Bioinformatics of Genome Regulation and Structure, Nikolay Kolchanov; Ralf Hofestaedt
Автор: Sung Название: Algorithms in Bioinformatics ISBN: 1420070339 ISBN-13(EAN): 9781420070330 Издательство: Taylor&Francis Рейтинг: Цена: 13779.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presents an introduction to the algorithmic techniques applied in bioinformatics. For each topic, this title details the biological motivation, defines the corresponding computational problems, and includes examples to illustrate each algorithm.
Описание: This book takes the novel approach to cover both the sequence and structure analysis of proteins in one volume and from an algorithmic perspective. Key features of the book include:* Provides a comprehensive introduction to the analysis of protein sequence and structure analysis.
Описание: Contains papers based on the presentations at the 8th Annual International Workshop on Bioinformatics and Systems Biology held at the Teikyo Hotel, Berlin, from June 9 to June 10, 2008. This workshop started in 2001 as an event for doctoral students to present and discuss their research results and approaches in bioinformatics and systems biology.
Описание: Contains 18 peer-reviewed papers based on the presentations at the 10th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2010) held at Kyoto University from July 26 to July 28, 2010.
Автор: H.-W. Mewes; H. Seidel; B. Weiss Название: Bioinformatics and Genome Analysis ISBN: 3662047497 ISBN-13(EAN): 9783662047491 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Bioinformatics is emerging as a field with ever-increasing promise, ur- gency, and necessity. All three of these facets can be seen in the con- text of the recent sequencing of the human genome. The creation of a novel algorithm for the assembly of whole genome shotgun data sets accelerated the project and resulted in its near completion in 2001. The urgency became apparent with the landslide of data that ensued and the realization that current databases and tool sets are not up to the task. Finally, the necessity of bioinformatics as a facet of molecular biologi- cal research becomes evident in the impossibility of individual human comprehension of all the details of the functioning of a cell at the mo- lecular level, especially now that we stand on the edge of this preci- pice. We find ourselves at a time when we have the essentially complete genomes of human and mouse, and the completed sequences of Droso- phila melanogaster, Caenorhabditis elegans, several fungi including Saccharomyces cerevisiae, and many bacteria including Escherichia coli. There are volumes of mRNA expression data sets, high-density maps of highly variable SNPs for both human and mouse, physical marker maps for many other important agricultural and drug trial ani- mals, and a complete knock-out survey of yeast. In addition, the se- quencing of D. pseudoobscura and Caenorhabditis briggsae in the near future will provide unusual comparative genomic insights.
Автор: Nikolay Kolchanov; Ralf Hofestaedt; Luciano Milane Название: Bioinformatics of Genome Regulation and Structure II ISBN: 1461497701 ISBN-13(EAN): 9781461497707 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The last 15 years in development of biology were marked with accumulation of unprecedentedly huge arrays of experimental data. The information was amassed with exclusively high rates due to the advent of highly efficient experimental technologies that provided for high throughput genomic sequencing; of functional genomics technologies allowing investigation of expression dynamics of large groups of genes using expression DNA chips; of proteomics methods giving the possibility to analyze protein compositions of cells, tissues, and organs, assess the dynamics of the cell proteome, and reconstruct the networks of protein-protein interactions; and of metabolomics, in particular, high resolution mass spectrometry study of cell metabolites, and distribution of metabolic fluxes in the cells with a concurrent investigation of the dynamics of thousands metabolites in an individual cell. Analysis, comprehension, and use of the tremendous volumes of experimental data reflecting the intricate processes underlying the functioning of molecular genetic systems are unfeasible in principle without the systems approach and involvement of the state-of-the-art information and computer technologies and efficient mathematical methods for data analysis and simulation of biological systems and processes. The need in solving these problems initiated the birth of a new science— postgenomic bioinformatics or systems biology in silico.
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