Автор: Timothy R. Hughes Название: A Handbook of Transcription Factors ISBN: 9400736045 ISBN-13(EAN): 9789400736047 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written from a genome-based perspective, this volume provides an objective overview of transcription factor biochemistry. Topics include known transcription factor classes, origins and evolution of transcription factor types, and mechanisms of interaction with chromatin.
Автор: Robert N. Eisenman Название: The Myc/Max/Mad Transcription Factor Network ISBN: 3642421415 ISBN-13(EAN): 9783642421419 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the “big picture” and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.
Автор: Takashi Ohyama Название: DNA Conformation and Transcription ISBN: 1489995072 ISBN-13(EAN): 9781489995070 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Despite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differential expression of genes is enabled in a given cell type. Exploring and answering these questions constitutes one of the next frontiers in the 21st century.
We are just beginning to appreciate how Multifarious DNA structures provide additional structural and functional dimensions to chromatin organization and gene expression. DNA Conformation and Transcription is the first book that compiles the fruits of the studies that have been performed to date to solve the riddle 'written' in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code."
Автор: Etsuko Miyamoto-Sato; Hiroyuki Ohashi; Hirotaka Sa Название: Transcription Factor Regulatory Networks ISBN: 1493908049 ISBN-13(EAN): 9781493908042 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Transcription Factor Regulatory Methods details various techniques ranging from cutting-edge to general techniques use to study transcription factor regulatory networks.
Автор: Etsuko Miyamoto-Sato; Hiroyuki Ohashi; Hirotaka Sa Название: Transcription Factor Regulatory Networks ISBN: 1493954458 ISBN-13(EAN): 9781493954452 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Transcription Factor Regulatory Methods details various techniques ranging from cutting-edge to general techniques use to study transcription factor regulatory networks.
Автор: Martin J. Tymms Название: Transcription Factor Protocols ISBN: 1617370819 ISBN-13(EAN): 9781617370816 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: General initiation factors are involved in positioning RNA polymerase II on the core promoter, but the complex - teraction of these proteins and transcriptional activators binding to DNA e- ments outside the core promoter regulate the rate of transcriptional initiation.
Автор: John E.G. McCarthy; Mick F. Tuite Название: Post-Transcriptional Control of Gene Expression ISBN: 3642751415 ISBN-13(EAN): 9783642751417 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO/CEC Advanced Research Workshop on Post-Transcriptional Control of Gene Expression, held in Goslar, FRG, April 6-12, 1990
Автор: Ales Vancura Название: Transcriptional Regulation ISBN: 1493958542 ISBN-13(EAN): 9781493958542 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book exemplifies recent advances in transcriptional regulation with a set of key cutting-edge protocols from around the world. It explores topics ranging from transcription factors to pre-initiation complex (PIC) assembly and RNA synthesis and regulation.
Описание: During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and megakaryocytes.
Автор: K.M.J. Menon, PhD; Aaron Goldstrohm, PhD Название: Post-transcriptional Mechanisms in Endocrine Regulation ISBN: 3319251228 ISBN-13(EAN): 9783319251226 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones.
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