Natural Products and Cancer Drug Discovery, Frank E. Koehn
Автор: Haiyong Han; Paul Grippo Название: Drug Discovery in Pancreatic Cancer ISBN: 1489982752 ISBN-13(EAN): 9781489982759 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There have been tremendous advances in cancer drug discovery, and in the area of molecular and genetic models and technologies. In this book, experts describe the latest developments in the application of these models and technologies in pancreatic cancer.
It's in Your DNA: From Discovery to Structure, Function and Role in Evolution, Cancer and Aging describes, in a clear, approachable manner, the progression of the experiments that eventually led to our current understanding of DNA. This fascinating work tells the whole story from the discovery of DNA and its structure, how it replicates, codes for proteins, and our current ability to analyze and manipulate it in genetic engineering to begin to understand the central role of DNA in evolution, cancer, and aging.
While telling the scientific story of DNA, this captivating treatise is further enhanced by brief sketches of the colorful lives and personalities of the key scientists and pioneers of DNA research. Major discoveries by Meischer, Darwin, and Mendel and their impacts are discussed, including the merging of the disciplines of genetics, evolutionary biology, and nucleic acid biochemistry, giving rise to molecular genetics.
After tracing development of the gene concept, critical experiments are described and a new biological paradigm, the hologenome concept of evolution, is introduced and described. The final two chapters of the work focus on DNA as it relates to cancer and gerontology.
This book provides readers with much-needed knowledge to help advance their understanding of the subject and stimulate further research. It will appeal to researchers, students, and others with diverse backgrounds within or beyond the life sciences, including those in biochemistry, genetics/molecular genetics, evolutionary biology, epidemiology, oncology, gerontology, cell biology, microbiology, and anyone interested in these mechanisms in life.
Highlights the importance of DNA research to science and medicine
Explains in a simple but scientifically correct manner the key experiments and concepts that led to the current knowledge of what DNA is, how it works, and the increasing impact it has on our lives
Emphasizes the observations and reasoning behind each novel idea and the critical experiments that were performed to test them
Автор: J. Mulzer; R. Bohlmann Название: The Role of Natural Products in Drug Discovery ISBN: 3662040441 ISBN-13(EAN): 9783662040447 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products.
Автор: Kuete Victor Название: Biodiversity, Natural Products and Cancer Treatment ISBN: 9814583502 ISBN-13(EAN): 9789814583503 Издательство: World Scientific Publishing Рейтинг: Цена: 20592.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book is the first of its kind in bringing together biodiversity, chemical ecology, phytochemistry and cancer therapy. The highlight of the book is an exhaustive compilation of scientific data on biodiversity of medicinal plants, biodiversity and metagenomics, chemical ecology of medicinal plants, chemical ecology of marine organisms, natural products from terrestrial microbial organisms with activity towards cancer cells, marine organisms, ethnopharmacology and phytotherapy, contribution of African flora in world fight against cancer, natural products derived from terrestrial plants with activity towards cancer cells and established anticancer drugs from natural origin.
The book discusses the state-of-the-art of each topic to serve as reference resource tools for graduate students as well as scientists and scholars in pharmaceutical sciences, pharmacology, organic chemistry and biochemistry, pharmacognosy, phytochemistry, ethnomedicine and ethnopharmacology, complementary and alternative medicine, medical and public health sciences and others. It includes cutting-edge developments in anticancer discovery from both medicinal plants and organisms.
Автор: John M. Pezzuto; Nanjoo Suh Название: Natural Products in Cancer Prevention and Therapy ISBN: 3642345743 ISBN-13(EAN): 9783642345746 Издательство: Springer Рейтинг: Цена: 43100.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Chemoprevention of Esophageal Squamous Cell Carcinoma with Berries, by Gary D. Stoner and Li-Shu Wang
Cancer Prevention by Different Forms of Tocopherols, by Chung S. Yang and Nanjoo Suh
Cancer Chemopreventive and Therapeutic Potential of Guggulsterone, by Inas Almazari and Young-Joon Surh
Inhibition of UVB-Induced Nonmelanoma Skin Cancer: A Path from Tea to Caffeine to Exercise to Decreased Tissue Fat, by Allan H. Conney, You-Rong Lou, Paul Nghiem, Jamie J. Bernard, George C. Wagner and Yao-Ping Lu
Cancer Chemoprevention and Nutri-Epigenetics: State of the Art and Future Challenges, by Clarissa Gerhauser
A Perspective on Dietary Phytochemicals and Cancer Chemoprevention: Oxidative Stress, Nrf2, and Epigenomics, by Zheng-Yuan Su, Limin Shu, Tin Oo Khor, Jong Hun Lee, Francisco Fuentes and Ah-Ng Tony Kong
Keap1-Nrf2 Signaling: A Target for Cancer Prevention by Sulforaphane, by Thomas W. Kensler, Patricia A. Egner, Abena S. Agyeman, Kala Visvanathan, John D. Groopman, Jian-Guo Chen, Tao-Yang Chen, Jed W. Fahey and Paul Talalay
Chemoprotection Against Cancer by Isothiocyanates: A Focus on the Animal Models and the Protective Mechanisms, by Albena T. Dinkova-Kostova
Human Cancer Chemoprevention: Hurdles and Challenges, by Vaqar Mustafa Adhami and Hasan Mukhtar
Personalizing Lung Cancer Prevention Through a Reverse Migration Strategy, by Kathryn A. Gold, Edward S. Kim, Ignacio I. Wistuba and Waun K. Hong
Natural-Agent Mechanisms and Early-Phase Clinical Development, by Janet L. Wang, Kathryn A. Gold and Scott M. Lippman
Автор: John M. Pezzuto; Nanjoo Suh Название: Natural Products in Cancer Prevention and Therapy ISBN: 3642427235 ISBN-13(EAN): 9783642427237 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Chemoprevention of Esophageal Squamous Cell Carcinoma with Berries, by Gary D. Stoner and Li-Shu Wang
Cancer Prevention by Different Forms of Tocopherols, by Chung S. Yang and Nanjoo Suh
Cancer Chemopreventive and Therapeutic Potential of Guggulsterone, by Inas Almazari and Young-Joon Surh
Inhibition of UVB-Induced Nonmelanoma Skin Cancer: A Path from Tea to Caffeine to Exercise to Decreased Tissue Fat, by Allan H. Conney, You-Rong Lou, Paul Nghiem, Jamie J. Bernard, George C. Wagner and Yao-Ping Lu
Cancer Chemoprevention and Nutri-Epigenetics: State of the Art and Future Challenges, by Clarissa Gerhauser
A Perspective on Dietary Phytochemicals and Cancer Chemoprevention: Oxidative Stress, Nrf2, and Epigenomics, by Zheng-Yuan Su, Limin Shu, Tin Oo Khor, Jong Hun Lee, Francisco Fuentes and Ah-Ng Tony Kong
Keap1-Nrf2 Signaling: A Target for Cancer Prevention by Sulforaphane, by Thomas W. Kensler, Patricia A. Egner, Abena S. Agyeman, Kala Visvanathan, John D. Groopman, Jian-Guo Chen, Tao-Yang Chen, Jed W. Fahey and Paul Talalay
Chemoprotection Against Cancer by Isothiocyanates: A Focus on the Animal Models and the Protective Mechanisms, by Albena T. Dinkova-Kostova
Human Cancer Chemoprevention: Hurdles and Challenges, by Vaqar Mustafa Adhami and Hasan Mukhtar
Personalizing Lung Cancer Prevention Through a Reverse Migration Strategy, by Kathryn A. Gold, Edward S. Kim, Ignacio I. Wistuba and Waun K. Hong
Natural-Agent Mechanisms and Early-Phase Clinical Development, by Janet L. Wang, Kathryn A. Gold and Scott M. Lippman
Автор: Asfar S Azmi Название: Systems Biology in Cancer Research and Drug Discovery ISBN: 9400794355 ISBN-13(EAN): 9789400794351 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A collation of chapters from the world`s leading experts in systems biology, this new publication traces its applications to cancer research and focuses on the use of the latest integrated and systems technologies in drug development and personalized medicine.
Автор: Ute Roessner; Daniel Anthony Dias Название: Metabolomics Tools for Natural Product Discovery ISBN: 1493963015 ISBN-13(EAN): 9781493963010 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses. It features step-by-step, readily reproducible protocols.
Автор: Ute Roessner; Daniel Anthony Dias Название: Metabolomics Tools for Natural Product Discovery ISBN: 1627035761 ISBN-13(EAN): 9781627035767 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses. It features step-by-step, readily reproducible protocols.
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