Breast Cancer Immunodiagnosis and Immunotherapy, Roberto Ceriani
Автор: Yotnda Название: Immunotherapy of Cancer ISBN: 1607617854 ISBN-13(EAN): 9781607617853 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. It includes coverage of pre-clinical models for cancer immunotherapy.
Автор: Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642141358 ISBN-13(EAN): 9783642141355 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Автор: Ludewig Burkhard, Hoffmann Matthias W. Название: Adoptive Immunotherapy / Methods and Protocols ISBN: 1588294064 ISBN-13(EAN): 9781588294067 Издательство: Springer Рейтинг: Цена: 24456.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy.
Автор: Zhang Название: Progress in Cancer Immunotherapy ISBN: 9401775532 ISBN-13(EAN): 9789401775533 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Thisbook provides readers an extensive overview of recent progress in basicand clinical research on cancer immunotherapy. Thanks to rapid advances inmolecular biology and immunology, it has become increasingly evident thatcancer growth is influenced by host immune responses. With the success of anumber of clinical trials, immunotherapy has become a promising treatmentmodality of cancer. This book covers five major topics, including monoclonalantibodies, biological response modifiers, cancer vaccines, adoptive cellulartherapy and oncolytic viruses. It also examines the combination of differentimmune strategies as well as the combination of immunotherapy with othertreatments to increase anti-tumor effects. Throughthecomprehensive discussion of the topic, the book sheds valuable new light on thetreatment of tumors.
Автор: Andreas Radbruch; Hans-Dieter Volk; Khusru Asadull Название: Immunotherapy in 2020 ISBN: 3642420850 ISBN-13(EAN): 9783642420856 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume features contributions from participants of the ESRF symposium on Immunotherapy in 2020 Visions and Trends for Targeting Inflammatory Diseases held in Potsdam near Berlin, Germany, in October 2006. The symposium presentations covered the main mechanisms of immunoregulation.
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Автор: George C. Prendergast Название: Cancer Immunotherapy, ISBN: 0123942969 ISBN-13(EAN): 9780123942968 Издательство: Elsevier Science Рейтинг: Цена: 16169.00 р. Наличие на складе: Поставка под заказ.
Описание: There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles.
Автор: Glenn Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642267882 ISBN-13(EAN): 9783642267888 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer Immunotherapy discusses tumor-immune interactions in several human cancers. The text proposes an integrated scheme of the impact of local immune reactions on clinical outcome, and illustrates various aspects of this complexity.
Автор: Britten Название: Cancer Immunotherapy Meets Oncology ISBN: 3319051032 ISBN-13(EAN): 9783319051031 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Xiang-Yang Wang Название: Immunotherapy of Cancer,128 ISBN: 0128023163 ISBN-13(EAN): 9780128023167 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology.
Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
Название: Immunotherapy of cancer ISBN: 4431550305 ISBN-13(EAN): 9784431550303 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy has been investigated worldwide as the fourth line of cancer treatment after the standard treatments of surgery, chemotherapy, and radiotherapy. The progress in fundamental understanding of tumor immunology and the recent advances in clinical trials have opened new avenues with a cancer vaccine in 2010 and immunocheckpoint modulation in 2011, with their approval already granted in the United States. Today, there are no doubts, even among experts in cancer chemotherapy and radiotherapy, that the immune system plays a vital role in tumor eradication. Following American approval, many clinical trials of cancer immunotherapy are being conducted. With this book the reader will readily understand the paradigm shift in cancer treatment and will realize the importance of cancer immunotherapy. The great value of immunotherapy will be obvious, not only for tumor shrinkage but for prolonging patient survival.
Автор: Rong-Fu Wang Название: Innate Immune Regulation and Cancer Immunotherapy ISBN: 1489985905 ISBN-13(EAN): 9781489985903 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. This book discusses recent progress in innate immunity and Treg cells, and the regulation of innate immunity through Toll-like receptor (TLR) signalling.
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