Enzymology and Molecular Biology of Carbonyl Metabolism 3, David W. Crabb; Henry Weiner; Bendicht Wermuth

Автор: Henry Weiner; David W. Crabb; T. Geoffrey Flynn
Название: Enzymology and Molecular Biology of Carbonyl Metabolism 4
ISBN: 1461362598 ISBN-13(EAN): 9781461362593
Издательство: Springer
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Описание: The Sixth International Workshop on the Enzymology and Molecular Biology of Carbonyl Metabolism was held outside of Dublin, Ireland at the end of June, 1992. During the past decade site directed mutagenesis to probe for the active site of an enzyme has become part of traditional enzymology;

Автор: Henry Weiner; Ronald Lindahl; David W. Crabb; T. G
Название: Enzymology and Molecular Biology of Carbonyl Metabolism 6
ISBN: 1461376920 ISBN-13(EAN): 9781461376927
Издательство: Springer
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Описание: Proceedings of the 8th International Workshop held in Deadwood, South Dakota, June 29-July 3, 1996

Автор: Henry Weiner; Edmund Maser; David W. Crabb; Ronald
Название: Enzymology and Molecular Biology of Carbonyl Metabolism 7
ISBN: 1461371465 ISBN-13(EAN): 9781461371465
Издательство: Springer
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Описание: Prior to the start of the eighth meeting, I had the good sense to ask Professor Rosa Angela Canuto of Turin, Italy if she would help me organize the ninth meeting. Though the social and cultural aspects of the meeting were outstanding, the pur- pose of the meeting was to exchange scientific information about the status of the three enzyme systems.

Автор: Henry Weiner; Roger S. Holmes; Bendicht Wermuth
Название: Enzymology and Molecular Biology of Carbonyl Metabolism 5
ISBN: 1461358086 ISBN-13(EAN): 9781461358084
Издательство: Springer
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Описание: Since the inception of these meetings in 1982, they have always been a satellite of the International Society for Biomedical Research on Alcoholism meeting. At our 1992 meeting in Dublin we learned that the next ISBRA meeting would be held in Brisbane, of all our previous meetings, I was very concerned Australia.

Автор: Spies, Maria
Название: Methods in Enzymology
ISBN: 012809267X ISBN-13(EAN): 9780128092675
Издательство: Elsevier Science
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Описание: Single-Molecule Enzymology, Part A, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in single-molecule enzymology, and includes sections on such topics as force-based and hybrid approaches, fluorescence, high-throughput sm enzymology, nanopores, and tethered particle motion.

Автор: P. Jeanteur
Название: Molecular and Cellular Enzymology
ISBN: 3642785832 ISBN-13(EAN): 9783642785832
Издательство: Springer
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Описание: Aspects such as the protein-ligand relationship, recognition, protein evolution by point mutation, enzyme-substrate interactions, behaviour of an enzyme in a living cell, control and dynamics of enzyme networks as well as the physico-chemical background of enzyme actions and multi-enzyme complexes are comprehensively treated in this volume.

Автор: Gregory I. Mashanov; Christopher Batters
Название: Single Molecule Enzymology
ISBN: 149396190X ISBN-13(EAN): 9781493961900
Издательство: Springer
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Описание: This an ideal guide for the diverse community of molecular biologists, biochemists, and biophysicists studying enzymes in detail. Experts in the field provide procedures which enable the extraction of detailed information about enzyme work cycles.

Автор: Greg Lever
Название: Large-Scale Quantum-Mechanical Enzymology
ISBN: 3319193503 ISBN-13(EAN): 9783319193502
Издательство: Springer
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Описание: This work establishes linear-scaling density-functional theory (DFT) as a powerful tool for understanding enzyme catalysis, one that can complement quantum mechanics/molecular mechanics (QM/MM) and molecular dynamics simulations. The thesis reviews benchmark studies demonstrating techniques capable of simulating entire enzymes at the ab initio quantum-mechanical level of accuracy. DFT has transformed the physical sciences by allowing researchers to perform parameter-free quantum-mechanical calculations to predict a broad range of physical and chemical properties of materials. In principle, similar methods could be applied to biological problems. However, even the simplest biological systems contain many thousands of atoms and are characterized by extremely complex configuration spaces associated with a vast number of degrees of freedom. The development of linear-scaling density-functional codes makes biological molecules accessible to quantum-mechanical calculation, but has yet to resolve the complexity of the phase space. Furthermore, these calculations on systems containing up to 2,000 atoms can capture contributions to the energy that are not accounted for in QM/MM methods (for which the Nobel prize in Chemistry was awarded in 2013) and the results presented here reveal profound shortcomings in said methods.

Автор: Price & Stevens
Название: Fundamentals of Enzymology. 3ed.IE
ISBN: 019850229X ISBN-13(EAN): 9780198502296
Издательство: Oxford Academ
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Описание: Enzymes are biological catalysts that have a number of remarkable properties. Fundamentals of Enzymology, 3rd ed builds on the strengths of the previous two editions to show how we can understand these properties and explain how enzymes work in cells and organisms and how they can be clinically and commercially exploited.