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Ionic Channels in Cells and Model Systems, Ram?n Latorre


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Автор: Ram?n Latorre
Название:  Ionic Channels in Cells and Model Systems
ISBN: 9781468450798
Издательство: Springer
Классификация:



ISBN-10: 1468450794
Обложка/Формат: Paperback
Страницы: 437
Вес: 0.62 кг.
Дата издания: 14.03.2013
Серия: Series of the Centro De Estudios Cient?ficos
Язык: English
Издание: Softcover reprint of
Иллюстрации: 37 illustrations, black and white; xxiii, 437 p. 37 illus.
Размер: 229 x 152 x 24
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book is based on a series of lectures for a course on ionic channels held in Santiago, Chile, on November 17-20, 1984. It is intended as a tutorial guide on the properties, function, modulation, and reconstitution of ionic channels, and it should be accessible to graduate students taking their first steps in this field. In the presentation there has been a deliberate emphasis on the spe­ cific methodologies used toward the understanding of the workings and function of channels. Thus, in the first section, we learn to read single­ channel records: how to interpret them in the theoretical frame of kinetic models, which information can be extracted from gating currents in re­ lation to the closing and opening processes, and how ion transport through an open channel can be explained in terms of fluctuating energy barriers. The importance of assessing unequivocally the origin and purity of mem­ brane preparations and the use of membrane vesicles and optical tech­ niques in the stUGY of ionic channels are also discussed in this section. The patch-clamp technique has made it possible to study ion channels in a variety of different cells and tissues not amenable to more conven­ tional electrophysiological methods. The second section, therefore, deals with the use of this technique in the characterization of ionic channels in different types of cells, ranging from plant protoplasts to photoreceptors.
Дополнительное описание: I. Methodologies.- 1 Kinetic Models and Channel Fluctuations.- 2 Single-Channel Currents and Postsynaptic Drug Actions.- 3 Voltage-Dependent Gating: Gating Current Measurement and Interpretation.- 4 Characterizing the Electrical Behavior of an Open Channe



Biological Membrane Ion Channels / Dynamics, Structure, and Applications

Автор: Chung S.H., Andersen O.S., Krishnamurthy V.
Название: Biological Membrane Ion Channels / Dynamics, Structure, and Applications
ISBN: 0387333231 ISBN-13(EAN): 9780387333236
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Deals with breakthroughs in ion-channel research that have been brought about by joint efforts of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these designed biomolecules. This book is aimed at researchers in nanodevices and biosensors, undergraduate and graduate students in biology.

Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

Автор: F.J. Alvarez-Leefmans; John M. Russell
Название: Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells
ISBN: 1475796870 ISBN-13(EAN): 9781475796872
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem- brane extremely rapidly.

Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

Автор: F.J. Alvarez-Leefmans; John M. Russell
Название: Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells
ISBN: 0306434261 ISBN-13(EAN): 9780306434266
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem- brane extremely rapidly.

Mechanosensitive Ion Channels

Автор: M.J. Lab; Andre Kamkin; I. Lozinsky; Irina Kiselev
Название: Mechanosensitive Ion Channels
ISBN: 9048176387 ISBN-13(EAN): 9789048176380
Издательство: Springer
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Цена: 34799.00 р.
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Описание: This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research.

Voltage-Gated Calcium Channels

Автор: Gerald Werner Zamponi
Название: Voltage-Gated Calcium Channels
ISBN: 1441934111 ISBN-13(EAN): 9781441934116
Издательство: Springer
Цена: 28732.00 р.
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Описание: oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar- macological targets in the treatment of a variety of disorders, such as epi- lepsy, hypertension, and pain. Voltage-gated calcium channels have there- fore been subject to intense study by numerous investigators over the past few decades, and an immense body of work has accumulated. In this book, we provide the first comprehensive overview of our current state of knowl- edge concerning this exciting field of research. Leading off with a general review of calcium signaling and techniques to measure calcium channel ac- tivity, the book delves into a provocative overview of the history of the cal- cium channel field, contributed by one of the key pioneers in the field. Dr. Richard Tsien. This is followed by an in depth review of the biochemical and molecular biological characterization of calcium channel genes by Drs. Catterall and Snutch whose research has resulted in major advances in the calcium channel field. A number of chapters are dedicated towards various aspects of calcium channel structure and function, including channel gat- ing, permeation, modulation and interactions with members of the exo- totic machinery--contributed by both established leaders and rising stars in the field.

Sensing with Ion Channels

Автор: Boris Martinac
Название: Sensing with Ion Channels
ISBN: 3662500671 ISBN-13(EAN): 9783662500675
Издательство: Springer
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Цена: 27950.00 р.
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Описание: All living cells are able to detect and translate environmental stimuli into biologically meaningful signals. Sensations of touch, hearing, sight, taste, smell or pain are essential to the survival of all living organisms. The importance of sensory input for the existence of life thus justifies the effort made to understand its molecular origins. Sensing with Ion Channels focuses on ion channels as key molecules enabling biological systems to sense and process the physical and chemical stimuli that act upon cells in their living environment. Its aim is to serve as a reference to ion channel specialists and as a source of new information to non specialists who want to learn about the structural and functional diversity of ion channels and their role in sensory physiology.

Ion Channels

Автор: T. Narahashi
Название: Ion Channels
ISBN: 0306452243 ISBN-13(EAN): 9780306452246
Издательство: Springer
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Цена: 34799.00 р.
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Описание: `Further establishes the reputation of the series...an invaluable resource.` -Trends in Pharmacological Sciences, from a review of Volume 3 Volume 4 explores such emergent topics as: three-dimensional conceptions of ion channel proteins based on the available structural and functional data;

Ion Channels

Автор: T. Narahashi
Название: Ion Channels
ISBN: 0306441667 ISBN-13(EAN): 9780306441660
Издательство: Springer
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Цена: 32004.00 р.
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Описание: In the past few years, the scientific community has witnessed significant progress in the study of ion channels. Gene cloning and monoclonal antibody techniques provide us with new approaches to the study of the molecular structure of ion channels.

Electrophysiology of Unconventional Channels and Pores

Автор: Anne H. Delcour
Название: Electrophysiology of Unconventional Channels and Pores
ISBN: 3319372351 ISBN-13(EAN): 9783319372358
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.

Voltage-Sensitive Ion Channels

Автор: H. Richard Leuchtag
Название: Voltage-Sensitive Ion Channels
ISBN: 9048173841 ISBN-13(EAN): 9789048173846
Издательство: Springer
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Цена: 32651.00 р.
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Описание: This book examines physically oriented approaches not covered in other ion-channel books, and it develops a new physics-based approach to the problem of molecular excitability.

Intracellular Regulation of Ion Channels

Автор: Martin Morad; Zalman Agus
Название: Intracellular Regulation of Ion Channels
ISBN: 3642846300 ISBN-13(EAN): 9783642846304
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Proceedings of the NATO Advanced Research Workshop on Intracellular Modulation of Cardiac and Neuronal Ion Channels at Il Ciocco, Lucca (Italy) from April 26-30, 1991


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