Pharmacology of Hormonal Polypeptides and Proteins, Nathan Back
Автор: Alexander V. Yakubovich Название: Theory of Phase Transitions in Polypeptides and Proteins ISBN: 3642269532 ISBN-13(EAN): 9783642269530 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This thesis provides novel insights into protein folding by considering the problem from the point of view of statistical mechanics. It presents the first physically motivated quantitative description of the protein folding/unfolding transition.
Автор: Koreaki Ito Название: Regulatory Nascent Polypeptides ISBN: 4431550518 ISBN-13(EAN): 9784431550518 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights a new paradigm of translation control by regulatory nascent polypeptides, which is integrated into cellular regulatory systems. Translation lies in the hub of the central dogma of biology, in which the genetic information in the forms of 4-letter sentences is translated into 20-letter sentences: sequences of amino acids that constitute proteins, the functional molecules of life. The process involves a huge number of chemical reactions as well as physical movements of the ribosome along a messenger RNA and takes, on average, tens of seconds in prokaryotes and a few minutes in eukaryotes. Detailed knowledge about the progression of translation, called "elongation", only recently started to accumulate. Newly synthesized and growing polypeptides, called nascent polypeptides, can interact with the intra-ribosomal conduit, called the ribosomal exit tunnel, when they have some specific amino acid sequences, called "an arrest sequence". Such interaction leads to a halt in the elongation reaction. Resulting stalling of the ribosome on messenger RNA can affect the secondary structure and/or localization of the message in the cell, consequently leading to biological outputs such as elevation or reduction of a gene product. This book provides a first collection of knowledge focused on regulatory nascent polypeptides, which have been studied recently using diverse organisms including bacteria, plants, and animals. Readers will be impressed by a new paradigm showing that proteins can function even during the course of their biosynthesis and that the ribosome, the "factory" of protein production, interacts with and inspects its products to adjust the speed of completion of each product. Moreover, regulatory nascent polypeptides can sense or monitor physiological states of the cell and modulate its ability to arrest translation. Living organisms use such intricate control mechanisms of translational speed to regulate gene expression. This book will be a useful addition for established scientists while inspiring students and young scientists to gain deeper insights into the processes of expression of genetic information.
Автор: Kenneth W. McKerns; Vladimir Panti? Название: Hormonally Active Brain Peptides ISBN: 146159250X ISBN-13(EAN): 9781461592501 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: P. Katsoyannis Название: The Chemistry of Polypeptides ISBN: 1461345731 ISBN-13(EAN): 9781461345732 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leonidas Zervas, Emeritus Professor of organic chemistry at the University of Athens, and past president of the National Academy of Greece, cele- brated his seventieth birthday this past year.
Автор: J. Chayen Название: The Cytochemical Bioassay of Polypeptide Hormones ISBN: 3642814611 ISBN-13(EAN): 9783642814617 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The cytochemical bioassay system was described in a short abstract in 1971, and more fully, in the cytochemical bioassay of corticotrophin, in 1972.
Автор: T.K. Scott; M.L. Evans; W.P. Jacobs; H. Kaldewey; Название: Hormonal Regulation of Development II ISBN: 3642677339 ISBN-13(EAN): 9783642677335 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is the second of the set of three volumes in the Encyclopedia of Plant Physiology, New Series, that will cover the area of the hormonal regulation of plant growth and development.
Автор: Jonathan J. Li; Sara A. Li; Jan-Ake Gustafsson; Sa Название: Hormonal Carcinogenesis II ISBN: 1461275067 ISBN-13(EAN): 9781461275060 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For those of us who have labored in the field of hormonal carcinogenesis, it has been most gratifying to see its rapid growth and increasing relevance in recent years. Although many factors and forces have contributed to this phenomenon, a few appear particularly significant. Perhaps foremost is the realization that two of the most prevalent cancers which afflict women and men; that is, breast and prostate, have essential hormonal component(s) to their etiologies. This should not surprise us since the high frequency of these cancers in human populations has to date not been attributed to any exogenous physical, environmental, or dietary factor(s). A similar argument may be applied to other less prevalent but equally important cancers including ovarian, endometrial, testicular, cervico- vaginal, pituitary, thyroid, and sex hormone-associated hepatic neoplasms. The Office of Research on Women's Health and many women's interest groups have been instrumental in fostering research and public awareness on women's cancers. Similar concern is beginning to emerge for solely male cancers by other groups. To illustrate an example of the potential pervasive role of hormones in the human, particularly sex hormones, Figure I depicts the endogenous and known exogenous exposures to estrogens and progestins during a woman's lifetime, which may contribute to increased risk for hormonally-associated cancers . . = iii M. A. P. _ GI en 2 PoOlmenopauoal EstrogDn Proge. tln GI en J\ Ovulatory _ 2 Cyel. iii W DES EIP Menotr". 1 Ol, order.
Автор: Richard P. Pharis; David M. Reid Название: Hormonal Regulation of Development III ISBN: 3642677363 ISBN-13(EAN): 9783642677366 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: J. MacMillan; J.R. Bearder Название: Hormonal Regulation of Development I ISBN: 3642677061 ISBN-13(EAN): 9783642677069 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: G. Fischer; R. J. Wieser Название: Hormonally Defined Media ISBN: 3642692923 ISBN-13(EAN): 9783642692925 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Until some years ago serum or crude tissue extracts were used pre- dominantly or exclusively as media supplements for the cultivation of cells.
This thesis offers readers a comprehensive introduction to amyloid proteins and the computational methods used with them. Katrine Skeby critically assesses and compares both the literature and the experiments performed by other researchers, which further elevates the quality and relevance of her own work. Amyloid proteins are highly complex, and this research provides unparalleled insights, especially with regard to the origin of cytotoxicity and to developing technologies for early detection, revealing in detail the molecular mechanisms behind hIAPP behavior. Several studies within the thesis answer difficult questions which promote future research into the properties of amyloid proteins.
Автор: M. Kh. Chailakhyan; Vanya Loroch; Kenneth V. Thima Название: Sexuality in Plants and Its Hormonal Regulation ISBN: 146129133X ISBN-13(EAN): 9781461291336 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Here is the first book to treat the control of sexuality in plants. They include a review of the evolution and genetics of sexuality, including new data on the effect of primary environmental factors on sex expression and the influence of phytohormones on the expression of sexuality as a function of age.
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