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From Morphological Imaging to Molecular Targeting, Markus Schwaiger; Ludger Dinkelborg; Hermann Schwe


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Автор: Markus Schwaiger; Ludger Dinkelborg; Hermann Schwe
Название:  From Morphological Imaging to Molecular Targeting
ISBN: 9783662073124
Издательство: Springer
Классификация:



ISBN-10: 3662073129
Обложка/Формат: Paperback
Страницы: 196
Вес: 0.26 кг.
Дата издания: 16.01.2013
Серия: Ernst Schering Foundation Symposium Proceedings
Язык: English
Издание: Softcover reprint of
Иллюстрации: 5 tables, black and white; 7 illustrations, color; 12 illustrations, black and white; xiii, 196 p. 19 illus., 7 illus. in color.
Размер: 210 x 148 x 12
Читательская аудитория: Professional & vocational
Основная тема: Medicine & Public Health
Подзаголовок: Implications to Preclinical Development
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Because of the current progress in molecular medicine (genomics, proteomics), a plethora of new and often human-specific targets are being identified. These targets often play a significant role in the pathogenesis of diseases, and identifying them offers the potential for early diagnosis and intervention. An early in vivo validation of specific ligands binding to these targets in humans is needed to as- sess their potential for targeted imaging and radiotherapy. Further- VI Preface more, such validation studies may allow for a better understanding of the molecular processes underlying phannacologic activity and therefore for a more successful development of phannaceuticals in general. The purpose of the Ernst Schering Research Foundation (ESRF) Workshop 48 was to provide a forum for an open exchange on the state of the art in the early development of such radiophanna- ceuticals. Experts from academia, industry, and regulatory authori- ties were invited to give presentations on aspects covering the identi- fication of targets, preclinical studies on the safety of ligands, as well as their validation in human clinical trials. It was our intention to cover both the opportunities and the challenges that scientists in this field are facing. Radiopharmaceuticals are uniquely suitable for the above-men- tioned target validation studies.


Erythrocyte Engineering for Drug Delivery and Targeting

Автор: Magnani Mauro
Название: Erythrocyte Engineering for Drug Delivery and Targeting
ISBN: 0306476916 ISBN-13(EAN): 9780306476914
Издательство: Springer
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Цена: 22359.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Includes topics such as electrochemical nuclear magnetic resonance (EC-NMR), the advances in the use of ab initio quantum chemical calculations in electrochemistry, the macroscopic and statistical thermodynamic models developed to describe adsorption phenomena on electrodes, and electrochemical promotion. This volume contains research results on plant lipids,including their structure, analysis, biosynthesis, regulation, physiological function, environmental aspects, and biotechnology, obtained world-wide during 2000-2002.

Morphological Mouse Phenotyping

Автор: Ruberte, Jose
Название: Morphological Mouse Phenotyping
ISBN: 0128129727 ISBN-13(EAN): 9780128129722
Издательство: Elsevier Science
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Цена: 22254.00 р.
Наличие на складе: Поставка под заказ.

Описание:

Morphological Mouse Phenotyping: Anatomy, Histology and Imaging is an atlas of explanatory diagrams and text that guides the reader through normal mouse anatomy, histology, and imaging. The book is targeted for mouse researchers and veterinarian and human pathologists, and presents a complete, integrative description of normal mouse morphology.

Disease animal models are fundamental in research to improve human health. The success of using genetically engineered mice to evaluate molecular disease hypotheses has encouraged the development of massive global projects, making the mouse the most used animal disease model. Laboratory mouse populations are straining the housing capacity of pharmaceutical and biotechnology companies, as well as public research institutions. However, the scientific community lacks sufficient expertise in morphological phenotyping to effectively characterize and validate these animal models. The mouse displays fundamental morphological similarities to humans; however, a mouse is not a man.

  • Features more than 2,200 original images showing the anatomy, histology, and cellular structure of mouse organs
  • Includes images specifically produced for this book in the Mouse Imaging Platform (Center for Animal Biotechnology and Gene Therapy, Universitat Aut noma de Barcelona)
  • Offers an integrative vision of mouse morphology using correlative X-ray, computed tomography, magnetic resonance, and ultrasound images
  • Employs classical anatomical techniques such as conventional dissection, skeletal preparations, vascular injections, and histological, immunohistochemical, and electron microscopy techniques to characterize mouse morphology
The Mechanoreceptors of the Mammalian Skin Ultrastructure and Morphological Classification

Автор: Z. Halata
Название: The Mechanoreceptors of the Mammalian Skin Ultrastructure and Morphological Classification
ISBN: 3540070974 ISBN-13(EAN): 9783540070979
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Whilst most of the senses (hearing, sight, smell and taste) have their own organs, the tactile sense is dependent on the sensory nerve endings of the periph- eral processes of the nerve cells in the spinal ganglia. Some areas, such as the skin of the back, have relatively few nerve endings, whilst other parts (e.g.

Drug Delivery  Fundamentals and Applications, Second Edition

Автор: Anya M Hillery
Название: Drug Delivery Fundamentals and Applications, Second Edition
ISBN: 1482217716 ISBN-13(EAN): 9781482217711
Издательство: Taylor&Francis
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Цена: 18374.00 р.
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Описание:

This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches.

Features:

  • Offers a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug delivery and targeting
  • Presents an in-depth analysis of the opportunities and obstacles afforded by the application of nanotechnologies for drug delivery and targeting
  • Includes a revised and expanded section on the major epithelial routes of drug delivery currently under investigation
  • Describes the most recent, emerging, and innovative technologies of drug delivery
  • Provides real-life examples of the clinical translation of drug delivery technologies through the use of case studies
  • Discusses the pertinent regulatory hurdles and safety issues of drug delivery and targeting systems--crucial considerations in order to achieve licensing approval for these new technologies
Molecular Targeting in Oncology

Автор: Kaufman
Название: Molecular Targeting in Oncology
ISBN: 1617376531 ISBN-13(EAN): 9781617376535
Издательство: Springer
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Цена: 32651.00 р.
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Описание: This book presents an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer.

Molecular Targeting and Signal Transduction

Автор: Rakesh Kumar
Название: Molecular Targeting and Signal Transduction
ISBN: 1475779682 ISBN-13(EAN): 9781475779684
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation.


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