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PAS Proteins: Regulators and Sensors of Development and Physiology, Stephen T. Crews


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Автор: Stephen T. Crews
Название:  PAS Proteins: Regulators and Sensors of Development and Physiology
ISBN: 9781461351153
Издательство: Springer
Классификация:






ISBN-10: 1461351154
Обложка/Формат: Paperback
Страницы: 263
Вес: 0.39 кг.
Дата издания: 21.10.2012
Язык: English
Размер: 234 x 156 x 15
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

The subject of this volume is a comprehensive examination of the biochemistry and biology of all classes of known PAS proteins, with the intention that readers will find insight into their own work and ideas from study of the multitude of PAS protein functions. PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.

Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders, and (6) mental health disorders such as social interactions and learning.

PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.




Advancing Development of Synthetic Gene Regulators

Автор: Anandhakumar Chandran
Название: Advancing Development of Synthetic Gene Regulators
ISBN: 9811065462 ISBN-13(EAN): 9789811065460
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome.

Bone Morphogenetic Proteins: Systems Biology Regulators

Автор: Slobodan Vukicevic; Kuber Sampath
Название: Bone Morphogenetic Proteins: Systems Biology Regulators
ISBN: 3319475053 ISBN-13(EAN): 9783319475059
Издательство: Springer
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Цена: 25155.00 р.
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MicroRNAs: Key Regulators of Oncogenesis

Автор: Sadegh Babashah
Название: MicroRNAs: Key Regulators of Oncogenesis
ISBN: 3319037242 ISBN-13(EAN): 9783319037240
Издательство: Springer
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Цена: 26122.00 р.
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Описание: Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state.

Novel Apoptotic Regulators in Carcinogenesis

Автор: George G. Chen; Paul B.S. Lai
Название: Novel Apoptotic Regulators in Carcinogenesis
ISBN: 9400794932 ISBN-13(EAN): 9789400794931
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Our recent understanding of the cellular and molecular defects and the regulation of the apoptotic signalling pathways has resulted in rationally designed anticancer strategies and the development of novel agents that regulates apoptosis. A comprehensive review of all apoptotic-related anticancer therapies is not the purpose of this book. However, in the volume of this book with 11 chapters, we have described a number of novel apoptotic regulators that have shown promising value and also great feasibility for cancer treatment. These novel agents either occur naturally or are chemically synthesized. While we are excited about the discovery and development of these novel apoptotic regulators as potential anticancer agents, a degree of caution should be always borne in mind when interpreting the success of preclinical pro-apoptotic candidates since potential problems inevitably lie ahead. These problems usually include target specificity, unanticipated toxicity, compound stability, formulation issues, pharmacokinetic and pharmacodynamic profiles. Nevertheless, we believe that this collection of 11 chapters by established leaders in the area of apoptosis will be of great interest to not only academics working in the field of cancer research and apoptosis but also pharmaceutical and pharmacological industries that . We are looking forward to the further development to push these potential agents toward clinical stage.

Extracellular ATP and adenosine as regulators of endothelial cell function

Автор: Evgenia Gerasimovskaya; Elzbieta Kaczmarek
Название: Extracellular ATP and adenosine as regulators of endothelial cell function
ISBN: 9400796803 ISBN-13(EAN): 9789400796805
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication.

Herbicide Resistance — Brassinosteroids, Gibberellins, Plant Growth Regulators

Автор: G. Adam; S.O. Duke; D. Gross; M. Lischewski; V. Ma
Название: Herbicide Resistance — Brassinosteroids, Gibberellins, Plant Growth Regulators
ISBN: 3642487890 ISBN-13(EAN): 9783642487897
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Chemistry of Plant Protection, Volume 7, provides critical review articles on new aspects of herbicide resis- tance, serving the needs of research scientists, pesticide manufacturers, government regulators, agricultural practitioners.

MicroRNAs: Key Regulators of Oncogenesis

Автор: Sadegh Babashah
Название: MicroRNAs: Key Regulators of Oncogenesis
ISBN: 3319376136 ISBN-13(EAN): 9783319376134
Издательство: Springer
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Цена: 20896.00 р.
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Описание: Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state.


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