Molecular Targeting and Signal Transduction, Rakesh Kumar
Автор: Groner Название: Targeted Interference with Signal Transduction Events ISBN: 3642068340 ISBN-13(EAN): 9783642068348 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book does nothing less than lay out the state of development of tomorrow`s cancer drugs, directed against growth factors, growth factor receptors and intracellular signaling molecules with kinase activities.
Описание: This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide.
Автор: Wen-Sheng Wu; Chi-Tan Hu Название: Signal Transduction in Cancer Metastasis ISBN: 9400733585 ISBN-13(EAN): 9789400733589 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. It highlights the initial stage of tumor metastasis.
Автор: David A. Frank Название: Signal Transduction in Cancer ISBN: 147577821X ISBN-13(EAN): 9781475778212 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells.
Автор: Andrew F. Wilks; Ailsa G. Harpur Название: Intracellular Signal Transduction: The JAK-STAT Pathway ISBN: 3662220520 ISBN-13(EAN): 9783662220528 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is the first one written about the JAK/STAT pathway. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself.
Описание: Since then, the interest in the mechanisms by which reactive oxygen and nitrogen species (ROS/RNS) can modulate the cell`s response has tremendously grown, paralleling the intense efforts towards identifying new signaling pathways in which phosphorylation/dephosphorylation events take center stage.
Автор: Kaufman Название: Molecular Targeting in Oncology ISBN: 1617376531 ISBN-13(EAN): 9781617376535 Издательство: Springer Рейтинг: Цена: 32651.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer.
Автор: Markus Schwaiger; Ludger Dinkelborg; Hermann Schwe Название: From Morphological Imaging to Molecular Targeting ISBN: 3662073129 ISBN-13(EAN): 9783662073124 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Because of the current progress in molecular medicine (genomics, proteomics), a plethora of new and often human-specific targets are being identified. These targets often play a significant role in the pathogenesis of diseases, and identifying them offers the potential for early diagnosis and intervention. An early in vivo validation of specific ligands binding to these targets in humans is needed to as- sess their potential for targeted imaging and radiotherapy. Further- VI Preface more, such validation studies may allow for a better understanding of the molecular processes underlying phannacologic activity and therefore for a more successful development of phannaceuticals in general. The purpose of the Ernst Schering Research Foundation (ESRF) Workshop 48 was to provide a forum for an open exchange on the state of the art in the early development of such radiophanna- ceuticals. Experts from academia, industry, and regulatory authori- ties were invited to give presentations on aspects covering the identi- fication of targets, preclinical studies on the safety of ligands, as well as their validation in human clinical trials. It was our intention to cover both the opportunities and the challenges that scientists in this field are facing. Radiopharmaceuticals are uniquely suitable for the above-men- tioned target validation studies.
Автор: Steven Kanner Название: Tumor Metabolome Targeting and Drug Development ISBN: 146149544X ISBN-13(EAN): 9781461495444 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism.
Описание: This book summarizes the roles, significance, and potential therapeutic targeting of transcriptional factors (TFs) from the perspective of signaling cascade. It details the physiologic and pathologic roles of TFs in specific representative organ systems.
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