Автор: Markus Joerger; Michael Gnant Название: Prevention of Bone Metastases ISBN: 3642446140 ISBN-13(EAN): 9783642446146 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention.
Автор: Vassiliou Название: Bone Metastases ISBN: 9400775687 ISBN-13(EAN): 9789400775688 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Vassilios Vassiliou; Edward Chow; Dimitrios Kardam Название: Bone Metastases ISBN: 9402405003 ISBN-13(EAN): 9789402405002 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface. I FUNDAMENTAL CONCEPTS.1 Pathophysiology of metastatic bone disease. 2 Bone metastases: epidemiology, clinical picture, SREs and prognosis. 3 Pain in bone metastases: types and mechanisms. II INVESTIGATIONS OF BONE METASTASES. 4 Radiological evaluations: radiography, CT, MRI. 5 Nuclear medicine imaging modalities: bone scintigraphy, PET-CT, SPECT. 6. Bone turnover markers. 7. New omics approaches for bone metastases. III THERAPEUTIC MANAGEMENT. 8 Analgesic treatment for bone mets. 9. Radiotherapy: external beam and radio-surgery. 10 Radionuclide therapy.11. Bisphosphonates. 12 New targeted therapies for bone metastases. 13. Chemotherapy and hormone therapy. 14 HIFU/Radioablation. 15 Neuropathic bone metastases. 16. Spinal cord compression and cauda equina compression. 17 Pathological and impending fracture. 18 Re-irradiation. 19. Bone metastases in elderly patients. 20. Management of metastatic bone disease in the elderly with bisphosphonates and RANKL inhibitors: effectiveness and safety. IV ASSESMENT OF THERAPEUTIC RESPONSE. 21 Radiological and nuclear medicine imaging modalities. 22 Clinical assessment measures. 23 Outcome measures in bone metastases clinical trials. 24 Quality of life in patients suffering from metastatic skeletal disease. V COST OF MANAGING METASTATIC BONE DISEASE. 25 Cost effectiveness of treatment modalities for bone metastases. Index.
Описание: The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients.
Автор: Jeffrey J. Raizer; Lauren E. Abrey Название: Brain Metastases ISBN: 1489996249 ISBN-13(EAN): 9781489996244 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Brain metastases are the most dreaded complication of systemic cancer, affecting approximately 170,000 people a year, a far greater incidence than primary brain tumors. Advances in modern chemotherapy have led to an improved control of system cancers, often with agents that poorly penetrate the central nervous system, resulting in an increasing incidence of brain metastases. Traditional chemotherapy has had little impact on brain metastases. The main therapeutic option is radiation therapy, and in a small number of patients - surgery. However, refinements in all of these treatments offer some positive outcomes and an increased ability to stratify patients based on certain criteria.
This book will bring current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neuro-surgeons, radiation oncologists, medical oncologists, and neuro-oncologists, as well as an overview for physicians in training.
Автор: Pointillart Название: Vertebral Metastases ISBN: 2287597522 ISBN-13(EAN): 9782287597527 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, the result of close collaboration between two very specialized centers, one in spinal surgery, the other in oncology, was written to take stock of the current data on vertebral metastases. It is intended as both a pratical guide for all those involved in this field of care and a didactic reference for those who are less familiar with either of these specialties. All aspects of current knowledge of metastases are considered. Regarding diagnostics, MRI is at present indispensable and nessecitates a broad iconography. In the therapeutics section, so as to restituate vertebral metastasis in its proper general context, a chapter is devoted to the particularities of the treatment in terms of the primary cancer. This is fundamental since the sensitivity of tumors to systemic treatment is clearly not the same from one case to another. The role of surgery in vertebral metastases has changed completely over the last ten years with the increasing use osteosynthesis combined with decompressive procedures. The explanation of these techniques and their indications is largely based upon providing a suitable response to the mechanical problems posed at each location in the spinal column. Vertebroplasty and biphosphonates, two recent additions to the therapeutic armamentarium are detailed, along with conventional treatments such as radiation therapy and the comprehensive approach to pain management. In the present context of technological advances against vertebral metastases, physicians must not lose sight of the patient as an individual. This imperative prompted us to include a chapter on nursing and psychological cared. Another chapter addresses the continuity of care, placing responsability for the patient's management at present solely in the hands of a multidisciplinary team. A methodological review of the literature concludes that there still remains much work to be done for better assessment of the responsability for the welfare of these patients. Two leading US spinal surgeons have accepted to endorse this manuscript: J.P. Farcy and N. Sundaresan. The question of their contributing to the book was naturally raised. However, it seemed preferable to preserve the homogenous spirit driving the original group of collaborators.
Автор: Dominique G. Poitout Название: Bone Metastases ISBN: 144713253X ISBN-13(EAN): 9781447132530 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The steady progress in diagnosis and treatment of bone cancer in the last decade has dramatically changed the prognosis of cancer patients, improving significantly the overall survival rate and quality of life.
Автор: Hayat, M. A. Название: Brain Metastases from Primary Tumors, Volume 3 ISBN: 0128035080 ISBN-13(EAN): 9780128035085 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "
Brain Metastases from Primary Tumors Volume Three: Epidemiology, Biology, and Therapy of Melanoma and Other Cancers" provides a comprehensive overview of the metastasis of cancer, the main cause of approximately 90% of cancer associated deaths, yet the mechanisms governing this clinically important process remain poorly understood.
Melanoma is the third most common diagnosis among patients with brain metastases, after lung and breast cancer. Approximately 75% of patients with metastatic melanoma develop brain metastases during the course of their disease. Although tumorigenesis of melanoma remains poorly understood, recent advances in gene expression profiling have revealed molecular mechanisms of this deadly disease. In addition, high-throughput gene expression has many advantages over techniques in cancer transcriptomic studies and has led to the discovery of numerous diagnostic, prognostic, and therapeutic targets, which are also detailed in this book.
The book discusses the link between primary tumors and brain metastasis of melanoma, including molecular mechanisms, treatment options, prognosis, and general applications. Comprehensive chapters discuss systemic therapy, integrin inhibitors, stereotaxic radiosurgery, and more, making this book a great resource for neurooncologists, neurosurgeons, neurologists, and cancer researchers. Presents the only comprehensive reference detailing the link between primary cancers and brain metastases in melanomaAids the target audience in discussing various treatment options for patients with brain metastases from melanomaEdited work with chapters authored by leaders in the field around the globe the broadest, most expert coverage available"
Автор: Vauthey Название: Liver Metastases ISBN: 1849966842 ISBN-13(EAN): 9781849966849 Издательство: Springer Рейтинг: Цена: 26552.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: After giving a biological overview of liver metastases and current methods of detection and diagnosis, this book explores in detail each of the possible major treatment modalities. It closes with a look at germane health economics issues.
Автор: Lauren E. Abrey; Marc Chamberlain; Herbert Engelha Название: Leptomeningeal Metastases ISBN: 1461498902 ISBN-13(EAN): 9781461498902 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leptomeningeal Metastases is intended to provide the reader with an overview of the state-of-the-art therapy for the cancer patient with leptomeningeal cancer with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies.
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