Описание: Proceedings of an International Symposium held in New Orleans, Louisiana, October 28, 1997
Автор: Michael S. Wolfe Название: Alzheimer`s Disease II ISBN: 3319594591 ISBN-13(EAN): 9783319594590 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors
Автор: Francois Boller; Robert Katzman; Andre Rascol; Jea Название: Biological Markers of Alzheimer`s Disease ISBN: 3642466923 ISBN-13(EAN): 9783642466922 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The series started in September 1987 with "Im- munology and Alzheimer`s Disease," followed 6 months later in Paris by "Gene- tics and Alzheimer`s Disease" and in September 1988 in Montpellier by "Neuronal Grafting and Alzheimer`s Disease.
Автор: F.H. Gage; A. Privat Название: Neuronal Grafting and Alzheimer`s Disease ISBN: 3642483712 ISBN-13(EAN): 9783642483714 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An answer to the question, whether neuronal grafting will be useful as a therapy for Alzheimer`s disease, must wait for a better understanding of the disease and the identification of animal models that can be used to test potential therapies.
Environmental Causes for Alzheimer's Disease and Prevention Measures examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers.
Emphasizes the history and epidemiology of Alzheimer's disease, highlighting its epidemic proportions in developed countries
Discusses data on new environmental factors in developed countries
Provides prevention measures to potentially reduce Alzheimer's rates through diet
Автор: Taher Zandi; Richard J. Ham Название: New Directions in Understanding Dementia and Alzheimer`s Disease ISBN: 1461279178 ISBN-13(EAN): 9781461279174 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a conference held in Plattsburgh, New York, May 25--26, 1989
Автор: A.D. Roses; K.H. Weisgraber; Y. Christen Название: Apolipoprotein E and Alzheimer`s Disease ISBN: 3642801110 ISBN-13(EAN): 9783642801112 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late- onset Alzheimer's disease, the common form of the disease defined as starting after 60 years of age. The roles of apolipoprotein E in normal brain metabo- lism and in the pathogenesis of Alzheimer's disease are new and exciting avenues of research. This is why the Fondation Ipsen organised an interna- tional meeting on this topic in Paris on May 29,1995, and the proceedings are contained in this book. The editors wish to thank Mrs Mary Lynn Gage for editorial and Mrs Jacqueline Mervaillie for the organization of the meeting in Paris. Allen Roses Karl Weisgraber Yves Christen Contents Apolipoprotein E and Alzheimer's Disease: State of the Field After Two Years A. D. Roses, W. I. Strittmatter, A. M. Saunders, D. E. Schmechel, and M. A. Pericak-Vance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Role of Apolipoprotein E in Alzheimer's Disease: Clues from its Structure KH. Weisgraber and L. M Dong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Apolipoprotein E4, Cholinergic Integrity, Synaptic Plasticity and Alzheimer's Disease I. Poirier, M-C. Delisle, R. Quirion, I. Aubert, I. Rocheford, I. Rousse, S. Gracon, M. Farlow, and S. Gauthier. . . . . . . . . . . . . . . . . . . 20 Pattern of Apolipoprotein E Immunoreactivity During Brain Aging D. E. Schmechel, MO. Tiller, P. Tong, M McSwain, S. -H. Han, R. Ange, D. S. Burkhart, and MK Izard. . . . . . . . . . . . . . . . . . . . . . . . . . .
Описание: Dementia of Alzheimer type (DAT), multiinfarct dementia (MID) and dementia occurring in the course of Parkinson's disease (PD +D) now make up one of the largest categories of chronic diseases in the elderly. In addition to the burden those illnesses impose on the affected individuals and their families they consume large socio-economic re- sources. In the light of all the above mentioned features, it seemed to us that a Symposium on behalf of the 125th Anniversary of Birth of Aloys Alzheimer was particularly well-suited to help to advance research on Alzheimer's disease and other dementias. This International Symposium combined with a Satellite Symposium about "Clinical Aspects of Alz- heimer Dementias" took place in June 1989 in Wiirzburg and has been organized by the Psychiatric Departments of the Universities of Wiirzburg and Munich (H. Beckmann, K. Maurer, P. Riederer, H. Hippius and H. Lauter) and the Department of Pathochemistry and General Neurochemistry of the University of Heidelberg (S. Hoyer). In the chapters which follow, thorough reviews of recognized authorities in the field of dementia are given in the four main fields of epidemiology, neuropathology, neurochemistry and clinics. This Symposium and the edition of this book would not have been possible without the generous support of E. Merck, Darmstadt. In particular we gratefully acknowledge the efforts undertaken by Mr. Hernandez-Meyer to organizing this symposium and to publish this book. Furthermore we are grateful to the secretarial help by Mrs. Moeslein, Miss Philipp and Miss Grabner.
Автор: G?rard Emilien; C?cile Durlach; Kenneth L. Minaker Название: Alzheimer Disease ISBN: 3034895917 ISBN-13(EAN): 9783034895910 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Alzheimer disease (AD) has become the most common form of dementia in industrialized countries and represents an increasing burden at the economic, social and medical level.
Автор: Franz Hefti; Philippe Brachet; Bruno Will Название: Growth Factors and Alzheimer`s Disease ISBN: 3642467245 ISBN-13(EAN): 9783642467240 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Richard Mayeux Название: Epidemiology of Alzheimer`s Disease: From Gene to Prevention ISBN: 3642642454 ISBN-13(EAN): 9783642642456 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Stanley I. Rapoport; Henri Petit; Didier Leys Название: Imaging, Cerebral Topography and Alzheimer`s Disease ISBN: 3642756921 ISBN-13(EAN): 9783642756924 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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