Автор: Jochen A. Werner; R. Kim Davis Название: Metastases in Head and Neck Cancer ISBN: 3642622631 ISBN-13(EAN): 9783642622632 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: -Richly illustrated; 109 illustrations, 57 in color
-Cover a wide range of diagnostic and theraputic techniques, i.e. MRI, PET, surgical treatment, radiation therapy
Автор: Hayat, M. A. Название: Brain Metastases from Primary Tumors, Volume 3 ISBN: 0128035080 ISBN-13(EAN): 9780128035085 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "
Brain Metastases from Primary Tumors Volume Three: Epidemiology, Biology, and Therapy of Melanoma and Other Cancers" provides a comprehensive overview of the metastasis of cancer, the main cause of approximately 90% of cancer associated deaths, yet the mechanisms governing this clinically important process remain poorly understood.
Melanoma is the third most common diagnosis among patients with brain metastases, after lung and breast cancer. Approximately 75% of patients with metastatic melanoma develop brain metastases during the course of their disease. Although tumorigenesis of melanoma remains poorly understood, recent advances in gene expression profiling have revealed molecular mechanisms of this deadly disease. In addition, high-throughput gene expression has many advantages over techniques in cancer transcriptomic studies and has led to the discovery of numerous diagnostic, prognostic, and therapeutic targets, which are also detailed in this book.
The book discusses the link between primary tumors and brain metastasis of melanoma, including molecular mechanisms, treatment options, prognosis, and general applications. Comprehensive chapters discuss systemic therapy, integrin inhibitors, stereotaxic radiosurgery, and more, making this book a great resource for neurooncologists, neurosurgeons, neurologists, and cancer researchers. Presents the only comprehensive reference detailing the link between primary cancers and brain metastases in melanomaAids the target audience in discussing various treatment options for patients with brain metastases from melanomaEdited work with chapters authored by leaders in the field around the globe the broadest, most expert coverage available"
Автор: Vauthey Название: Liver Metastases ISBN: 1849966842 ISBN-13(EAN): 9781849966849 Издательство: Springer Рейтинг: Цена: 26552.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: After giving a biological overview of liver metastases and current methods of detection and diagnosis, this book explores in detail each of the possible major treatment modalities. It closes with a look at germane health economics issues.
Автор: Lauren E. Abrey; Marc Chamberlain; Herbert Engelha Название: Leptomeningeal Metastases ISBN: 1461498902 ISBN-13(EAN): 9781461498902 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leptomeningeal Metastases is intended to provide the reader with an overview of the state-of-the-art therapy for the cancer patient with leptomeningeal cancer with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies.
Автор: Markus Joerger; Michael Gnant Название: Prevention of Bone Metastases ISBN: 3642446140 ISBN-13(EAN): 9783642446146 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention.
Описание: The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients.
Автор: Pointillart Название: Metastases vertebrales ISBN: 2287337431 ISBN-13(EAN): 9782287337437 Издательство: Springer Рейтинг: Цена: 15896.00 р. Наличие на складе: Поставка под заказ.
Описание: Nous avons souhait une nouvelle dition sans refonte compl te de cet ouvrage, car le succ?'s de la premi re dition montre que le principe de ce livre est bien adapt une prise en charge multidisciplinaire de cette pathologie complexe. L actualisation des progr?'s r alis?'s sur le plan technique par chacun des acteurs tant sur le plan diagnostique que th rapeutique tait n cessaire et confirme la qualit de r sultat d une entreprise commune au service d un patient dans une situation particuli rement d licate. Il se veut pratique pour chacun des acteurs de la prise en charge et didactique pour ceux qui sont moins sp cialis?'s dans tel ou tel domaine. Cela nous a amen faire des choix, bien s r discutables, entra nant des explications parfois une peu trop videntes pour les connaisseurs, un peu trop techniques pour les n ophytes, des r p titions pour que chacun trouve dans son chapitre ce qui l int resse. Deux sujets m ritent une attention particuli re: la place de l IRM dans la strat gie diagnostique et th rapeutique et la place de la chirurgie vert brale dans la strat gie globale de la prise en charge de patients atteints de m tastase vert brale. La constatation unanime est que l IRM est l examen radiologique de r f rence du diagnostic et du bilan de la m tastase vert brale qui, au-del, permet un diagnostic pr coce notamment du retentissement neurologique pr clinique augurant d un meilleur pronostic fonctionnel. N anmoins, la place de l IRM doit tre situ e dans le contexte de la maladie canc reuse trait e et du retentissement sur la d cision th rapeutique globale et g n rale, ainsi que sur l avenir des patients. Le PET-Scan va trouver progressivement sa place de mani re plus pr cise. L IRM ne peut et ne doit pas tre pratiqu e de fa on syst matique en dehors d l ments de suspicion clinique, mais si elle est indiqu e, rien ne doit la retarder, car un diagnostic pr coce permet des traitements plus efficaces et moins invasifs. Les progr?'s et la diffusion de la vert broplastie sur les dix derni res ann es ont encore modifi?'s la prise en charge des patients: elle peut remplacer la chirurgie vert brale. Si elle est int gr e tr?'s t t dans la d cision th rapeutique et portant ventuellement sur plusieurs segments osseux, associ e la chirurgie, elle permet de r duire la longueur des montages et all ger d autant les suites th rapeutiques. C est une fois de plus l association des th rapeutiques, chacun apportant au patient sa modeste participation, n anmoins fondamentale, qui am liore le pronostic fonctionnel de nombreux patients.
Автор: Vassiliou Название: Bone Metastases ISBN: 9400775687 ISBN-13(EAN): 9789400775688 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Vassilios Vassiliou; Edward Chow; Dimitrios Kardam Название: Bone Metastases ISBN: 9402405003 ISBN-13(EAN): 9789402405002 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface. I FUNDAMENTAL CONCEPTS.1 Pathophysiology of metastatic bone disease. 2 Bone metastases: epidemiology, clinical picture, SREs and prognosis. 3 Pain in bone metastases: types and mechanisms. II INVESTIGATIONS OF BONE METASTASES. 4 Radiological evaluations: radiography, CT, MRI. 5 Nuclear medicine imaging modalities: bone scintigraphy, PET-CT, SPECT. 6. Bone turnover markers. 7. New omics approaches for bone metastases. III THERAPEUTIC MANAGEMENT. 8 Analgesic treatment for bone mets. 9. Radiotherapy: external beam and radio-surgery. 10 Radionuclide therapy.11. Bisphosphonates. 12 New targeted therapies for bone metastases. 13. Chemotherapy and hormone therapy. 14 HIFU/Radioablation. 15 Neuropathic bone metastases. 16. Spinal cord compression and cauda equina compression. 17 Pathological and impending fracture. 18 Re-irradiation. 19. Bone metastases in elderly patients. 20. Management of metastatic bone disease in the elderly with bisphosphonates and RANKL inhibitors: effectiveness and safety. IV ASSESMENT OF THERAPEUTIC RESPONSE. 21 Radiological and nuclear medicine imaging modalities. 22 Clinical assessment measures. 23 Outcome measures in bone metastases clinical trials. 24 Quality of life in patients suffering from metastatic skeletal disease. V COST OF MANAGING METASTATIC BONE DISEASE. 25 Cost effectiveness of treatment modalities for bone metastases. Index.
Автор: Jeffrey J. Raizer; Lauren E. Abrey Название: Brain Metastases ISBN: 1489996249 ISBN-13(EAN): 9781489996244 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Brain metastases are the most dreaded complication of systemic cancer, affecting approximately 170,000 people a year, a far greater incidence than primary brain tumors. Advances in modern chemotherapy have led to an improved control of system cancers, often with agents that poorly penetrate the central nervous system, resulting in an increasing incidence of brain metastases. Traditional chemotherapy has had little impact on brain metastases. The main therapeutic option is radiation therapy, and in a small number of patients - surgery. However, refinements in all of these treatments offer some positive outcomes and an increased ability to stratify patients based on certain criteria.
This book will bring current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neuro-surgeons, radiation oncologists, medical oncologists, and neuro-oncologists, as well as an overview for physicians in training.
Автор: Robert D. Rubens; Ignac Fogelman Название: Bone Metastases ISBN: 1447132564 ISBN-13(EAN): 9781447132561 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: They cover the biology and pathophysiology, hypercalcaemia, imaging, assessment of response to treatment, types of treatment (systemic, radiotherapy, surgery), and symptomatic and supportive care.
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