Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases.
Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer's disease, Parkinson's disease and ischemic brain stroke, are discussed.
Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs.
Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases
Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab
Описание: In a classical alphabetical format, this two-volume reference covers more than 1000 painstakingly screened natural product structures. For each compound or compound class, a basic chemical characterization is given, followed by a description of the biological source and a discussion of their pharmaceutical potential as lead molecules for new drugs.
Автор: Frank E. Koehn Название: Natural Products and Cancer Drug Discovery ISBN: 148999565X ISBN-13(EAN): 9781489995650 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With reliable commentary and analysis in a sector often associated with outlandish claims, this volume provides a valuable overview of how natural products could generate new cancer therapeutics as well as mitigating the deleterious effects of chemotherapy.
Автор: Brahmachari, Goutam Название: Discovery and Development of Antidiabetic Agents from Natural Pro ISBN: 0128094508 ISBN-13(EAN): 9780128094501 Издательство: Elsevier Science Рейтинг: Цена: 23244.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic.
Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications.
Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics.
Автор: Ute Roessner; Daniel Anthony Dias Название: Metabolomics Tools for Natural Product Discovery ISBN: 1493963015 ISBN-13(EAN): 9781493963010 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses. It features step-by-step, readily reproducible protocols.
Автор: Ute Roessner; Daniel Anthony Dias Название: Metabolomics Tools for Natural Product Discovery ISBN: 1627035761 ISBN-13(EAN): 9781627035767 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses. It features step-by-step, readily reproducible protocols.
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