Transcriptome Data Analysis, Wang

Автор: Yejun Wang; Ming-an Sun
Название: Transcriptome Data Analysis
ISBN: 1493992643 ISBN-13(EAN): 9781493992645
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Поставка под заказ.

Описание: This detailed volume provides comprehensive practical guidance on transcriptome data analysis for a variety of scientific purposes. Beginning with general protocols, the collection moves on to explore protocols for gene characterization analysis with RNA-seq data as well as protocols on several new applications of transcriptome studies.  Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Автор: Passos Geraldo A.
Название: Thymus Transcriptome and Cell Biology
ISBN: 3030120392 ISBN-13(EAN): 9783030120399
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Поставка под заказ.

Описание: This volume focuses on challenging field in biomedicine that is the genetic control of central immune tolerance. It covers the thymus development, their cellular components and their respective function, the peculiar gene expression profiling (transcriptome) found in the medullary thymic epithelial cells (mTECs) that are implicated in the self-representation in the thymus, the Autoimmune regulator (Aire) gene, the mutations in this gene and manifestation of autoimmune diseases, and the role of cell-cell interactions within the thymus with implications in the negative selection (elimination) of nascent autoreactive T cells in preventing aggressive autoimmunity. The thymus gland is a lymphoid organ implicated in the maturation, differentiation and selection of T cells. This organ is gained more and more attention in different biomedical research labs worldwide due to its function that is associated with the control of immune homeostasis in the body, establishing the central immune tolerance and preventing the onset of autoimmune diseases.