Автор: Young Je Yoo; Yan Feng; Yong-Hwan Kim; Camila Flor Название: Fundamentals of Enzyme Engineering ISBN: 9402410244 ISBN-13(EAN): 9789402410242 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Samira Hosseini; Patricia V?zquez-Villegas; Marco Название: Enzyme-linked Immunosorbent Assay (ELISA) ISBN: 9811067651 ISBN-13(EAN): 9789811067655 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers comprehensive information on all aspects of ELISA, starting with the fundamentals of the immune system. Accordingly, the book provides cutting-edge information on integrated platforms such as ELISpot, plasmonic ELISAs, sphere-/bead-based ELISAs, paper-/fiber-based ELISAs and ELISA in micro-devices.
Автор: V.A. Najjar Название: Enzyme Induction and Modulation ISBN: 0898385830 ISBN-13(EAN): 9780898385830 Издательство: Springer Рейтинг: Цена: 38992.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In addition to performing its prime function as a vehicle for scientific communications of varied colora- tions, Molecular and Cellular Biochemistry is again focusing on two subjects which it treats in depth. One of these is a book issue dealing with the transglutaminase reaction. The other is this issue that deals with induction and modulation of enzymes. This is a very broad subject that calls for broader coverage than could be included in one book issue. However, I have elected to include only certain contributions that serve as general examples of the principles involved. There are six articles on enzyme regulation in hepatocyte culture. These include arginase and argino-succi- nate synthetase, y-glutamyl transferase and plasminogen activitor. Other regulatory enzymes that are discussed are protein kinases, 2,3-bisphosphoglycerate synthetases, carbamoyl phosphate synthetase, heme oxygenase, cytochrome P-450, tyrosine hydroxylase, fatty acid synthetase, acetyl eoA carboxylase, among others. Also included is the regulation of several enzyme messengers RNAs. As in the past, subscribers to the journal will receive this double volume as a continuation of regular issues of the journal Molecular and Cellular Biochemistry. This double volume will also be available separately in the form of a book issue to interested readers through Martinus Nijhoff Publishers. v.A. Najjar Part I Molecular and Cellular Biochemistry 53;54,11-21 (1983). (c) 1983, Martinus 1\ ij hoff Publishers. Boston. Printed in The Netherlands.
Описание: This book addresses issues arising from discharge of effluents from sugar industry on to surrounding land or into a water body such as physicochemical properties of soil, changes in the micro flora, quantification of soil enzyme activities as influenced by effluents. Disposal of effluents without neutralization has become general practice. These effluents are chemically heterogeneous, contain organic and inorganic pollutants including, sugar baggage, molasses, carbonates, bicarbonates. The impact of sugar industry effluents on microbial activities in terrestrial ecosystem is scanty. There is also significant interest in the study of soil enzymes because such effect reflects the potential capacity of a soil to perform certain biological transformation of soil fertility.
Автор: Jean-Pierre Saint-Jeannet Название: Neural Crest Induction and Differentiation ISBN: 1461497612 ISBN-13(EAN): 9781461497615 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.
Автор: Colin Suckling Название: Enzyme Chemistry ISBN: 9401073171 ISBN-13(EAN): 9789401073172 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the first edition of this book was going through the publication process, a revolution was taking place in the technologies available for the study of enzymes. The second edition of `Enzyme Chemistry, Impact and Applications` takes on board these new develop- ments whilst maintaining the overall aims and views of the first edition.
Автор: Antonio Baici Название: Kinetics of Enzyme-Modifier Interactions ISBN: 3709114012 ISBN-13(EAN): 9783709114018 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The kinetic mechanisms by which enzymes interact with inhibitors and activators, collectively called modifiers, are scrutinized and ranked taxonomically into autonomous species in a way similar to that used in the biological classification of plants and animals. The systematization of the mechanisms is based on two fundamental characters: the allosteric linkage between substrate and modifier and the factor by which a modifier affects the catalytic constant of the enzyme. Combinations of the physically significant states of these two characters in an ancestor-descendant-like fashion reveal the existence of seventeen modes of interaction that cover the needs of total, partial and fine-tuning modulation of enzyme activity. These interactions comprise five linear and five hyperbolic inhibition mechanisms, five nonessential activation mechanisms and two hybrid species that manifest either hyperbolic inhibition or nonessential activation characteristics depending on substrate concentration. Five essential activation mechanisms, which are taxonomically independent of the mentioned basic species, complete the inventory of enzyme modifiers. Often masked under conventional umbrella terms or treated as anomalous cases, all seventeen basic inhibition and nonessential activation mechanisms are represented in the biochemical and pharmacological literature of this and the past century, either in the form of rapid or slow-onset reversible interactions, or as irreversible modification processes. The full potential of enzyme inhibitors and activators can only be appreciated after elucidating the details of their kinetic mechanisms of action exploring the entire range of physiologically significant reactant concentrations. This book highlights the wide spectrum of allosteric enzyme modification in physiological occurrences as well as in pharmacological and biotechnological applications that embrace simple and multiple enzyme-modifier interactions. The reader is guided in the journey through this still partly uncharted territory with the aid of mechanistically-oriented criteria aimed at showing the logical way towards the identification of a particular mechanism.
Описание: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with mo than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Описание: This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.
Автор: Dietmar Schomburg; D?rte Stephan Название: Enzyme Handbook 9 ISBN: 3642489877 ISBN-13(EAN): 9783642489877 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent progress on enzyme immobilisation, enzyme production, coenzyme re- generation and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. The enzymes in this Handbook are arranged according to the Enzyme Com- mission list of enzymes.
Автор: Judith Klinman; Sharon Hammes- Schiffer Название: Dynamics in Enzyme Catalysis ISBN: 3642440738 ISBN-13(EAN): 9783642440731 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Christopher M. Cheatum and Amnon Kohen, Relationship of Femtosecond–Picosecond Dynamics to Enzyme-Catalyzed H-Transfer. Cindy Schulenburg and Donald Hilvert, Protein Conformational Disorder and Enzyme Catalysis. A. Joshua Wand, Veronica R. Moorman and Kyle W. Harpole, A Surprising Role for Conformational Entropy in Protein Function. Travis P. Schrank, James O. Wrabl and Vincent J. Hilser, Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations. Buyong Ma and Ruth Nussinov, Structured Crowding and Its Effects on Enzyme Catalysis. Michael D. Daily, Haibo Yu, George N. Phillips Jr and Qiang Cui, Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations. Karunesh Arora and Charles L. Brooks III, Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase. Steven D. Schwartz, Protein Dynamics and the Enzymatic Reaction Coordinate.
Автор: S.S. Deshpande Название: Enzyme Immunoassays ISBN: 1461284953 ISBN-13(EAN): 9781461284956 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since the classical work of Rosalyn Yalow and Solomon Berson on the radioim- munoassay of insulin in the late 1950s, which so brilliantly opened new domains in the diagnostics sector, immunoassays have been well received as a diagnostic and research tool in several disciplines of life sciences. The economics, rapidity, sensitivity, specificity, and the easy-to-use approach of immunodiagnostic tests are widely recognized, and have had a tremendous impact on clinical, agricultural, food, veterinary, and environmental diagnostics. At present, in the clinical diag- nostic sector alone, immunoassay products command an annual worldwide mar- ket value in excess of U. S. $10 billion, which is expanding by about 10% per annum. The recent trend toward increasing demand for automation of immunoassays and stable reagents clearly shows a definitive shift to nonisotopic immunoassay systems on a large scale. Historically, enzyme immunoassays have been in a prime position for in-house applications, primarily because of the easy access to inex- pensive measuring equipment as well as to a vast body of literature on labeling techniques and applications. The recent popularity with the general public of sev- eral over-the-counter immunoassay products based on this technology, such as glucose level kits for diabetics, cholesterol screening tests, and pregnancy detec- tion test kits, is quite evident.
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