Clinical Applications of Monoclonal Antibodies, Ron Hubbard; Vincent Marks

Автор: Ritter
Название: Monoclonal Antibodies
ISBN: 0521425034 ISBN-13(EAN): 9780521425032
Издательство: Cambridge Academ
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Описание: Monoclonal antibodies have a very important and wide-ranging role in many areas of biomedical research and this volume is amongst the very first to combine technical and clinical aspects of the subject.

Автор: Albitar Maher
Название: Monoclonal antibodies / methods and protocols
ISBN: 1588295672 ISBN-13(EAN): 9781588295675
Издательство: Springer
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Описание: Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies.Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy.

Автор: Kresina
Название: Monoclonal Antibodies
ISBN: 0824781163 ISBN-13(EAN): 9780824781163
Издательство: Taylor&Francis
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Описание: Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of

Автор: Michael Steinitz (Editor)
Название: Human Monoclonal Antibodies: Methods and Protocols
ISBN: 1627035850 ISBN-13(EAN): 9781627035859
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.

Автор: Martin Rosenberg; R. Balint; Gordon P. Moore; C.F.
Название: The Pharmacology of Monoclonal Antibodies
ISBN: 3642784348 ISBN-13(EAN): 9783642784347
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents.

Автор: Michael Steinitz
Название: Human Monoclonal Antibodies
ISBN: 1493960199 ISBN-13(EAN): 9781493960194
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.

Автор: Shepherd
Название: Monoclonal Antibodies
ISBN: 0199637229 ISBN-13(EAN): 9780199637225
Издательство: Oxford Academ
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Цена: 13464.00 р.
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Описание: This text covers the preparation, testing, derivation and application of monoclonal antibodies. Modern immunological techniques incorporating tried and tested methodologies are described, as well as the standard somatic hybridization and recombinant techniques, including the use of phage libraries.

Автор: Maher Albitar
Название: Monoclonal Antibodies
ISBN: 1617376469 ISBN-13(EAN): 9781617376467
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins.

Автор: Lucienne Chatenoud
Название: Monoclonal Antibodies in Transplantation
ISBN: 3662221977 ISBN-13(EAN): 9783662221976
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection.

Автор: Vincent Ossipow; Nicolas Fischer
Название: Monoclonal Antibodies
ISBN: 1493963228 ISBN-13(EAN): 9781493963225
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Monoclonal Antibodies: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed modern approaches to isolate and characterize monoclonal antibodies against carefully selected epitopes. This edition includes new chapters covering the key steps to generate high quality monoclonals via different methods, from antigen generation to epitope mapping and quality control of the purified IgG. Chapters are divided into four parts corresponding to four distinct objectives. Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Monoclonal Antibodies: Methods and Protocols, Second Edition provides crucial initial steps of monoclonal antibody generation and characterization with state-of-the art protocols.

Автор: R. Gieseler; Johann H. Peters; G. K?hler; P. Debba
Название: Monoclonal Antibodies
ISBN: 3642745342 ISBN-13(EAN): 9783642745348
Издательство: Springer
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Цена: 18284.00 р.
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Описание: With contributions by numerous authors

Автор: Edgar Engleman
Название: Human Hybridomas and Monoclonal Antibodies
ISBN: 1468449516 ISBN-13(EAN): 9781468449518
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied.