Автор: John Playfair and Gregory Bancroft Название: Infection & Immunity Fourth Edition ISBN: 0199609500 ISBN-13(EAN): 9780199609505 Издательство: Oxford Academ Рейтинг: Цена: 9027.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gives a perfectly balanced overview of the field, describing the key infectious agents our bodies encounter and how our immune system responds to them. It also explains how diseases are spread and what measures we can take to control this spread, from vaccination to increasing public awareness.
Автор: Bryan R. Cullen Название: Intrinsic Immunity ISBN: 3642427634 ISBN-13(EAN): 9783642427633 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted.
Автор: Kufer Название: Effector-Triggered Immunity ISBN: 1071624482 ISBN-13(EAN): 9781071624487 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume presents a collection of protocols to study effector-triggered immunity (ETI) in both plants and animals from eminent groups in the field. The chapters in this book cover topics such as genetic manipulation of plant and animal pathogens, host cells, and the analysis of key host responses; and techniques used for the analysis of inflammasome activation, cell death pathways, and mitochondria damage in response to pathogens. All of these topics cover a broad spectrum of immunological, biochemical, cell biological, and structural biology approaches to examine ETI. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Effector-Triggered Immunity: Methods and Protocols is a valuable resource for both expert and novice researchers who are interested in learning more about the important and developing field of ETI.
Автор: Yamasaki Название: C-Type Lectin Receptors in Immunity ISBN: 4431567534 ISBN-13(EAN): 9784431567530 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists.
Автор: R. Lee Reinhardt Название: Type 2 Immunity ISBN: 1493993186 ISBN-13(EAN): 9781493993185 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Поставка под заказ.
Описание: This book provides researchers the opportunity to investigate type-2-associated diseases in their laboratories. Beginning with chapters describing various models of type-2 immunity, the volume then continues by detailing cellular protocols designed to identify, characterize, and assess the function of key adaptive and innate immune cells involved in type-2 inflammation; approaches to isolate and evaluate specific cellular subsets at the genetic, epigenetic, and molecular level; protocols to assess type-2 immunity and its relationship to organismal and metabolic systems (ex. Microbiome). This book concludes with a section that explores the use of primary human cells in evaluating relevance to the clinic. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Vital and authoritative, Type 2 Immunity: Methods and Protocols aims to provide a broad network of methods that can be used to develop a hypothesis and investigate its potential from bench to beside.
Описание: Ulrich Desselberger, Gif-sur-Yvette/Cambridge.Infection of a naive (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity).
Автор: Carroll, Patrick Название: State of immunity ISBN: 0520247493 ISBN-13(EAN): 9780520247499 Издательство: Wiley Рейтинг: Цена: 11246.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A comprehensive history of the social and political aspects of vaccination in the United States, this work tells the story of how vaccination became a widely accepted public health measure over the course of the twentieth century. It examines the strategies that health officials have used to gain public acceptance of vaccines.
Автор: Koji Yasutomo Название: Notch Signaling ISBN: 9811352801 ISBN-13(EAN): 9789811352805 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: Also, the studies regarding the functions of Notch in immune cells and tumor cells have motivated researchers and pharmaceutical companies to develop drugs for treating immune-mediated diseases and tumors.
Автор: Richard Bucala; J?rgen Bernhagen Название: MIF Family Cytokines in Innate Immunity and Homeostasis ISBN: 3319848828 ISBN-13(EAN): 9783319848822 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Поставка под заказ.
Описание: The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established.
Автор: Karen Mossman Название: Innate Antiviral Immunity ISBN: 1493984268 ISBN-13(EAN): 9781493984268 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Поставка под заказ.
Описание: This book explores methods to study the complex and evolving interplay between a virus and its host that range from model systems to the detection of chemical molecules.
Автор: Wang Ji-Yang Название: B Cells in Immunity and Tolerance ISBN: 9811535345 ISBN-13(EAN): 9789811535345 Издательство: Springer Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
Автор: Holger Heine Название: Innate Immunity of Plants, Animals and Humans ISBN: 3662518082 ISBN-13(EAN): 9783662518083 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: All living organisms are in a constant battle against their environment. Since uncontained microorganisms would simply overgrow all higher animals, the evolution of multicellular organisms required adequate and efficient defense mechanisms to protect their own integrity and to ensure their own survival. These defense mechanisms, encompassing receptor proteins that sense the presence of pathogens and effector molecules that are involved in controlling them, are the elemental parts of the innate immune system. For many species, the innate immune system is the sole active defense system. Long thought to be an unspecific immune response, the discovery of the Toll-like receptors and their ligands finally revealed just how specific the innate immune response actually is. This book wants to give an overview of our current knowledge about the innate immune system of plants, animals and humans. It not only covers the innate immune mechanisms and responses of so diverse organisms such as plants, Cnidaria, Drosophila, urochordates and zebrafish, but also the major receptor systems in mammalians and humans as well as the central defense mechanisms, antimicrobial peptides and the complement system.
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