Описание: Discusses and reports on integrated QSAR models, combined into a unique hybrid system. This book assesses the needs of regulators for pesticide approval and how these needs affect QSAR models. It combines theoretical discussion with practical examples, and includes five worked examples of hybrid systems.
Автор: Cox Jr. Название: Quantitative Health Risk Analysis Methods ISBN: 1441938508 ISBN-13(EAN): 9781441938503 Издательство: Springer Рейтинг: Цена: 24456.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book grew out of an effort to salvage a potentially useful idea for greatly simplifying traditional quantitative risk assessments of the human health consequences of using antibiotics in food animals. In 2001, the United States FDA's Center for Veterinary Medicine (CVM) (FDA-CVM, 2001) published a risk assessment model for potential adverse human health consequences of using a certain class of antibiotics, fluoroquinolones, to treat flocks of chickens with fatal respiratory disease caused by infectious bacteria. CVM's concern was that fluoroquinolones are also used in human medicine, raising the possibility that fluoroquinolone-resistant strains of bacteria selected by use of fluoroquinolones in chickens might infect humans and then prove resistant to treatment with human medicines in the same class of antibiotics, such as ciprofloxacin. As a foundation for its risk assessment model, CVM proposed a dramatically simple approach that skipped many of the steps in traditional risk assessment. The basic idea was to assume that human health risks were directly proportional to some suitably defined exposure metric. In symbols: Risk = K Exposure, where "Exposure" would be defined in terms of a metric such as total production of chicken contaminated with fluoroquinolone-resistant bacteria that might cause human illnesses, and "Risk" would describe the expected number of cases per year of human illness due to fluoroquinolone-resistant bacterial infections caused by chicken and treated with fluoroquinolones.
Автор: Roland R. Watson Название: Drug and Alcohol Abuse Prevention ISBN: 1461267730 ISBN-13(EAN): 9781461267737 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume of our new series, Drug and Alcohol to reduce the use and Abuse Reviews, focuses on stategies abuse of common compounds known to cause major damage to health: alcohol, tobacco, and illicit drugs such as cocaine and heroin.
Автор: Denise De Micheli; Andr? Luiz Monezi Andrade; Eroy Название: Drug Abuse in Adolescence ISBN: 3319367439 ISBN-13(EAN): 9783319367439 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Focusing on two central themes--the psychobiological evolution from youth to adult and the effects of drugs on the developing central nervous system--this important reference elucidates the mechanisms of chemical dependency in adolescents. Its multidisciplinary coverage analyzes addiction across major domains of human functioning against the backdrop of hormonal, cognitive, and other changes that accompany the transition to adulthood. Chapters discuss legal as well as illicit drugs, examine age-related social contexts, and present the latest findings on links between drug use and mental disorders.
Throughout, the contributors make clear that education is more valuable to understanding--and preventing--substance abuse than are prohibition and zero-tolerance thinking.
Included among the topics:
Cognitive development, learning, and drug use.
Neurobiology of the action of drugs of abuse.
Findings in adolescents with substance dependence based on neuroimaging tests.
Alcohol abuse in adolescents: relevance of animal models.
Effects of chronic drug abuse on the chronobiology of sleep in adolescents.
Neurological and cognitive disorders arising from the chronic use of drugs of abuse.
The multiple lenses for understanding its subject and the sensitivity with which causal nuances are treated make Neuroscience of Drug Abuse in Adolescence an invaluable resource for clinical and child psychologists, psychiatrists, social workers, and addiction counselors.
This book focuses on the food safety challenges in the vegetable industry from primary production to consumption. It describes existing and innovative quantitative methods that could be applied to the vegetable industry for food safety and quality, and suggests ways in which such methods can be applied for risk assessment. Examples of application of food safety objectives and other risk metrics for microbial risk management in the vegetable industry are presented. The work also introduces readers to new preservation and packaging methods, advanced oxidative processes (AOPs) for disinfection, product shelf-life determination methods, and rapid analytic methods for quality assessment based on chemometrics applications, thus providing a quantitative basis for the most important aspects concerning safety and quality in the vegetable sector.
Автор: W.K. Bickel; R.J. DeGrandpre Название: Drug Policy and Human Nature ISBN: 1489935932 ISBN-13(EAN): 9781489935939 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Roland R. Watson Название: Drug Abuse Treatment ISBN: 1461267242 ISBN-13(EAN): 9781461267249 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This fourth volume of Drug and Alcohol Abuse Reviews focuses on the strategies currently thought best for the treatment of drugs of abuse. Although the main emphasis is on the treatment of illicit drug use, a major cofactor in damaging the health of drug users is nicotine (tobacco) addiction, whose treatment is also reviewed.
Автор: G. Serban Название: Social and Medical Aspects of Drug Abuse ISBN: 9401163227 ISBN-13(EAN): 9789401163224 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Despite the fact that the use of most drugs by high school populations appears to have peaked in the late 1970s and to be decreasing at the present time, most experts still believe that drug use by American young people represents the highest level of that found in any Western developed country.
Автор: Zili Sloboda Название: Epidemiology of Drug Abuse ISBN: 1489995641 ISBN-13(EAN): 9781489995643 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Defining and Measuring Drug Abuse Behaviors.- Drug Abuse Heterogeneity and the Search for Subtypes.- Studying the Natural History of Drug Abuse.- Health, Social and Psychological Consequences of Drug Use and Abuse.- Use of Archival Data.- Sampling Issues in Drug Epidemiology.- Collecting Drug Use Data from Different Populations.- Indirect Methods to Estimate Prevalence.- Qualitative Methods in the Drug Abuse Fields.- Ethical Considerations for Drug Abuse Epidemiologic Research.- A Common Language for a Common Problem: The Developing Role of Drug Epidemiology in a Global Context.- Longitudinal Studies of Drug Use and Abuse.- Drug Abuse and the Spread of Infection.- Implications of Epidemiologic Information for Effective Drug Abuse Prevention Strategies.- The Role of Treatment Data in Studying the Epidemiology of Substance Use and Abuse.
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