This title includes a number of Open Access chapters.
This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including:
host-pathogen interactions
causal relationships between genes and the environment
the effects of environmental chemicals on gene expression
DNA methylation
The book also covers the analysis and provides models for understanding the epigenetics-pathology connection.
This book is designed for use by senior undergraduate and graduate students from several disciplines such as general, molecular, cellular biology, genetics, genomics, proteomics, and bioinformatics. It will also serve as a reference book for existing researchers and new investigators entering this rather unexplored field.
Автор: Nickerson Название: Molecular Paradigms of Infectious Disease ISBN: 1441940421 ISBN-13(EAN): 9781441940421 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides an overview of host genetic factors that provide complete or partial resistance to infection, that influence the clinical outcome of infection, or that confer the capacity to remain healthy during infection.
Автор: Pierce Benjamin A Название: Genetics Essentials. Concepts and Connections. - 3th ed. ISBN: 1464190755 ISBN-13(EAN): 9781464190759 Издательство: Springer Рейтинг: Цена: 9083.00 р. Наличие на складе: Поставка под заказ.
Описание: Derived from Ben Pierce's popular and acclaimed Genetics: A Conceptual Approach, this streamlined text covers basic transmission, molecular, and population genetics.
Автор: Christon J. Hurst Название: Modeling the Transmission and Prevention of Infectious Disease ISBN: 331960614X ISBN-13(EAN): 9783319606149 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preventing infectious diseases in spacecraft and space habitats.- Bacterial resistance to hospital disinfection.- Disinfection of microbial aerosols.- The role of the indigenous gut microbiota in human health and disease.- Buruli ulcer: Case Study of a Neglected Tropical Disease.- Coccidioidomycosis: increasing incidence of an 'orphan' disease in response to environmental changes.- Antibiotic resistant environmental bacteria and their role as reservoirs in disease.- Population dynamics, invasion and biological control of environmentally growing opportunistic pathogens.- Of ducks and men - ecology and evolution of a zoonotic pathogen in a wild reservoir host.
Автор: Vitali Sintchenko Название: Infectious Disease Informatics ISBN: 1489982957 ISBN-13(EAN): 9781489982957 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers breakthroughs in the rapid, high-throughput molecular profiling of pathogenic microorganisms, as well as text mining. There is focus on bioinformatics enabled approaches to pathogen detection, investigation and management of infections.
Автор: Wayne Marta Название: Infectious Disease: A Very Short Introduction ISBN: 0199688931 ISBN-13(EAN): 9780199688937 Издательство: Oxford Academ Рейтинг: Цена: 1792.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this Very Short Introduction Benjamin Bolker and Marta L. Wayne explore the world of infectious disease, from viruses and bacteria to protists and fungi. Taking an ecological and evolutionary viewpoint, they use case studies to explore how outbreaks are managed and how newly emergent strains might be controlled.
Автор: Janos Minarovits; Hans Helmut Niller Название: Patho-Epigenetics of Infectious Disease ISBN: 3319247360 ISBN-13(EAN): 9783319247366 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization. The present volume undertakes to highlight the interactions of infectious pathogens and their effector molecules with the epigenetic regulatory machinery of the cell. Clearly, the recent take-off of epigenetics research did not leave Research on Infectious Diseases and Infection-Associated Cancer untouched. This resulted in a great many of clinically relevant data on understanding the molecular mechanisms of chronic infectious disease. Infectious pathogen- and disease-specific epigenetic alterations are already being used for the early detection of malignant disease and for the prediction of chemotherapy resistance or response to treatment.
Автор: Ewald, Paul W. Название: Evolution of Infectious Disease (Hardback) ISBN: 019506058X ISBN-13(EAN): 9780195060584 Издательство: Oxford Academ Рейтинг: Цена: 36036.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aimed at evolutionary biologists, ecologists and epidemiologists, this extended essay presents an evolutionary-biological perspective of human infectious disease.
Автор: Bradley T. Hyman; Charles Duyckaerts Название: Connections, Cognition and Alzheimer`s Disease ISBN: 3642645046 ISBN-13(EAN): 9783642645044 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Michel Tibayreng Название: Genetics and Evolution of Infectious Diseases, 2 ed. ISBN: 0127999426 ISBN-13(EAN): 9780127999425 Издательство: Elsevier Science Рейтинг: Цена: 22233.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. . Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. . The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses.
Автор: Austin Brian, Austin B. Название: Infectious Disease in Aquaculture: Prevention and Control ISBN: 0081016336 ISBN-13(EAN): 9780081016336 Издательство: Elsevier Science Рейтинг: Цена: 32844.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With an ever increasing demand for seafood that cannot be met by capture fisheries alone, growing pressure is being placed on aquaculture production. However, infectious diseases are a major constraint. Infectious disease in aquaculture: prevention and control brings together a wealth of recent research on this problem and its effective management.Part one considers the innate and adaptive immune responses seen in fish and shellfish together with the implications of these responses for disease control. The specific immune response of molluscs and crustaceans is considered in depth, along with the role of stress in resistance to infection. Advances in disease diagnostics, veterinary drugs and vaccines are discussed in part two, with quality assurance, the use and effects of antibiotics and anti-parasitic drugs in aquaculture, and developments in vaccination against fish are explored. Part three focuses on the development of specific pathogen-free populations and novel approaches for disease control. Specific pathogen free shrimp stocks, developments in genomics and the use of bacteria and bacteriophages as biological agents for disease control are explored, before the management and use of natural antimicrobial compounds.With its distinguished editor and expert team of contributors, Infectious disease in aquaculture: prevention and control provides managers of aquaculture facilities and scientists working on disease in aquaculture with a comprehensive and systematic overview of essential research in the prevention and control of infectious disease.
Автор: Fullick William Название: Human Infectious Disease and Public Health ISBN: 0198814380 ISBN-13(EAN): 9780198814382 Издательство: Oxford Education Рейтинг: Цена: 5542.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Infectious disease will affect most of us at some point in our lives, despite tremendous advances in medicine over the past century. We all still fall ill from pathogens in our everyday environments - but many of us now survive infections which would have proved fatal in the past. Our understanding of the nature of infectious diseases continues to grow - as does our understanding of the human immune system. We continue to develop drugs and public health regimens to attempt to treat or prevent more and more diseases from causing acute sickness and/or long-term health problems - and indeed, we have been successful at eradicating (or almost eradicating) a number of previously common illnesses over the past fifty years. This text explores the structure and function of each distinct type of pathogen (bacteria, viruses, fungi, parasites and prion disease), as well as the biochemical processes taking place when an infection is caused by any of these agents. It goes on to look at the role the human immune system plays in preventing, containing and destroying pathogens which enter the human body, using up to date research to ensure that students are abreast of the most recent developments in immunology. The text also examines the "evolutionary arms race" between human beings and infectious disease, looking at genetic traits which confer protection against some infectious diseases, and how pathogens are constantly changing to work around our defences. The final section of the primer explores disease prevention and treatment - antibiotics, antivirals and antifungal agents and their mechanisms of action; public health and vaccination; the dangers of antibiotic resistance; and potential sources for new antimicrobial agents around the world. Online resources For students: [TBC] For teachers: Artwork from the book in easy-to-download format, for use in class materials and handouts
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