Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis, Paolo Beck-Peccoz

Автор: Felix G. Sulman; M. Ben-David
Название: Hypothalamic Control of Lactation
ISBN: 3642462359 ISBN-13(EAN): 9783642462351
Издательство: Springer
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Описание: The contents of this monograph "Hypothalamic Control of Lacta- tion" are the result of studies by a nine-man team which has worked together for nine years. The topic is so fascinating that new research students are attracted to it every year, and the circle is growing steadily. This is, in fact, part of a much more extensive research field to which our Department is applying itself at present, viz. "Hypo- thalamic Pharmacology." Our work in this sphere was made possible by a generous grant from the United States Department of Agriculture, which helped us during the first 5 years of research with Grant No. FG-IS-147, Project No. A10-AH-3, and recently with another grant for a further 5-year period, No. FG-IS-259, Project No. A10-AH-33. Our thanks are due to Dr. JOEL BITMAN, Hormone Physiology Leader of the USDA Agri- cultural Research Service at Beltsville, Md., the sponsor of this research. As this monograph contains mainly references connected with our own work, the reader who wishes to make a survey of lactation should study the references cited in the bibliography, such as COWIE (1961, 1966), COWIE and FOLLEY (1957, 1961), FOLLEY (1952, 1956), JACOB- SOHN (1961), LYONS and DIXON (1966), MEITES (1959a, 1961, 1966), MEITES and NICOLL (1966).

Автор: Reglodi
Название: Pituitary Adenylate Cyclase Activating Polypeptide — PACAP
ISBN: 3319351338 ISBN-13(EAN): 9783319351339
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Описание: The first comprehensive book to cover all aspects of the last 25 years of PACAP (pituitary adenylate cyclase activating polypeptide) research, this book contains contributions from virtually all the leading researchers in the field, and addresses some of the following topics: evolutionary aspects of PACAP, distribution and occurrence of PACAP and its receptors, hormonal effects of PACAP, intracellular signaling, effects on cellular proliferation and differentiation, protective effects of PACAP, behavioral effects of PACAP, developmental aspects of PACAP, other physiological effects of PACAP (cardiovascular, thermoregulatory), human studies, drug design, metabolism and transport. This compendium can serve as an important reference for researchers and students in PACAP research and can also be a thorough introduction for those in related fields.

Автор: C.R. Kannan
Название: The Pituitary Gland
ISBN: 1461290325 ISBN-13(EAN): 9781461290322
Издательство: Springer
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Описание: This first volume in Clinical Surveys in Endocrinology, The Pituitary Gland, has been written with but one purpose in mind: to integrate the current knowledge in this dynamic field with the existing body of information already available to the clinician.

Автор: Michael C. Sheppard; Paul M. Stewart
Название: Pituitary Disease
ISBN: 1461354013 ISBN-13(EAN): 9781461354017
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Описание: Pituitary Disease brings together an international panel of experts who summarize the most recent and exciting advances in the diagnosis and treatment of pituitary disease. clinical scenarios underpinning each type of pituitary tumor as well as their diagnosis and treatment.

Название: Hormones and Hormone System
ISBN: 3319150596 ISBN-13(EAN): 9783319150598
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Описание: This book focuses on hormones, and on how they are produced in very diverse regions of the body in humans and animals. The book addresses the different classes of hormones: protein/peptides hormones, steroids and juvenile hormones and hormones like catecholamines, thyroid hormones and melatonin.

Автор: Eliza B. Geer
Название: The Hypothalamic Pituitary Adrenal Axis in Health and Disease
ISBN: 3319459481 ISBN-13(EAN): 9783319459486
Издательство: Springer
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Описание: Cushing?s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.

Автор: Kenneth W. McKerns
Название: Hormonal Control of the Hypothalamo-Pituitary-Gonadal Axis
ISBN: 1468499629 ISBN-13(EAN): 9781468499629
Издательство: Springer
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Описание: The eleventh monograph and meeting of the Foundation on "Hormon- al Control of the Hypothalamo-Pituitary-Gonadal Axis" was held in October 1983 at the Weizmann Institute of Science. I saw pictures of this area when Dr. Chaim Weizmann founded in 1934, the Daniel Sieff Research Institute, the forerunner of the Weizmann In- stitute.

Автор: Noriyuki Koibuchi; Paul M. Yen
Название: Thyroid Hormone Disruption and Neurodevelopment
ISBN: 1493937359 ISBN-13(EAN): 9781493937356
Издательство: Springer
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Описание: Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a “repressor” of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanisms that create each abnormal phenotype are not fully understood. ?

Автор: E. V. Naumenko
Название: Central Regulation of the Pituitary-Adrenal Complex
ISBN: 1468416162 ISBN-13(EAN): 9781468416169
Издательство: Springer
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Описание: This monograph gives an up-to-date account of the original results of the author`s research in the complex field of the central control over relationships which have become established in the course of evolution between the hypothalamus and the pituitary gland.

Автор: M. Mu Huo Teng; Jean-Francois Bonneville; F. Catti
Название: Computed Tomography of the Pituitary Gland
ISBN: 3642703771 ISBN-13(EAN): 9783642703775
Издательство: Springer
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Описание: The present volume is the results of 6 years` work by our team, during which time 2300 CT scans of the pituitary region were carried out.

Автор: Kalmon D. Post
Название: The Pituitary Adenoma
ISBN: 1468436708 ISBN-13(EAN): 9781468436709
Издательство: Springer
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Описание: The idea for this book developed as an outcome of a multidisciplinary sym- posium entitled "Pituitary Adenoma Update" that was held at Tufts-New En- gland Medical Center in April 1977.

Автор: Isabel Varela-Nieto; Julie Ann Chowen
Название: The Growth Hormone/Insulin-Like Growth Factor Axis during Development
ISBN: 1461498112 ISBN-13(EAN): 9781461498117
Издательство: Springer
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Описание: Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.