The Molecular Biology of Insect Disease Vectors, J.M. Crampton; C.B. Beard; C. Louis

Автор: Heinz Mehlhorn
Название: Arthropods as Vectors of Emerging Diseases
ISBN: 3642428533 ISBN-13(EAN): 9783642428531
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Описание: Global warming and globalization are the buzzwords of our time. They have nearly reached a religious status and those who deny their existence are considered modern heretics. Nevertheless, the earth has become an overcrowded village, traversable within a single day. Thus it is hardly surprising that besides persons and goods also agents of disease are easily transported daily from one end of the world to the other, threatening the health and lives of billions of humans and their animals. Agents of diseases (prions, viruses, bacteria, fungi and parasites) are not only transmitted by body contact or direct exchange of bodily fluids, but also by means of vectors which belong to the groups of licking or blood-sucking arthropods (mites, ticks, insects) that live close to humans and their houses. Without a doubt the recently accelerating globalization supports the import of agents of disease into countries where they never had been or where they had long since been eradicated, leading to a false sense of living on a “safe island.” These newly imported or reintroduced diseases – called “emerging diseases” – may lead to severe outbreaks in cases where the countries are not prepared to combat them, or in cases where viruses are introduced that cannot be controlled by medications or vaccines. Arthropods are well known vectors for the spread of diseases. Thus their invasion from foreign countries and their spreading close to human dwellings must be blocked everywhere (in donor and receptor countries) using safe and effective measures. This book presents reviews on examples of such arthropod-borne emerging diseases that lurk on the fringes of our crowded megacities. The following topics show that there is an ongoing invasion of potential vectors and that control measures must be used now in order to avoid disastrous outbreaks of mass diseases.

Автор: G. Dickson
Название: Molecular and Cell Biology of Human Gene Therapeutics
ISBN: 940104242X ISBN-13(EAN): 9789401042420
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Описание: advanced metastatic disease of solid tumors, dictates that each tumor mass, indeed each individual metastasis, will have a unique antigen and cytokine environment and hence unique response to immune modu- lation. Most chemotherapeutic regimes require a complete response or a good partial response for cure or good palliation.

Автор: H.R. Petty
Название: Molecular Biology of Membranes
ISBN: 1489911480 ISBN-13(EAN): 9781489911483
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Описание: This text attempts to introduce the molecular biology of cell membranes to students and professionals of diverse backgrounds. Although several membrane biology books are available, they do not integrate recent knowledge gained using modern molecular tools with more traditional membrane topics.

Автор: D. Wettstein
Название: Plant Molecular Biology
ISBN: 1461576008 ISBN-13(EAN): 9781461576006
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Описание: The present volume contains the invited lectures and abstracts of the posters presented at the NATO Advanced Study Institute on Plant Molecular Biology held at the Carlsberg Laboratory in Copenhagen, June 10 to 19. The Directors of the Advanced Study Institute would like to express their most sincere gratitude for financial support to the following: NATO Danish Natural Science Research Council Danish Agricultural and Veterinary Science Research Council Carlsbergs Mindelegat for Brygger J. C. Jacobsen Carlsberg and Tuborg Breweries International Society for Plant Molecular Biology Bayer AG, Leverkusen Hoechst AG, Frankfurt-Main Biotechnology, Ciba-Geigy, Research Triangle Park, North Carolina Cal gene, Davis, California Danisco Biotechnology, Copenhagen E. I. DuPont de Nemours & Co., Wilmington, Delaware Plant Science Foundation Holmegaards Glasvrerker, Fensmark Imperial Chemical Industries, Bracknell Martinus Nijhoff Publishers, Dordrecht Monsanto & Co., St. Louis, Missouri Novo, Copenhagen Rhone-Poulenc Agrochimie, Lyon Schering AG, Berlin Shell Research Ltd., London Unilever PLC, London Zoe con Research Institute, Sandoz, Palo Alto, California Without this generous support it would not have been possible to bring together so many outstanding plant molecular biologists for exchange of experience and knowledge and for animated as well as fruitful discussions on future experiments which can advance the understanding of plant biology. Also discussed were the possibilities to apply this knowledge to crop improvement. Diter von Wettstein Nam-Hai Chua v CONTENTS RIBULOSE-BISPHOSPHATE CARBOXYLASE Three-dimensional structure of ribulose-l,5-bisphosphate carboxylase/ oxygenase from Rhodospir111um rubrum ------. -------------------------- G. Schneider, Y. Lindqvist, C. -I. Branden and G.

Автор: Henry Weiner; Roger S. Holmes; Bendicht Wermuth
Название: Enzymology and Molecular Biology of Carbonyl Metabolism 5
ISBN: 1461358086 ISBN-13(EAN): 9781461358084
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Описание: Since the inception of these meetings in 1982, they have always been a satellite of the International Society for Biomedical Research on Alcoholism meeting. At our 1992 meeting in Dublin we learned that the next ISBRA meeting would be held in Brisbane, of all our previous meetings, I was very concerned Australia.

Автор: Dino Moras
Название: Crystallography in Molecular Biology
ISBN: 1468452746 ISBN-13(EAN): 9781468452747
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Описание: "Crystallography in Molecular Biology," a NATO Advanced Study Institute, was held on September 12-21, 1985, at the Bi schenberg near Strasbourg, France. The meeting, co-sponsored by EMBO and CNRS (Centre National de 1 a Recherche Scientifique), was attended by partici pants from 18 countries. The aim of the course was to gi ve an overvi ew of crystallography related to molecular biology with special emphasis on recent results and new methodo 1 ogi ca 1 approaches. Thi s fi e 1 d of research is expandi ng enormously, partly due to its primordial contribution to biotechnology. Protei n engi neeri ng, s i te-di rected mutagenesi s, drug and vacci n desi gn are some of the direct beneficiaries of crystallographic investigations. The need for large quantities of structural informations and the necessity to tackle more and more complex problems are a strong incenti- ve to develop new methods in order to overcome the varfous bottlenecks of a structure determi nati on. Impressi ve progresses have been made in the field of data collection, phase determination and refinement tech- ni cs. Despite some recent achi evements crystal growth is the 1 ast se- ri ous handi cap of the method. The course was a good opportunity for oarticipants to be up-to-date with many facets of single crystal crys- tallography.

Автор: F. Owen; R. Itzhaki
Название: Molecular and Cell Biology of Neuropsychiatric Diseases
ISBN: 9401043051 ISBN-13(EAN): 9789401043052
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Описание: is''0l m 5-HT Ante-mortem (m = metabolite) . ." Post-mortem m 0 Noradrenaline, -'-'-'-'0-J, -'-'-'-'-'-'- m Dopamine . '-'-'-'-'- . " Somatostatin . '1 Plaques Tangles * . ." . ." . 'I Synapse loss * ChAT " ACh synthesis l"-, . '-'-'-'-'-'-'-'-'-'-'-'-'-, -'-'-'-'-'-'-'-'-'-'-'-'-'-'- * Neuronal loss, -, - . ." * o 0. 1 0. 2 0. 3 0. 4 0. 5 0. 6 0. 7 0. 8 0. 9 1. 0 Correlation coefficient with dementia rating Figure 2. 1 Various neurotransmitter and neuropathological measures on neocortex obtained either at diagnostic craniotomy (ante-mortem) or post-mortem and re- lationship to cognitive impairment (dementia rating). Asterisks identify significant correlations. Negative and positive correlations are not identified in this represen- tation of the data. Only the physiologically relevant measure of cholinergic neurones (acetylcholine synthesis) and indices of cortical pyramidal neurone degeneration (neuronal loss, synapse loss and tangles) correlate with severity of dementia. Note the lack of correlation with the structural marker of cholinergic neurones, ChAT activity. Loss of enzyme exceeded that of acetylcholine synthesis (Sims et al., 1983a), suggesting a compensatory increase in synthesis in the few remaining neurones. Data derived from Palmer (1987) and Terry et al. (1991). emission tomography (PET) and magnetic resonance, may some day pro- vide routine insight into differences in brain functioning. Success in developing rapid and reliable diagnostic procedures, perhaps based on changes in body fluid that reflect specific alterations in brain protein metabolism, should ultimately play an important role in the clinical development of new therapeutic agents.

Автор: Tai Te Wu
Название: Analytical Molecular Biology
ISBN: 1475774818 ISBN-13(EAN): 9781475774818
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Описание: Analytical Molecular Biology illustrates the importance of simple analytical methods applied to some basic molecular biology problems, with an emphasis on the importance of biological problems, rather than the complexity of mathematics.

Автор: R.G. Herrmann; Brian A. Larkins
Название: Plant Molecular Biology 2
ISBN: 146136454X ISBN-13(EAN): 9781461364542
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Описание: Proceedings of a NATO ASI held in Elmau, Bavaria, Germany, May 14-23, 1990