Описание: Reflecting the significant developments of the past decade, this textbook explains key physical methods in modern biology. Each method is illustrated through real-world examples, alongside background information designed for both physicists and biologists, making this an ideal resource for students in biophysics at science and medical schools.
Автор: Oren M. Becker; Martin Karplus Название: Guide to Biomolecular Simulations ISBN: 9401776350 ISBN-13(EAN): 9789401776356 Издательство: Springer Рейтинг: Цена: 13549.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Molecular dynamics simulations have become instrumental in replacing our view of proteins as relatively rigid structures with the realization that they were dynamic systems, whose internal motions play a functional role.
Автор: Dikeos M. Soumpasis; Thomas M. Jovin Название: Computation of Biomolecular Structures ISBN: 3642778003 ISBN-13(EAN): 9783642778001 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Computational techniques have become an indispensable part of Molecular Biology, Biochemistry, and Molecular Design.
Автор: Fernandez Stigliano, Ariel Название: Biomolecular interfaces ISBN: 3319168495 ISBN-13(EAN): 9783319168494 Издательство: Springer Рейтинг: Цена: 10480.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The Aqueous Interface of a Soluble Protein or the Birth of Epistructural Biology.- Electrostatic Exploration of Biomolecular Interfaces: The Chemical Function of Interfacial Water.- Semiempirical Solution to the Protein Folding Problem Through a Combination of Structural and Epistructural Approaches.- Packing Defects and Protein Hydration: Dynamics of the Aqueous Interface.- Proteins in the Order-Disorder Twilight: Unstable Interfaces Promote Protein Aggregation.- Evolution of Protein Structure Degradation and Lessons for the Drug Designer.- Chemical Functionality of the Aqueous Interface in Soluble Proteins.- The Biomolecular Interface as a Selectivity Filter for Drug-Based Targeted Therapy.- Wrapping-Based Re-Engineering of an Anticancer Drug to Make it Safer.- Biomolecular Interfaces Provide Universal Markers for Drug Specificity and Personalized Medicine.- Controlling Induced Folding Through Wrapping Drug Design.- Wrapping Drug Combinations for Therapeutic Editing of Side Effects: Systems Biology Meets Wrapping Technology.- Multi-Target Control of Drug Impact: A Therapeutic Imperative in Cancer Systems Biology.- Engineering Therapeutic Alignments between Immune Response and Molecularly Targeted Cancer Treatment.- High-Level Quantum Chemistry Empowers the Wrapping Technology for Drug Design.- Epilogue.- Appendix 1. Code for Dehydron Identification.- Appendix 2. Solutions of Problems.
Описание: This lecture notes book presents how enhanced structural information of biomolecular ions can be obtained from interaction with photons of specific frequency - laser light.
Описание: Proceedings of the 1993 International Workshop on Electronics and Biotechnology Advanced held on the Isle of Elba, Italy, July 13-16, 1993
Автор: Fern?ndez Название: Physics at the Biomolecular Interface ISBN: 3319308513 ISBN-13(EAN): 9783319308517 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This bookfocuses primarily on the role of interfacial forces in understanding biologicalphenomena at the molecular scale. By providing a suitable statisticalmechanical apparatus to handle the biomolecular interface, the book becomesuniquely positioned to address core problems in molecular biophysics. Ithighlights the importance of interfacial tension in delineating a solution tothe protein folding problem, in unravelling the physico-chemical basis ofenzyme catalysis and protein associations, and in rationally designingmolecular targeted therapies. Thus grounded in fundamental science, the bookdevelops a powerful technological platform for drug discovery, while it is setto inspire scientists at any level in their careers determined to address themajor challenges in molecular biophysics.Theacknowledgment of how exquisitely the structure and dynamics of proteins and theiraqueous environment are related attests to the overdue recognition thatbiomolecular phenomena cannot be effectively understood without dealing withinterfacial behaviour. There is an urge to grasp how biologically relevantbehaviour is shaped by the structuring of biomolecular interfaces and howinterfacial tension affects the molecular events that take place in the cell.This book squarely addresses these needs from a physicist perspective.Thebook may serve as a monograph for practitioners and, alternatively, as anadvanced textbook. Fruitful reading requires a background in physical chemistryand some basics in biophysics. The selected problems at the end of the chaptersand the progression in conceptual difficulty make it a suitable textbook for agraduate level course or an elective course for seniors majoring in chemistry,physics, biomedical engineering or related disciplines.
Автор: Artem Ryabov Название: Stochastic Dynamics and Energetics of Biomolecular Systems ISBN: 3319271873 ISBN-13(EAN): 9783319271873 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These geometries serve, for example, to model ion transport through narrow channels in cell membranes or a Brownian particle diffusing in an optical trap, now a paradigm for both theory and experiment.The work is exceptional in obtaining explicit analytically formulated answers to such realistic, experimentally relevant questions.
Описание: This lecture notes book presents how enhanced structural information of biomolecular ions can be obtained from interaction with photons of specific frequency - laser light.
Автор: Gustavo Garc?a G?mez-Tejedor; Martina Christina Fu Название: Radiation Damage in Biomolecular Systems ISBN: 9400795823 ISBN-13(EAN): 9789400795822 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers advances in radiation protection, including research on radiation-induced damage at the molecular level, radiation damage modelling, biomedical aspects of radiation effects and much more. Includes the work of research groups worldwide.
Автор: Barrick Название: Biomolecular Thermodynamics: From Theory to Application ISBN: 1439800197 ISBN-13(EAN): 9781439800195 Издательство: Taylor&Francis Рейтинг: Цена: 17609.00 р. Наличие на складе: Поставка под заказ.
Описание: This book introduces the concepts and practical tools necessary to understand the behavior of biological macromolecules at a quantitative level, going beyond theory to explain in detail how the equations are applied to the analysis of experimental measurements. An emphasis on real-world applications is a continued throughout the book.
Описание: With chapters contributed by leading scientists from 20 research groups worldwide, this volume provides an overview of modern computer-based techniques to compute the structure, properties, and dynamics of biomolecules and biomolecular processes.
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