The Human T-Cell Receptor Repertoire and Transplantation, Peter van den Elsen

Автор: Marie-Paule Lefranc
Название: The T Cell Receptor FactsBook,
ISBN: 0124413528 ISBN-13(EAN): 9780124413528
Издательство: Elsevier Science
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Цена: 13551.00 р.
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Описание: This is a reference for all functional and ORF T-cell receptor genes. Introductory chapters provide up-to-date information on T-cell receptor structural and biological properties, chain synthesis, gene chromosomal localization, and organization of the TRA, TRB, TRG and TRD loci. This is followed by entries on all 168 functional and ORF variable, diversity, joining and constant genes, and a complete overview of the potential repertoire of the human T-cell receptor alpha, beta, gamma and delta loc

Автор: Gerard Pasterkamp
Название: Semaphorins: Receptor and Intracellular Signaling Mechanisms
ISBN: 1441924272 ISBN-13(EAN): 9781441924278
Издательство: Springer
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Цена: 32004.00 р.
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Описание: This book details our progress in understanding the receptor and intracellular signaling mechanisms utilized by semaphorins. The comprehensive overview of semaphorin biology and signaling presented in this book allows one to compare semaphorin functions between different biological systems.

Автор: Vivier Eric, Colonna Marco
Название: Immunobiology of Natural Killer Cell Receptors
ISBN: 3540260838 ISBN-13(EAN): 9783540260837
Издательство: Springer
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Цена: 26122.00 р.
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Описание: Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.

Автор: Rast
Название: Immune Receptors
ISBN: 1617791385 ISBN-13(EAN): 9781617791383
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Immunology has made significant progress in the past decade, driven forward by rapidly advancing technology and a renewed interest in the vast realm of innate immunity. The receptors that mediate these functions are at the front lines of both protective and regulative roles of the immune system.  In Immune Receptors: Methods and Protocols, expert researchers present a variety of experimental approaches to the characterization of immune receptors and the cell biology that mediates their functions.  These include imaging techniques that aim to understand receptor localization and trafficking, techniques to measure receptor-ligand interactions, strategies to identify novel ligands and methods to analyze downstream receptor signaling, as well as strategies for genomic and proteomic characterization of receptor repertoires. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immune Receptors: Methods and Protocols offers technical descriptions and protocols that will be useful both to investigators who are interested in carrying out these procedures and to those who seek a deeper understanding of the bench science that lies behind the immunology literature.

Автор: Tomohiro Kurosaki; J?rgen Wienands
Название: B Cell Receptor Signaling
ISBN: 3319261312 ISBN-13(EAN): 9783319261317
Издательство: Springer
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Цена: 18284.00 р.
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Описание: Altogether, the discoveriespresented provide a better understanding of B cell biology and help to explainsome B cell-mediated pathogenicities, like autoimmune phenomena or theformation of B cell tumors, while also paving the way for eventually combating thesediseases.

Автор: Arthur M. Silverstein
Название: Paul Ehrlich`s Receptor Immunology:,
ISBN: 0126437653 ISBN-13(EAN): 9780126437652
Издательство: Elsevier Science
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Цена: 15180.00 р.
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Описание: This book describes the background to Paul Ehrlich's immunological works and theories and delves into the substance of his experiments in great detail.exploring these early developments in immunology, the book lays the foundation for modern concepts, providing immunologists, biomedical researchers, and students the context for the discoveries in their field.

Автор: Bruce Beutler; Hermann Wagner
Название: Toll-Like Receptor Family Members and Their Ligands
ISBN: 3642639755 ISBN-13(EAN): 9783642639753
Издательство: Springer
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Цена: 16979.00 р.
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Описание: On occasion, the innate immune system is referred to as the "primitive" immune system. On the contrary, the innate immune system has had time to achieve a level of refinement that is nothing short of dazzling, and a modicum of respect is at long last due.

Автор: Majed M. Hamawy
Название: IgE Receptor (Fc?RI) Function in Mast Cells and Basophils
ISBN: 3662220245 ISBN-13(EAN): 9783662220245
Издательство: Springer
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Цена: 16979.00 р.
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Описание: The high affinity IgE receptor (FceRI) plays a central role in allergic diseases including asthma, allergic rhinitis, atopic dermatitis, food and drug allergy. In addition, clinicians who are concerned with broadening their knowledge of the FceRI role in allergic diseases will find this book useful.

Автор: Eric Vivier; Marco Colonna
Название: Immunobiology of Natural Killer Cell Receptors
ISBN: 3642065457 ISBN-13(EAN): 9783642065453
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor.

Автор: Tak W. Mak
Название: The T-Cell Receptors
ISBN: 1468454080 ISBN-13(EAN): 9781468454086
Издательство: Springer
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Цена: 15672.00 р.
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Описание: The importance of thymus-dependent cells, or T cells, in the generation of a successful immune response was first realized in the early sixties.

Автор: Tammy Kielian
Название: Toll-like Receptors: Roles in Infection and Neuropathology
ISBN: 3642269117 ISBN-13(EAN): 9783642269110
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This book highlights traditional roles for TLRs in infectious diseases of the CNS. It also discusses recently emerging roles for TLRs in non-infectious neurodegenerative diseases and the challenges faced in these models with identifying endogenous ligands.