Epstein-Barr Virus and Human Disease · 1990, D. V. Ablashi; A. T. Huang; J. S. Pagano; G. R. Pe

Автор: D. V. Ablashi; A. T. Huang; J. S. Pagano; G. R. Pe
Название: Epstein-Barr Virus and Human Disease · 1990
ISBN: 0896032213 ISBN-13(EAN): 9780896032217
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Описание: The Epstein-Barr virus (EBV), isolated in 1966, continues to draw worldwide attention as an important human pathogen. The second international symposium was held in St. Petersburg, Florida, in 1986, and was attended by approximately twice as many partici- pants as attended the Loutraki meeting.

Автор: D. V. Ablashi; A. Faggioni; G. R. F. Krueger; J. S
Название: Epstein-Barr Virus and Human Disease • 1988
ISBN: 0896031659 ISBN-13(EAN): 9780896031654
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Описание: The major target cell for EBV infection has now been conclusively identified as the complement receptor-type 2 (CR2), the Cd/Cdg 3 3 receptor on B lymphocyte. It is apparent, however, that other cells also can become infected by EBV, such as epithelial cells in the parotid gland and other epithelial cells in the upper respiratory tract.

Автор: D. V. Ablashi; A. Faggioni; G. R. F. Krueger; J. S
Название: Epstein-Barr Virus and Human Disease • 1988
ISBN: 1461288525 ISBN-13(EAN): 9781461288527
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Описание: The major target cell for EBV infection has now been conclusively identified as the complement receptor-type 2 (CR2), the Cd/Cdg 3 3 receptor on B lymphocyte. It is apparent, however, that other cells also can become infected by EBV, such as epithelial cells in the parotid gland and other epithelial cells in the upper respiratory tract.

Автор: K. Takada
Название: Epstein-Barr Virus and Human Cancer
ISBN: 3642625681 ISBN-13(EAN): 9783642625688
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Описание: Many malignancies such as T/NK cell lymphoma, AIDS-associated B-cell lymphoma, gastric carcinoma and Hodgkin`s disease have been causally linked to EBV. The development of molecular biology technique has allowed us to study the roles of individual EBV genes that act in the maintenance and disruption of EBV latency.

Автор: Wilson Joanna B., May Gerhard H. W.
Название: Epstein-Barr Virus Protocols
ISBN: 0896036901 ISBN-13(EAN): 9780896036901
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Описание: Joanna Wilson and Gerhard May have assembled a collection of the key molecular biology protocols used in the analysis of Epstein-Barr virus (EBV), along with a series of valuable immunology, cell biology, and transgenic mouse protocols. These readily reproducible techniques include methods for gene expression with mini-EBV plasmids, for expression analysis by FISH, for EBV detection and quantitation, and for cell proliferation and death assays. In addition, there are EBV-based vectors, an up-to-date map of EBV, a comprehensive table of available latent protein antisera, and assays from in vitro to cell to organ to organism levels. Timely and highly practical, Epstein-Barr Virus Protocols provides powerful tools for elucidating the life cycle of EBV and its host interactions, work that promises the emergence of major new treatments and cures for EBV associated diseases, including several forms of human cancer.

Автор: Janos Minarovits; Johann Helmut Niller
Название: Epstein Barr Virus
ISBN: 1493966537 ISBN-13(EAN): 9781493966530
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Описание: This volume explores data from the applications of molecular biological methods and the applications of recent immunological and cytogenetic methods in Epstein-Barr Virus (EBV) that will offer readers possible new solutions to the unresolved problems in the EBV field. Chapters in this book cover topics such as: viral life cycle, latency, EBV-associated diseases and EBV diagnostics; in vitro methods including organotypic cultures for the analysis of EBV-epithelial cell interactions; identification of the interacting viral and cellular proteins using affinity purification-mass spectrometry methods; 3D telomere FISH; transcription analysis using high-throughput RNA sequencing, qPCR and nuclear run-on assay; analysis of viral and cellular microRNAs; isolation and characterization of exosomes and the assessment of their function; characterization of the viral genome by terminal repeat analysis and sequencing; the use of chromatin immunoprecipitation coupled sequencing (ChIP-Seq) for the analysis of Zta-DNA interactions; epigenetic analysis by bisulfite sequencing and ChIP; novel in vivo models for the study of EBV infection; and how immunological, virological, tissue culture and molecular methods can be combined to yield Good Manufacturing Practice-compliant EBV-specific T cells for the immunotherapy of EBV-associated post-transplant lymphoproliferative diseases (PTLD). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Epstein Barr-Virus: Methods and Protocols is a valuable resource for anyone who is interested in this fascinating and evolving field.

Название: Epstein barr virus
ISBN: 3319228218 ISBN-13(EAN): 9783319228211
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Описание: Epstein Barr Virus Volume 1

Автор: M. A. Epstein; B. G. Achong
Название: The Epstein-Barr Virus
ISBN: 3642672388 ISBN-13(EAN): 9783642672385
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Описание: Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole- cular virology, since it is the cause of infectious mononu- cleosis and also the first human cancer virus, etiologically related to endemic Burkitt`s lymphoma and probably to nasopharyngeal carcinoma.

Автор: Christian M?nz
Название: Epstein Barr Virus Volume 2
ISBN: 3319228331 ISBN-13(EAN): 9783319228334
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Описание: Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.

Автор: Christian M?nz
Название: Epstein Barr Virus Volume 2
ISBN: 3319358340 ISBN-13(EAN): 9783319358345
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Описание:

Preface.- EBV latency.- Chap. 1. EBNA1 - Lori Frappier, University of Toronto, Canada.- Chap. 2. EBNA2 and its coactivator EBNA-LP - Bettina Kempkes, Helmholtz Center Munich, Germany, and Paul D. Ling, Baylor College of Medicine, Houston, USA.- Chap. 3. The EBNA3 family: two oncoproteins and a tumour suppressor that are central to the biology of EBV in B cells- Martin J. Allday, Quentin Bazot and Robert E. White, Imperial College London, UK. Chap. 4. The latent membrane protein 1 (LMP1) - Arnd Kieser and Kai R. Sterz, Helmholtz Center Munich, Germany. Chap. 5. Latent membrane protein 2 (LMP2) - Osman Cen and Richard Longnecker, Northwestern University, Chicago, USA. Chap. 6. EBV non-coding RNAs - Rebecca L. Skalsky and Bryan R. Cullen, Duke University, Durham, USA.- E. Lytic EBV infection.- 7. Viral entry - Liudmila S. Chesnokova, Ru Jiang¹ and Lindsey M. Hutt-Fletcher, Louisiana State University, Shreveport, USA.- Chap. 8. Epstein Barr virus lytic cycle reactivation - Jessica McKenzie and Ayman El-Guindy, Yale University, New Haven, USA.- Immune responses to EBV.- Chap. 9. Innate immune recognition of EBV - Anna Lьnemann and David Nadal, University of Zьrich, Switzerland and Martin Rowe, University of Birmingham, UK.- Chap. 10. Epstein-Barr virus specific humoral immune responses in health and disease - Jaap M. Middeldorp, VU Medical Center, Amsterdam, The Netherlands.- Chap. 11. T cell responses to EBV - Andrew D. Hislop and Graham S. Taylor, University of Birmingham, UK.- Chap. 12. Immune evasion by Epstein Barr virus - Maaike E. Ressing, Michiel van Gent, Anna M. Gram, Marjolein Hooykaas, Sytse Piersma and Emmanuel Wiertz, Utrecht Medical Center, The Netherlands.- Animal models of EBV infection.- Chap. 13. Non-human primate lymphocryptoviruses: past, present, and future- Janine Mьhe and Fred Wang, Harvard University, Boston, USA. Chap.14. EBV infection of mice with reconstituted human immune system components -

Автор: Christian M?nz
Название: Epstein Barr Virus Volume 1
ISBN: 3319371770 ISBN-13(EAN): 9783319371771
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Описание: Preface.- History.- Chap. 1 Why and How Epstein-Barr Virus was discovered 50 years ago - Anthony Epstein, University of Oxford, UK.- Chap. 2. Tumor associations of EBV - historical perspectives - George Klein, Karolinska Institutet, Stockholm, Sweden.- Chap. 3. EBV-specific immune response: early research and personal reminiscences - Denis J. Moss and Viviana P. Lutzky, Queensland Institute of Medical Research, Brisbane, Australia.- Virus genetics and epigenetics.- Chap. 4. Epstein Barr virus strain variation - Paul J. Farrell, Imperial College, London, UK.- Chap. 5. Chromatin Structure of Epstein-Barr Virus Latent Episomes - Paul M. Lieberman, University of Pennsylvania, Philadelphia, USA.- Chap. 6. The epigenetic life cycle of Epstein-Barr virus - Wolfgang Hammerschmidt, Helmholtz Center Munich, Germany. Chap. 7. Epstein-Barr virus: from the detection of sequence polymorphisms to the recognition of viral types - Regina Feederle, Olaf Klinke, Anton Kutikhin, Remy Poirey, Ming-Han Tsai and Henri-Jacques Delecluse, German Cancer Research Center, Heidelberg, Germany.- Viral infection and associated diseases.- Chap. 8. EBV persistence - introducing the virus - David A. Thorley-Lawson, Tufts University, Boston, USA.- Chap. 9. Infectious mononucleosis - Samantha K. Dunmire, Kristin A. Hogquist and Henry H. Balfour, Jr., University of Minnesota, Minneapolis, USA.- Chap. 10. Primary immunodeficiencies associated with EBV disease - Jeffrey I. Cohen, National Institutes of Health, Bethesda, USA.- Chap. 11. Burkitt's lymphoma - Rosemary Rochford and Ann M. Moormann, University of Massachusetts, Worcester, and Upstate University of New York, Syracuse, USA.- Chap. 12. Contribution of the Epstein-Barr virus to the pathogenesis of Hodgkin lymphoma - Paul Murray and Andrew Bell, University of Birmingham, UK.- Chap. 13. The role of EBV in the pathogenesis of diffuse large B cell lymphoma - Jane A. Healy and Sandeep S. Dave, Duke University, Raleigh, USA.- Chap. 14. Nasopharyngeal carcinoma: an evolving role for the Epstein Barr virus - Nancy Raab-Traub, University of North Carolina, Chapel Hill, USA.-Chap. 15. EBV and autoimmunity - Alberto Ascherio and Kassandra Munger, Harvard University, Boston, USA.- Index.

Автор: P.H. Levine; D.V. Ablashi; G.R. Pearson; S.D. Kott
Название: Epstein-Barr Virus and Associated Diseases
ISBN: 1461296412 ISBN-13(EAN): 9781461296416
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Описание: Proceedings of the first international symposium on Epstein-Barr Virus-Associated Malignant Diseases (Loutraki, Greece, September 24-28, 1984)