Transcriptome Data Analysis, Yejun Wang; Ming-an Sun

Автор: Wang
Название: Transcriptome Data Analysis
ISBN: 1493977091 ISBN-13(EAN): 9781493977093
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This detailed volume provides comprehensive practical guidance on transcriptome data analysis for a variety of scientific purposes. Beginning with general protocols, the collection moves on to explore protocols for gene characterization analysis with RNA-seq data as well as protocols on several new applications of transcriptome studies.  Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Автор: Passos Geraldo A.
Название: Thymus Transcriptome and Cell Biology
ISBN: 3030120422 ISBN-13(EAN): 9783030120429
Издательство: Springer
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Цена: 20962.00 р.
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Описание: 1. History of the thymus: From a vestigial organ to the programming of immunological self-tolerance.- 2. Thymus Ontogeny and Development.- 3. The Ins and Outs of Thymic Epithelial Cell Differentiation and Function.- 4. T-Cell Development: From T-Lineage Specification to Intrathymic Maturation.- 5. Intrathymic cell migration: implications in thymocyte development and T-cell repertoire formation.- 6. Thymic crosstalk: an overview of the complex cellular interactions that control the establishment of T-cell tolerance.- 7. The Autoimmune Regulator (AIRE) gene, the master activator of self-antigen expression in the thymus.- 8. Aire Mutations and Autoimmune Diseases.- 9. The thymus as a mirror of the body's gene expression.- 10. Functional genomics of the infant human thymus: Aire and minipuberty.- 11. Thymus transcriptome of TGF-β superfamily.- 12. Development of thymic regulatory T lymphocytes.- 13. Adding insult to injury: improving the regenerative capacity of the aged thymus following clinically induced damage.- 14. Thymus rejuvenation after autologous hematopoietic stem cell transplantation in patients with autoimmune diseases.