Monoclonal Antibodies, Maher Albitar

Автор: Michael Steinitz (Editor)
Название: Human Monoclonal Antibodies: Methods and Protocols
ISBN: 1627035850 ISBN-13(EAN): 9781627035859
Издательство: Springer
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Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.

Автор: Vincent Ossipow; Nicolas Fischer
Название: Monoclonal Antibodies
ISBN: 1493963228 ISBN-13(EAN): 9781493963225
Издательство: Springer
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Описание: Monoclonal Antibodies: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed modern approaches to isolate and characterize monoclonal antibodies against carefully selected epitopes. This edition includes new chapters covering the key steps to generate high quality monoclonals via different methods, from antigen generation to epitope mapping and quality control of the purified IgG. Chapters are divided into four parts corresponding to four distinct objectives. Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Monoclonal Antibodies: Methods and Protocols, Second Edition provides crucial initial steps of monoclonal antibody generation and characterization with state-of-the art protocols.

Автор: Albitar Maher
Название: Monoclonal antibodies / methods and protocols
ISBN: 1588295672 ISBN-13(EAN): 9781588295675
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies.Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy.

Автор: Michael Steinitz
Название: Human Monoclonal Antibodies
ISBN: 1493960199 ISBN-13(EAN): 9781493960194
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.

Автор: Stewart Sell; Ralph Reisfeld
Название: Monoclonal Antibodies in Cancer
ISBN: 0896030687 ISBN-13(EAN): 9780896030688
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Monoclonal antibody technology from its earliest moments has offered revolutionary expectations for the diagnosis and treatment of cancer.

Автор: Marie-Luise Sautter-Bihl; Heiner Bihl; Michael Wan
Название: Systemic Radiotherapy with Monoclonal Antibodies
ISBN: 364279954X ISBN-13(EAN): 9783642799549
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Almost a century ago Paul Ehrlich introduced the "magic bullet" concept of targeting therapeutic agents to specific tissues in order to reduce systemic toxicity.

Автор: R. Ceriani
Название: Monoclonal Antibodies and Breast Cancer
ISBN: 0898387396 ISBN-13(EAN): 9780898387391
Издательство: Springer
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Цена: 33401.00 р.
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Описание: Proceedings of the International Workshop on Monoclonal Antibodies and Breast Cancer, held in San Francisco, California, November 8-9, 1984

Автор: James W. Larrick; C. Borrebaeck
Название: Therapeutic Monoclonal Antibodies
ISBN: 1349118966 ISBN-13(EAN): 9781349118960
Издательство: Springer
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Цена: 15672.00 р.
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Описание: A review of therapeutic antibodies which have commercial potential. It discusses PCR cloning of Igs, immortalization by gene transfer, scale up production, infectious diseases, viruses, bacteria, parisites, inflammation/immunology, blood grouping, cells, cytokines, tumours and MDR.

Автор: R. Ceriani
Название: Monoclonal Antibodies and Breast Cancer
ISBN: 1461296374 ISBN-13(EAN): 9781461296379
Издательство: Springer
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Цена: 13275.00 р.
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Описание: Proceedings of the International Workshop on Monoclonal Antibodies and Breast Cancer, held in San Francisco, California, November 8-9, 1984

Автор: Martin Rosenberg; R. Balint; Gordon P. Moore; C.F.
Название: The Pharmacology of Monoclonal Antibodies
ISBN: 3642784348 ISBN-13(EAN): 9783642784347
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents.

Автор: Ron Hubbard; Vincent Marks
Название: Clinical Applications of Monoclonal Antibodies
ISBN: 1461288614 ISBN-13(EAN): 9781461288619
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Immunology has come a long way in the hundred or so years since the general concepts were first enuciated by Metchnikoff, Ehrlich, Von Bebring and others, One of the landmarks in this progress was the invention and development of monoclonal antibody secreting hybridomas by Milstein and bis co-workers in Cambridge.

Автор: Lucienne Chatenoud
Название: Monoclonal Antibodies in Transplantation
ISBN: 3662221977 ISBN-13(EAN): 9783662221976
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection.