Cadillac Gage V-100 Commando 1960–71, Richard Lathrop, John McDonald
Автор: Gage, Nicole Название: Fundamentals of Cognitive Neuroscience ISBN: 0128038136 ISBN-13(EAN): 9780128038130 Издательство: Elsevier Science Рейтинг: Цена: 9094.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Fundamentals of Cognitive Neuroscience: A Beginner's Guide, Second Edition, is a comprehensive, yet accessible, beginner’s guide on cognitive neuroscience. This text takes a distinctive, commonsense approach to help newcomers easily learn the basics of how the brain functions when we learn, act, feel, speak and socialize. This updated edition includes contents and features that are both academically rigorous and engaging, including a step-by-step introduction to the visible brain, colorful brain illustrations, and new chapters on emerging topics in cognition research, including emotion, sleep and disorders of consciousness, and discussions of novel findings that highlight cognitive neuroscience’s practical applications. Written by two leading experts in the field and thoroughly updated, this book remains an indispensable introduction to the study of cognition.
Автор: Gage Название: Retrotransposition, Diversity and the Brain ISBN: 3642094376 ISBN-13(EAN): 9783642094378 Издательство: Springer Рейтинг: Цена: 17468.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Fondation IPSEN Colloque Medecine et Recherche was devoted to the interface between the complexity of brain organization and function, the mechanisms for generating diversity and genetic mobility.
Автор: Fred H. Gage Название: Gene Transfer and Therapy in the Nervous System ISBN: 3642848443 ISBN-13(EAN): 9783642848445 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Jos? Mar?a Frade; Fred H. Gage Название: Genomic Mosaicism in Neurons and Other Cell Types ISBN: 1493972790 ISBN-13(EAN): 9781493972791 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Neuromethods Series Preface... Preface... Table of Contents... Contributing Authors...
Part I Introduction
1. Principles and Approaches for Discovery and Validation of Somatic Mosaicism in the Human Brain Alexej Abyzov, Alexander E. Urban, and Flora M. Vaccarino
Part II Aneuploidy and Ploidy Variation
2. FISH-Based Assays for Detecting Genomic (Chromosomal) Mosaicism in Human Brain Cells Yuri B. Yurov, Svetlana G. Vorsanova, Ilia V. Soloviev, Alexei M. Ratnikov, and Ivan Y. Iourov
3. Flow Cytometric and Sorting Analyses for Nuclear DNA Content, Nucleotide Sequencing and Interphase FISH Gwendolyn E. Kaeser and Jerold Chun
4. Flow Cytometric Quantification, Isolation, and Subsequent Epigenetic Analysis of Tetraploid Neurons Noelia Lуpez-Sбnchez, Iris Patiсo-Parrado, and Josй M. Frade
5. A Cytomic Approach towards Genomic Individuality of Neurons Thomas Arendt, Birgit Belter, Martina K. Brьckner, Uwe Ueberham, Markus Morawski, and Attila Tarnok
Part III DNA Copy Number Variation
6. Single Cell CNV Detection in Human Neuronal Nuclei Margaret B. Wierman, Ian E. Burbulis, William D. Chronister, Stefan Bekiranov, and Michael J. McConnell
7. Multiple Annealing and Looping-Based Amplification Cycles (MALBAC) for the Analysis of DNA Copy Number Variation Chenghang Zong
8. Competitive PCR for Copy Number Assessment by Restricting dNTPs Luming Zhou, Robert A. Palais, Yotam Ardon, and Carl T. Wittwer
9. Using Cloning to Amplify Neuronal Genomes for Whole Genome Sequencing and Comprehensive Mutation Detection and Validation Jennifer L. Hazen, Michael A. Duran, Ryan P. Smith, Alberto R, Rodriguez, Greg S. Martin, Sergey Kupriyanov, Ira M. Hall, and Kristin K. Baldwin
Part IV LINE-1 Retrotransposition
10. Analysis of LINE-1 Retrotransposition in Neural Progenitor Cells and Neurons Angela Macia and Alysson R. Muotri
11. Estimation of LINE-1 Copy Number in the Brain Tissue and Isolated Neuronal Nuclei Miki Bundo, Tadafumi Kato, and Kazuya Iwamoto
12. Analysis of Somatic LINE-1 Insertions in Neurons Francisco J. Sanchez-Luque, Sandra R. Richardson, and Geoffrey J. Faulkner
13. Single-Cell Whole Genome Amplification and Sequencing to Study Neuronal Mosaicism and Diversity Patrick J. Reed, Meiyan Wang, Jennifer A. Erwin, Apuг C.M. Paquola, and Fred H. Gage
Part V Genetic and Genomic Mosaicism in Aging and Disease
14. FISH Analysis of Aging-Associated Aneuploidy in Neurons and Non-Neuronal Brain Cells Grasiella A. Andriani and Cristina Montagna
15. Genomic Analysis and In Vivo Functional Validation of Brain Somatic Mutations Leading to Focal Cortical Malformations Jae Seok Lim and Jeong Ho Lee
16. Using Fluorescence In Situ Hybridization (FISH) Analysis to Measure Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative Diseases Julbert Caneus, Antoneta Granic, Heidi J. Chial, Huntington Potter
17. Identification of Low Allele Frequency Mosaic Mutations in Alzheimer Disease Carlo Sala Frigerio, Mark Fiers, Thierry Voet, and Bart De Strooper
Автор: Rudolf Jaenisch; Feng Zhang; Fred Gage Название: Genome Editing in Neurosciences ISBN: 3319601911 ISBN-13(EAN): 9783319601915 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is open access under a CC BY 4.0 license.
CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease.
This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of development and function in the nervous system, uncovering the molecular causes of neurological disorders and providing tools for gene therapy.
Описание: This volume is based on a meeting of the Fondation IPSEN, held in Paris on Sep- tember 18, 1995 to address the main issues of nervous system stem cells biology. Cell replacement in the adult mammals is not unusual outside the nervous sys- tem. In fact, the nervous system is unique in lacking the ability to replace cells, following damage. Most neurons, in the adult central nervous system are termin- of the organism and are not replaced ally differentiated, exist through the life when they die. There are, however, regions of the postnatal brain that continue to produce new neurons, but the fate and longevity of those cells are not well known. Evidence exists that small populations of neurons continue to be born in the adult ventricular zone, olfactory epithelium and hippocampus. In the adult hippocampus, newly born neurons originate from putative stem cells that exist in the sub granular zone of the dentate gyrus. Progeny of these putative stem cells differentiate into neurons in the granular layer within a month of the cells' birth, and this late neurogenesis continues throughout the adult life of the rodent. By understanding the nature of progenitor cells present in the embryonic and adult brains, the change in their population dynamics during development, and the factors that influence their proliferation, fate choice and differentiation, it may be possible to develop a strategy to manipulate cells in situ to treat neuro- degenerative diseases or the injured adult brain.
Автор: R.L. Hannah; S.E. Reed Название: Strain Gage Users` Handbook ISBN: 0412537206 ISBN-13(EAN): 9780412537202 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A resource for those entering the field of stress analysis and instrumentation.
Описание: This practical, yet inspirational book combines timeless principles of wealth-building and success with no-nonsense guidance on how to succeed in today`s complex, competitive world. Brash, thought provoking, and always entertaining, Randy Gage explores all the issues that affect personal health, happiness, and prosperity.
Автор: McWeeny Gage Название: The Comfort of Strangers: Social Life and Literary Form ISBN: 019979720X ISBN-13(EAN): 9780199797202 Издательство: Oxford Academ Рейтинг: Цена: 12989.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In most accounts, literature of the nineteenth century compulsively tells the story of the individual and interiority. But amidst the newly dense social landscapes of modernity, with London as the first city of one million inhabitants, this literature also sought to represent those unknown and unmet: strangers. Focusing on the ways that both Victorian literature and modern social thought responded to an emergent "society of strangers," The Comfort of Strangers argues for a new relation between literary form and the socially dense environments of modernity, insisting upon strangers in these works not as alienating, fearsome others, but a relatively banal yet transformative fact of everyday life, the dark matter of the nineteenth-century social universe. Taking up "the literature of social density," Gage McWeeny engages with a range of generically diverse works from the age of Victorian sympathy to illuminate surprising investments in ephemeral relations, anonymity, and social distance. Life amidst strangers on urban streets and markets produced new social experiences, both alluring and fearsome, and McWeeny shows how realist literary form is remade by the relational possibilities offered by the impersonal intimacy of life among those unknown and the power of weak social ties. Reading works by Charles Dickens, Matthew Arnold, George Eliot, Oscar Wilde, and Henry James, he discovers a species of Victorian sociality not imagined under J.S. Mill's description in On Liberty of society as a crowd impinging upon the individual. Instead, McWeeny mines nineteenth-century literature's sociological imagination to reveal a set of works diverted by and into intensities located in strangers and the modern forms of sociality they emblematize. Treating seriously the preference for the many over the few, the impersonal intimacy of strangers over those who are friends and acquaintances, The Comfort of Strangers shows how literature and sociology together produced modern understandings of the social, opening up canonical works of the nineteenth century to a host of strange, new meanings.
Описание: The only book to deal specifically with the treatment of gait problems in cerebral palsy, this comprehensive, multi-disciplinary volume will be invaluable for all those working in the field of cerebral palsy and gait (neurologists, therapists, physiatrists, orthopaedic and neurosurgeons, and bioengineers). The book is divided into two parts.
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