Retinal Degenerations, Matthew M. LaVail; Joe G. Hollyfield; Robert E. An
Автор: Joyce Tombran-Tink; Colin J. Barnstable Название: Retinal Degenerations ISBN: 1493960989 ISBN-13(EAN): 9781493960989 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For centuries, humans have tried to explain the complex process of vision and find effective treatments for eye diseases. Perhaps the oldest surviving record of ancient ophthalmic practices is the Babylonian code of Hammurabi that over 4000 years ago, mentioned fees for eye surgery—and penalties for unsuccessful operations that led to loss of the eye. Babylonian medicine was controlled by priests who directed the work of skilled surgeons. The earliest records of Egyptian medicine date from almost the same time. The Ebers Papyrus, dating back to more than 3500 years ago is a superbly preserved document in which a section outlines a relatively advanced system of diagnosis and treatment of various ocular pathologies. The text reveals that ancient Greek and Egyptian physicians prescribed “liver juice” for night blindness. This was obtained from roasted and crushed ox liver. We now know that their prescription contained a remarkable amount of vitamin A. It was only within the last century, however, that we have recognized the importance of vitamin A to the function of photoreceptors and visual acuity and that its deficiency can result in night blindness. Egyptian ophthalmological practices were held in high esteem in the ancient world and so were their medical institutes, called “peri-ankh,” which existed since the first dynasty. Herodotus, the fifth century BC Greek historian, comments on the specialization of the physicians: “Each physician treats just one disease.
Автор: Bernhard H.F. Weber; THOMAS LANGMANN Название: Retinal Degeneration ISBN: 1493959697 ISBN-13(EAN): 9781493959693 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book offers methods for studying retinal homeostasis and disease, including cell culture systems and animal models of disease, their generation, phenotypic and molecular characterization and use in therapeutic approaches.
Автор: Robert E. Anderson; Joe G. Hollyfield; Matthew M. Название: Retinal Degeneration ISBN: 1461362946 ISBN-13(EAN): 9781461362944 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: During the last few years, an explosion of infonnation has come from human genetics and molecular and cell biological studies as to the genetic basis for a number of fonns of inherited retinal degenerations.
Автор: Andreas Plaitakis Название: Cerebellar Degenerations: Clinical Neurobiology ISBN: 0792314905 ISBN-13(EAN): 9780792314905 Издательство: Springer Рейтинг: Цена: 59955.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book encompasses basic and clinical reports on the cerebellum and its primary atrophic disorders, the cerebellar degenerations. This field of clinical cerebellar sciences, no longer confined to the previously known descriptive level, is now advancing rapidly, propelled by rapid advances in neuroimaging, immunology, and molecular biology.
Автор: Seggane Musisi; Stanley Jacobson Название: Brain Degeneration and Dementia in Sub-Saharan Africa ISBN: 1493924559 ISBN-13(EAN): 9781493924554 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Stemming from a 2012 conference entitled Brain Degenerations and Emerging Mental Health Challenges in Sub-Saharan Africa, this book is aimed at both the general practitioner interested in CNS disorders, and the specialist who would like to know more about CNS pathology in Africa. By employing a broad defi nition of what brain degeneration means, the authors are able to touch upon everything from dementias and CNS malignancy to traumatic brain injury and CNS infective processes. This book draws from and builds upon the original conference presentations, and incorporates the most up-to-date science behind brain degeneration as well as actual case reports. Each of the book’s six sections off er the reader a deeper understanding of brain degeneration as it exists in Sub-Saharan Africa.
Описание: This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson’s disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are involved in specific functions as attractive therapeutic targets. It is expected to facilitate critical thought and discussion about the fundamental aspects of neurodegeneration in Parkinson’s disease and foster the development of therapeutic strategies among researchers and graduate students. Theories of idiopathic Parkinson’s etiology support roles for chronic inflammation and exposure to heavy metals or pesticides. Interestingly, as this project proposes, a case can be made that abnormalities in mitochondrial morphology and function are at the core of each of these theories. In fact, the most common approach to the generation of animal and cell-culture models of idiopathic Parkinson’s disease involves exposure to mitochondrial toxins. Even more compelling is the fact that most familial patients harbor genetic mutations that cause disruptions in normal mitochondrial morphology and function. While there remains to be no effective treatment for Parkinson’s disease, efforts to postpone, prevent and “cure” onset mitochondrial aberrations and neurodegeneration associated with Parkinson’s disease in various models are encouraging. While only about ten percent of Parkinson’s patients inherit disease-causing mutations, discovering common mechanisms by which familial forms of Parkinson’s disease manifest will likely shed light on the pathophysiology of the more common idiopathic form and provide insight to the general process of neurodegeneration, thus revealing therapeutic targets that will become more and more accessible as technology improves.
Название: Age-related macular degeneration ISBN: 3540064931 ISBN-13(EAN): 9783540064930 Издательство: Springer Рейтинг: Цена: 12990.00 р. Наличие на складе: Поставка под заказ.
Описание: Age-related macular degeneration (AMD) has become the most common cause of blindness. This work provides a review on the pathogenesis, epidemiology and risk factors, diagnostic methods and imaging modalities for age-related macular degeneration. Illustrated with both photographs and diagrams, it is useful for ophthalmologists.
Автор: Saunders Название: Degeneration and Regeneration in the Nervous System ISBN: 9058230228 ISBN-13(EAN): 9789058230225 Издательство: Taylor&Francis Рейтинг: Цена: 19906.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book brings authoritative, critical accounts of different aspects of the topic of "Degeneration and Regeneration in the Nervous System" to a wide audience, but particularly graduate students and their instructors, as well as those working in the field.
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