Автор: Anjali S. Advani; Hillard M. Lazarus Название: Adult Acute Lymphocytic Leukemia ISBN: 149395766X ISBN-13(EAN): 9781493957668 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The current explosion of new areas of controversy in the treatment of acute lymphocytic leukemia in adults and young adults makes this comprehensive book a much needed reference for hematologists and oncologists. This book assembles leading authorities from around the globe to cover the full spectrum of ALL subtypes and their treatments. Specific topics of discussion include indications for allogeneic bone marrow transplant in first complete remission, the role of minimal residual disease in making treatment decisions, the treatment of young adults, and the treatment of Philadelphia chromosome positive ALL with the advent of the tyrosine kinase inhibitors. This is the first book to focus exclusively on the adult ALL patient. It provides a complete overview of diagnosis, molecular pathogenesis, evaluation, and treatment for this important patient population.
Автор: Michael Andreeff Название: Targeted Therapy of Acute Myeloid Leukemia ISBN: 1493939890 ISBN-13(EAN): 9781493939893 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.
Автор: Judith E. Karp Название: Acute Myelogenous Leukemia ISBN: 1617376752 ISBN-13(EAN): 9781617376757 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is a timely compilation of new concepts in the molecular pathogenesis and molecular therapy of acute myelogenous leukemia (AML). The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities.
Автор: Hiddemann Название: Handbook of Acute Leukemia ISBN: 3319267701 ISBN-13(EAN): 9783319267708 Издательство: Springer Рейтинг: Цена: 8384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an overview of the key developments in both acute lymphocytic leukemia and acute myeloid leukemia with a comprehensive guide to the epidemiology, pathogenesis, etiology, clinical manifestations, classification, diagnosis, and staging as well as the most recent developments in the therapeutic landscape for acute leukemia.
Автор: Paolo Fortina; Eric Londin; Jason Y. Park; Larry J Название: Acute Myeloid Leukemia ISBN: 1493971409 ISBN-13(EAN): 9781493971404 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival.
Автор: Vaskar Saha; Pamela Kearns Название: New Agents for the Treatment of Acute Lymphoblastic Leukemia ISBN: 1489985719 ISBN-13(EAN): 9781489985712 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It is increasingly recognized that the natural history of cancer formation is a complex path taking many years to develop to a clinically apparent stage in most cases. However, with advancing knowledge comes a whole plethora of questions explored in this book.
Автор: Michael Andreeff Название: Targeted Therapy of Acute Myeloid Leukemia ISBN: 1493913921 ISBN-13(EAN): 9781493913923 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.
Автор: A. Hagenbeek; B. L?wenberg Название: Minimal Residual Disease in Acute Leukemia 1986 ISBN: 9401083983 ISBN-13(EAN): 9789401083980 Издательство: Springer Рейтинг: Цена: 38433.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Relapse of leukemia following successful remission-induction therapy remains a major obstacle in the treatment of patients with acute leukemia.
Автор: B. L?wenberg; A. Hagenbeek Название: Minimal Residual Disease in Acute Leukemia ISBN: 9401090025 ISBN-13(EAN): 9789401090025 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: They include the production and ap plication of monoclonal antibodies against differentiation antigens on the cell sur face, the use of pulse cytophotometry - and cell sorter techniques, the employment of cytogenetics, the development of culture techniques for selective growth of precursor cells and several others.
Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana Название: Biology and Therapy of Acute Leukemia ISBN: 1461296331 ISBN-13(EAN): 9781461296331 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984
Автор: Wolf-Dieter Ludwig; Eckhard Thiel Название: Recent Advances in Cell Biology of Acute Leukemia ISBN: 3642848974 ISBN-13(EAN): 9783642848971 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The development of new techniques such as immuno- phenotyping, cytogenetic investigations and, more recently, molecular studies has considerably increased our diagnostic repertoire and broadened our ideas about the biology of acute leukemias.
Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana Название: Biology and Therapy of Acute Leukemia ISBN: 0898387280 ISBN-13(EAN): 9780898387285 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984
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