Mapping the Progress of Alzheimer`s and Parkinson`s Disease, Yoshikuni Mizuno; Abraham Fisher; Israel Hanin

Автор: de la Torre
Название: Alzheimer`s Turning Point
ISBN: 3319340565 ISBN-13(EAN): 9783319340562
Издательство: Springer
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Цена: 12577.00 р.
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Описание: This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.

Автор: Derreumaux Philippe
Название: Alzheimer`s Disease: Insights into Low Molecular Weight and
ISBN: 1848167547 ISBN-13(EAN): 9781848167544
Издательство: World Scientific Publishing
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Цена: 22968.00 р.
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Описание: Alzheimer`s disease is the most common form of senile dementia, affecting more than 24 million people worldwide. This book provides a panoramic view across in vitro and in vivo studies along with computer simulations, designed to increase the readers` understanding of oligomerisation and fibril formation.

Автор: Bradley T. Hyman; Jean-Francois Demonet
Название: The Living Brain and Alzheimer`s Disease
ISBN: 3642639275 ISBN-13(EAN): 9783642639272
Издательство: Springer
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Цена: 16979.00 р.
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Описание: From large cross-sectional studies of autopsy material, it seems as if a time course of Alzheimer`s Disease, at least on average, can be mapped out: a pattern of hierarchical vulnerability for neuronal loss and neurofibrillary tangles beginning in medial temporal lobe structures proceeding through association areas.

Автор: Farooqui, Akhlaq A.
Название: Neurochemical Aspects of Alzheimer Disease
ISBN: 0128099372 ISBN-13(EAN): 9780128099377
Издательство: Elsevier Science
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Цена: 13298.00 р.
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Описание:

Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists, and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders.

Автор: Steven G. Younkin; Rudolph E. Tanzi
Название: Presenilins and Alzheimer`s Disease
ISBN: 3642721052 ISBN-13(EAN): 9783642721052
Издательство: Springer
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Цена: 19591.00 р.
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Описание: The role of the familial Alzheimer`s Disease genes called "presenilins" in causing neuronal cell death and Alzheimer-related pathology.

Автор: Mathias Jucker; Konrad Beyreuther; Christian Haass
Название: Alzheimer: 100 Years and Beyond
ISBN: 3642072321 ISBN-13(EAN): 9783642072321
Издательство: Springer
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Цена: 36570.00 р.
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Описание:

Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tubingen.

The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiation of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, was the highlight of the Year of Alzheimer. However, beyond these few months of tributes, the centennial offers a unique opportunity to assess both the progress achieved and the uncertainties remaining. This volume, a collection comprised mainly of articles by the invited speakers and also of a few other prominent researchers, is meant to be a record of those events.

Автор: Bradley T. Hyman; Charles Duyckaerts
Название: Connections, Cognition and Alzheimer`s Disease
ISBN: 3642645046 ISBN-13(EAN): 9783642645044
Издательство: Springer
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Цена: 16979.00 р.
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Автор: Ken S. Kosik; Dennis J. Selkoe
Название: Alzheimer`s Disease: Lessons from Cell Biology
ISBN: 3642794254 ISBN-13(EAN): 9783642794254
Издательство: Springer
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Цена: 20896.00 р.
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Описание: Like the unflinching gaze of Captain Ahab walking the deck of the Pequod, Alzheimer researchers have had their sights fixed firmly on the disease for many years. Perhaps for most of the years since the first descriptions of the disease in 1907, the science of Alzheimer`s disease was descriptive, and lay in the province of pathologists.