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Total Synthesis of Natural Products with Antimicrobial Activity, Giltrap


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Цена: 18167.00р.
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Автор: Giltrap
Название:  Total Synthesis of Natural Products with Antimicrobial Activity
ISBN: 9789811088056
Издательство: Springer
Классификация:

ISBN-10: 9811088055
Обложка/Формат: Hardcover
Страницы: 268
Вес: 0.60 кг.
Дата издания: 2018
Серия: Springer Theses
Язык: English
Издание: 1st ed. 2018
Иллюстрации: 59 illustrations, color; 85 illustrations, black and white; xxiv, 268 p. 144 illus., 59 illus. in color.
Размер: 234 x 156 x 18
Читательская аудитория: Professional & vocational
Основная тема: Medicinal Chemistry
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This thesis focuses on the development of efficient and scalable total syntheses of natural products that can be used as preferred scaffolds for anti-infective drug discovery. It describes the total synthesis of two classes of antimicrobial non-ribosomal peptides (NRPs) – teixobactin and the skyllamycins – with subsequent biological evaluation. The first part describes the first total synthesis of teixobactin by means of a solid-phase peptide synthesis-macrolactamisation approach, yielding a synthetic natural product that can combat a number of clinically relevant Gram-positive bacterial pathogens. The second part describes the first total synthesis of skyllamycins A-C, a family of structurally complex cyclic NRPs, which inhibit the growth of the Pseudomonas aeruginosa biofilms that are responsible for significant mortality among cystic fibrosis patients.
Дополнительное описание: Introduction.- Total Synthesis of Teixobactin.- Synthesis of Deshydroxy Skyllamycins A-C.- Total Synthesis of Skyllamycins A-C.- Experimental.



Meyler`s Side Effects of Antimicrobial Drugs,

Автор: Jeffrey K. Aronson
Название: Meyler`s Side Effects of Antimicrobial Drugs,
ISBN: 0444532722 ISBN-13(EAN): 9780444532725
Издательство: Elsevier Science
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Цена: 8420.00 р.
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Описание: Suitable for internal medicine physicians and general practitioners who prescribe antibiotic drugs, like penicillin and tetracycline that cure bacterial infections, and antiviral drugs used to treat patients with HIV and herpes viruses.

Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton (
Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
ISBN: 0387756124 ISBN-13(EAN): 9780387756127
Издательство: Springer
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Цена: 23757.00 р.
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Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Essentials of Antimicrobial Pharmacology / A Guide to Fundamentals for Practice

Автор: Axelsen Paul H.
Название: Essentials of Antimicrobial Pharmacology / A Guide to Fundamentals for Practice
ISBN: 0896037606 ISBN-13(EAN): 9780896037601
Издательство: Springer
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Цена: 15672.00 р.
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Описание: Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. This book provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.

Novel Antimicrobial Agents and Strategies

Автор: David A. Phoenix,
Название: Novel Antimicrobial Agents and Strategies
ISBN: 3527336389 ISBN-13(EAN): 9783527336388
Издательство: Wiley
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Цена: 25336.00 р.
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Описание: A complete survey of current and future antimicrobial drugs and therapies, from small-molecule antibiotics to antimicrobial peptides and their engineered mimetics, from enzymes to nucleic acid therapeutics, and from metallic nanoparticles to photo- and sonosensitizers.

Antimicrobial Pharmacodynamics

Автор: Nightingale Charles H
Название: Antimicrobial Pharmacodynamics
ISBN: 0824729250 ISBN-13(EAN): 9780824729257
Издательство: Taylor&Francis
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Цена: 33686.00 р.
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Описание: Antimicrobial Pharmacodynamics in Theory and Clinical Practice

Antimicrobial therapeutics reviews

Название: Antimicrobial therapeutics reviews
ISBN: 1573317888 ISBN-13(EAN): 9781573317887
Издательство: Wiley
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Цена: 14810.00 р.
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Описание: This is the inaugural volume in a new series of reviews. Each annual volume will contain authoritative reviews of developing research topics in antimicrobial therapeutics. Authors will describe how the research being reviewed can be applied to real-world problems.

Antimicrobial Chemotherapy

Автор: Finch, Roger; Davey, Peter; Wilcox, Mark H.; Irvin
Название: Antimicrobial Chemotherapy
ISBN: 0199697655 ISBN-13(EAN): 9780199697656
Издательство: Oxford Academ
Цена: 6334.00 р.
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Описание: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the ne

Antimicrobial Chemotherapy 5/e P. 2007

Автор: Greenwood
Название: Antimicrobial Chemotherapy 5/e P. 2007
ISBN: 0198570163 ISBN-13(EAN): 9780198570165
Издательство: Oxford Academ
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Цена: 6328.00 р.
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Описание: Aims to encourage good prescribing habits in doctors throughout the world, by describing the basic properties of antibiotics and other antimicrobial agents, and discussing the principles underlying the rational use of antimicrobial agents in the management of infection.

Biochemistry of Antimicrobial Action

Автор: T. J. Franklin
Название: Biochemistry of Antimicrobial Action
ISBN: 9401068577 ISBN-13(EAN): 9789401068574
Издательство: Springer
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Цена: 12157.00 р.
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Описание: The rapid advances made in the study of the synthesis, structure and function of biological macromolecules in the last fifteen years have enabled scientists concerned with antimicrobial agents to achieve a considerable measure of understanding of how these substances inhibit cell growth and division.


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