappas
Название: Mechanisms of Environmental Mutagenesis-Carcinogenesis
ISBN: 1461366984 ISBN-13(EAN): 9781461366980
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Описание: Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy.

Автор: W. Generoso
Название: DNA Repair and Mutagenesis in Eukaryotes
ISBN: 1468438441 ISBN-13(EAN): 9781468438444
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Описание: Not many years ago most discussion of mutation induction by physical and chemical agents concentrated on the initial lesions induced in the DNA with the implicit assumption that once the lesions were made they were converted almost automatically to mutations by relatively simple processes associated with DNA replication.

Автор: Greg Davis; Kevin J. Kayser
Название: Chromosomal Mutagenesis
ISBN: 161737833X ISBN-13(EAN): 9781617378331
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Описание: In Chromosomal Mutagenesis, a team of experts provide a variety of chromosomal manipulation techniques, including insertional gene disruptions, gene knockouts, stimulated homologous recombination techniques and other novel tools, for both prokaryotic and eukaryotic organisms, and attempt to expand the genetic toolbox beyond model organisms.