Epigenetics and Psychiatric Disease, Grayson, Dennis

Автор: Johannes Backs, Timothy McKinsey
Название: Epigenetics in Cardiac Disease
ISBN: 3319414550 ISBN-13(EAN): 9783319414553
Издательство: Springer
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Цена: 14673.00 р. 20962.00 -30%
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Описание: This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.

Автор: Trygve Tollefsbol
Название: Epigenetics in Human Disease,
ISBN: 0123884152 ISBN-13(EAN): 9780123884152
Издательство: Elsevier Science
Цена: 16506.00 р.
Наличие на складе: Поставка под заказ.

Описание:

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike.
Comprehensive coverage of fundamental and emergent science and clinical usageSide-by-side coverage of the basis of epigenetic diseases and their treatmentsEvaluation of recent epigenetic clinical breakthroughs

Автор: Minarovits
Название: Patho-Epigenetics of Disease
ISBN: 1489991786 ISBN-13(EAN): 9781489991782
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This book describes the complex interplay of epigenetic regulatory mechanisms, and shows how these carefully orchestrated processes can go wrong, resulting in epigenetic reprogramming of the cells that may manifest in pathological changes.

Автор: Rousseaux
Название: Epigenetics and Human Reproduction
ISBN: 3642147720 ISBN-13(EAN): 9783642147722
Издательство: Springer
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Цена: 28734.00 р.
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Описание: Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Автор: L. Joseph Su; Tung-chin Chiang
Название: Environmental Epigenetics
ISBN: 1447166779 ISBN-13(EAN): 9781447166771
Издательство: Springer
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Цена: 23757.00 р.
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Описание: What is Epigenetics.- Epidemiology of environment and health.- Technologies in measuring epigenetics.- Epigenetic changes in hormone related disease.- Epigenetic effects of environmental chemicals bisphenol a and phthalates.- Environmental epigenetics: a role in endocrine diseases?.- Pregnancy exposures determine risk of breast cancer in multiple generations of offspring.- Environmental epigenetics and obesity - evidences from animal to epidemiologic studies.- Environmental toxicants, epigenetics and cancer.- Aging, genes, environment and epigenetics.- Epigenetics: The link between nature and nurture.- Gene-Environment Interactions in Human Health.- Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.- Conclusions: Lessons from epigenetic research: the impact of environmental stress can be accumulated and resulted in diverse outcome.

Автор: Trygve Tollefsbol
Название: Medical Epigenetics
ISBN: 0128032391 ISBN-13(EAN): 9780128032398
Издательство: Elsevier Science
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Цена: 22696.00 р.
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Описание: "

Medical Epigenetics" is an inclusive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic disease that affect these systems, and modes of treating epigenetic-based disorders and diseases. This book provides stand-alone coverage of all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics.

The expansion of the field of epigenetics has brought a wealth of information with respect to variations in phenotypes that are heritable. In addition, many advances have emerged that have shown epigenetic aberrations as central to a number of diseases and disorders that were previously thought to be manifested primarily through genetic factors. Along with the remarkable studies that have been made in our understanding of epigenetic-based diseases and disorders has come new information that allows treatments that target these many epigenetic aberrations. "Medical Epigenetics" brings all of this knowledge together to comprehensively review the state of medical epigenetics in one defining volume.

The basic design of "Medical Epigenetics" is to lead the reader from the fundamental mechanisms of epigenetics as they apply to humans through approaches for treating epigenetic-based diseases. This book begins with the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics. "Medical Epigenetics" closes with a chapter on future prospects in medical epigenetics. This book is by far the most complete book in the area of applied epigenetics.
Focuses on practical and applied aspects of medical epigeneticsIncludes peer-reviewed chapters with up-to-date coverage of emerging topics in medical epigenetics by leading expertsAppeals to those interested in fundamental epigenetics and inheritance, as well as those with more clinical interests including practicing physicians and other health care professionalsCovers the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics

Автор: Manel Esteller
Название: DNA Methylation, Epigenetics and Metastasis
ISBN: 9048169178 ISBN-13(EAN): 9789048169177
Издательство: Springer
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Цена: 34799.00 р.
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Автор: Janos Minarovits; Hans Helmut Niller
Название: Patho-Epigenetics of Infectious Disease
ISBN: 3319247360 ISBN-13(EAN): 9783319247366
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization. The present volume undertakes to highlight the interactions of infectious pathogens and their effector molecules with the epigenetic regulatory machinery of the cell. Clearly, the recent take-off of epigenetics research did not leave Research on Infectious Diseases and Infection-Associated Cancer untouched. This resulted in a great many of clinically relevant data on understanding the molecular mechanisms of chronic infectious disease. Infectious pathogen- and disease-specific epigenetic alterations are already being used for the early detection of malignant disease and for the prediction of chemotherapy resistance or response to treatment.

Автор: Trygve O. Tollefsbol
Название: Epigenetics of Aging
ISBN: 1489983104 ISBN-13(EAN): 9781489983107
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This seminal work covers the impact of epigenetics on aging, the epigenetics of age-related diseases, and future directions and perspectives on the epigenetics of aging. It covers the most recent advances that impact the longevity of living organisms.

Автор: Paolo Sassone Corsi; Yves Christen
Название: Epigenetics, Brain and Behavior
ISBN: 3642441084 ISBN-13(EAN): 9783642441080
Издательство: Springer
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Цена: 22201.00 р.
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Описание: Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. The focus of this volume is on critical epigenetic regulation and chromatin remodeling events that occur in the nervous system and on the presumed mechanisms that operate within neurons to translate them into long-lasting neuronal responses.

Автор: Paul Haggarty; Kristina Harrison
Название: Population Epigenetics
ISBN: 1493969013 ISBN-13(EAN): 9781493969012
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This detailed volume focuses on population epigenetics, which is of increasing interest to policy makers searching for explanations for complex epidemiological observations and conceptual models on which to base interventions.

Автор: Laurence, Jeffrey
Название: Translating Epigenetics to the Clinic
ISBN: 0128008024 ISBN-13(EAN): 9780128008027
Издательство: Elsevier Science
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Цена: 11706.00 р.
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Описание: Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the ‘diseases of modernity’—including pharmacological addiction, dementia, and ageing. . Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. The book promotes cross-disciplinary communication between the sub-specialties of medicine. In common with the rest of the books in Translational Medicine, the book remains unified in theme by emphasizing recent innovations, critical barriers to progress, and the new tools being used to overcome them. Also includes specific areas of research that require additional study to advance the field as a whole.