Recent Advances in Cell Biology of Acute Leukemia, Wolf-Dieter Ludwig; Eckhard Thiel

Автор: Vaskar Saha; Pamela Kearns
Название: New Agents for the Treatment of Acute Lymphoblastic Leukemia
ISBN: 1489985719 ISBN-13(EAN): 9781489985712
Издательство: Springer
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Цена: 26120.00 р.
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Описание: It is increasingly recognized that the natural history of cancer formation is a complex path taking many years to develop to a clinically apparent stage in most cases. However, with advancing knowledge comes a whole plethora of questions explored in this book.

Автор: Abla
Название: Acute Promyelocytic Leukemia
ISBN: 3319642561 ISBN-13(EAN): 9783319642567
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on secondary APL and therapy, late effects, rare presentations such as APL in the elderly and during pregnancy, and rare APL variants that may represent therapeutic challenges.Written by top experts in the field, Acute Promyelocytic Leukemia: A Clinical Guide is a valuable resource for clinicians and researchers who treat and investigate this disease in children and adults.

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493939890 ISBN-13(EAN): 9781493939893
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana
Название: Biology and Therapy of Acute Leukemia
ISBN: 1461296331 ISBN-13(EAN): 9781461296331
Издательство: Springer
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Цена: 27951.00 р.
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Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984

Автор: Sami Malek
Название: Advances in Chronic Lymphocytic Leukemia
ISBN: 1493953893 ISBN-13(EAN): 9781493953899
Издательство: Springer
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Цена: 20896.00 р.
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Описание: In this book, the authors focus on crucial aspects of chronic lymphocytic leukemia (CLL) pathogenesis and delineate the known and unknown in CLL to inform readers and to motivate out of the box thinking in future CLL research.

Автор: Paolo Fortina; Eric Londin; Jason Y. Park; Larry J
Название: Acute Myeloid Leukemia
ISBN: 1493971409 ISBN-13(EAN): 9781493971404
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival.

Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana
Название: Biology and Therapy of Acute Leukemia
ISBN: 0898387280 ISBN-13(EAN): 9780898387285
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984

Автор: Sami Malek
Название: Advances in Chronic Lymphocytic Leukemia
ISBN: 1461480507 ISBN-13(EAN): 9781461480501
Издательство: Springer
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Цена: 23508.00 р.
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Описание: In this book, the authors focus on crucial aspects of chronic lymphocytic leukemia (CLL) pathogenesis and delineate the known and unknown in CLL to inform readers and to motivate out of the box thinking in future CLL research.

Автор: Emil J. Freireich; Hagop Kantarjian
Название: Leukemia: Advances in Research and Treatment
ISBN: 0792319672 ISBN-13(EAN): 9780792319672
Издательство: Springer
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Цена: 51570.00 р.
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Автор: Emil J. Freireich; Hagop Kantarjian
Название: Leukemia: Advances in Research and Treatment
ISBN: 1461363489 ISBN-13(EAN): 9781461363484
Издательство: Springer
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Цена: 13974.00 р.
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Описание: As a result, this multi-authored volume, devoted to advances which have occurred over the last seven years, provides the reader with an important new understanding of leukemia, but perhaps even more important, predicts analogous, new developments in the other malignant diagnoses.

Автор: Anjali S. Advani; Hillard M. Lazarus
Название: Adult Acute Lymphocytic Leukemia
ISBN: 149395766X ISBN-13(EAN): 9781493957668
Издательство: Springer
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Цена: 30745.00 р.
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Описание: The current explosion of new areas of controversy in the treatment of acute lymphocytic leukemia in adults and young adults makes this comprehensive book a much needed reference for hematologists and oncologists. This book assembles leading authorities from around the globe to cover the full spectrum of ALL subtypes and their treatments. Specific topics of discussion include indications for allogeneic bone marrow transplant in first complete remission, the role of minimal residual disease in making treatment decisions, the treatment of young adults, and the treatment of Philadelphia chromosome positive ALL with the advent of the tyrosine kinase inhibitors. This is the first book to focus exclusively on the adult ALL patient. It provides a complete overview of diagnosis, molecular pathogenesis, evaluation, and treatment for this important patient population.