Biology and Pathology of Astrocyte-Neuron Interactions, Sergey Fedoroff; Bernhard H.J. Juurlink; J. Ronald
Автор: Wulfram Gerstner Название: Spiking Neuron Models ISBN: 0521890799 ISBN-13(EAN): 9780521890793 Издательство: Cambridge Academ Рейтинг: Цена: 10454.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aimed at courses in computational neuroscience, theoretical biology, biophysics, or neural networks, this 2002 text will suit students of physics, mathematics, or computer science, as well as biologists who are interested in mathematical modelling. A large number of worked examples are embedded in the profusely-illustrated text.
Автор: Hubbard, Jacqueline Название: Astrocytes and Epilepsy ISBN: 0128024011 ISBN-13(EAN): 9780128024010 Издательство: Elsevier Science Рейтинг: Цена: 14654.00 р. Наличие на складе: Поставка под заказ.
Описание:
Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory." Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy.
Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy.
Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume
Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions
Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation
Автор: Richard Milner Название: Astrocytes ISBN: 1493958593 ISBN-13(EAN): 9781493958597 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book is a comprehensive guide to techniques for astrocyte cell culture, and more specialized approaches for studying astrocyte functions, both in vitro and in vivo. Offers step-by-step protocols, troubleshooting tips and more.
Описание: This book details the latest aspects of the culture of neural cells and explains the practical and theoretical considerations of the techniques involved. It features step-by-step, readily reproducible laboratory protocols and expert implementation advice.
Автор: Sergey Fedoroff; Bernhard H.J. Juurlink; J. Ronald Название: Biology and Pathology of Astrocyte-Neuron Interactions ISBN: 0306445654 ISBN-13(EAN): 9780306445651 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Second Altschul Symposium held in Saskatoon, Saskatchewan, Canada, May 20-23, 1992.
Автор: Fried Itzhak, Rutishauser Ueli, Cerf Moran Название: Single Neuron Studies of the Human Brain: Probing Cognition ISBN: 0262027208 ISBN-13(EAN): 9780262027205 Издательство: MIT Press Рейтинг: Цена: 11004.00 р. Наличие на складе: Нет в наличии.
Описание:
Foundational studies of the activities of spiking neurons in the awake and behaving human brain and the insights they yield into cognitive and clinical phenomena.
In the last decade, the synergistic interaction of neurosurgeons, engineers, and neuroscientists, combined with new technologies, has enabled scientists to study the awake, behaving human brain directly. These developments allow cognitive processes to be characterized at unprecedented resolution: single neuron activity. Direct observation of the human brain has already led to major insights into such aspects of brain function as perception, language, sleep, learning, memory, action, imagery, volition, and consciousness. In this volume, experts document the successes, challenges, and opportunity in an emerging field.
The book presents methodological tutorials, with chapters on such topics as the surgical implantation of electrodes and data analysis techniques; describes novel insights into cognitive functions including memory, decision making, and visual imagery; and discusses insights into diseases such as epilepsy and movement disorders gained from examining single neuron activity. Finally, contributors consider future challenges, questions that are ripe for investigation, and exciting avenues for translational efforts.
Contributors Ralph Adolphs, William S. Anderson, Arjun K. Bansal, Eric J. Behnke, Moran Cerf, Jonathan O. Dostrovsky, Emad N. Eskandar, Tony A. Fields, Itzhak Fried, Hagar Gelbard-Sagiv, C. Rory Goodwin, Clement Hamani, Chris Heller, Mojgan Hodaie, Matthew Howard III, William D. Hutchison, Matias Ison, Hiroto Kawasaki, Christof Koch, Rudiger Kohling, Gabriel Kreiman, Michel Le Van Quyen, Frederick A. Lenz, Andres M. Lozano, Adam N. Mamelak, Clarissa Martinez-Rubio, Florian Mormann, Yuval Nir, George Ojemann, Shaun R. Patel, Sanjay Patra, Linda Philpott, Rodrigo Quian Quiroga, Ian Ross, Ueli Rutishauser, Andreas Schulze-Bonhage, Erin M. Schuman, Demetrio Sierra-Mercado, Richard J. Staba, Nanthia Suthana, William Sutherling, Travis S. Tierney, Giulio Tononi, Oana Tudusciuc, Charles L. Wilson
Автор: Levitan Irwin B., Kaczmarek Leonard K. Название: The Neuron: Cell and Molecular Biology ISBN: 0199773890 ISBN-13(EAN): 9780199773893 Издательство: Oxford Academ Рейтинг: Цена: 17424.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Fourth Edition of The Neuron features newly updated chapters and scores of full-color figures, making it an ideal first course in the cell and molecular biology of nerve cells.
Описание: This intriguing book was born out of the many discussions the authors had in the past 10 years about the role of scale-free structure and dynamics in producing intelligent behavior in brains. The microscopic dynamics of neural networks is well described by the prevailing paradigm based in a narrow interpretation of the neuron doctrine.
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