Автор: DOUDNA & MALI Название: CRISPR-Cas : ISBN: 1621821315 ISBN-13(EAN): 9781621821311 Издательство: NBN International Рейтинг: Цена: 18216.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The development of CRISPR-Cas technology is revolutionizing biology. Based on machinery bacteria use to target foreign nucleic acids, these powerful techniques allow investigators to edit nucleic acids and modulate gene expression more rapidly and accurately than ever before. Featuring contributions from leading figures in the CRISPR-Cas field, this laboratory manual presents a state-of-the-art guide to the technology. It includes step-by-step protocols for applying CRISPR-Cas-based techniques in various systems, including yeast, zebrafish, Drosophila, mice, and cultured cells (e.g., human pluripotent stem cells). The contributors cover web-based tools and approaches for designing guide RNAs that precisely target genes of interest, methods for preparing and delivering CRISPR-Cas reagents into cells, and ways to screen for cells that harbor the desired genetic changes. Strategies for optimizing CRISPR-Cas in each system--especially for minimizing off-target effects--are also provided. Authors also describe other applications of the CRISPR-Cas system, including its use for regulating genome activation and repression, and discuss the development of next-generation CRISPR-Cas tools. The book is thus an essential laboratory resource for all cell, molecular, and developmental biologists, as well as biochemists, geneticists, and all who seek to expand their biotechnology toolkits.
CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present and future of CRISPR genome editing. Topics of interest in this updated volume include a section on CRISPR history, The genome editing revolution, Programming CRISPR and its applications, CRISPR Delivery methods, CRISPR libraries and screening, CRISPR investigation in haploid cells, CRISPR in the generation of transgenic animals, CRISPR therapeutics, and Promising strategies and present challenges.
Автор: Casem, Merri Lynn Название: Case Studies in Cell Biology ISBN: 012801394X ISBN-13(EAN): 9780128013946 Издательство: Elsevier Science Рейтинг: Цена: 9936.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: . Case Studies in Cell Biology presents real world scenarios to help readers use science process and reasoning skills. The case studies require application and analyzation of concepts beyond rote memory of biological concepts. The book is based on the student learning outcomes from the American Society for Cell Biology, offering practical application for both the classroom and research laboratory.
Автор: B. Casu; J. Harenberg Название: Nonanticoagulant Actions of Glycosaminoglycans ISBN: 1461380219 ISBN-13(EAN): 9781461380214 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aim of the Fourth Symposium on Glycosaminoglycan Research at Villa Vigoni in Loveno at Lake Comolltaly was to summarize the considerable new information in this field. New methods for their identification and assays are described and considerable emphasis is placed on the pharmacokinetic aspects of these new compounds.
Автор: Miguel Valc?rcel Cases; ?ngela I. L?pez-Lorente; M Название: Foundations of Analytical Chemistry ISBN: 3319874160 ISBN-13(EAN): 9783319874166 Издательство: Springer Рейтинг: Цена: 9083.00 р. Наличие на складе: Поставка под заказ.
Описание: This book offers a completely new approach to learning and teaching the fundamentals of analytical chemistry. It summarizes 250 basic concepts of the field on the basis of slides. Each of the nine chapters offers the following features:• Introduction: Summary. General scheme. Teaching objectives.• Text containing the explanation of each slide.• Recommended and commented bibliography.• Questions to be answered.• Slides. A distinct feature of this novel book is its focus on the fundamental concepts and essential principles of analytical chemistry, which sets it apart from other books presenting descriptive overviews of methods and techniques.
Автор: Maria D. Luque de Castro; Miguel Valcarcel; Maria Название: Analytical Supercritical Fluid Extraction ISBN: 3642786758 ISBN-13(EAN): 9783642786754 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent advances in analytical chemistry have turned it into a virtually unrecognizable science compared to a few decades ago, when it lagged behind other sciences and techniques. However, advances in analytical science have been far from universal: while innovations in instrumentation and data acquisition and processing systems have reached unprecedented levels thanks to parallel breakthroughs in computer science and chemo- metrics, progress in preliminary operations has been much slower despite their importance to analytical results. Thus, such clear trends in analytical process development as automation and miniaturization have not reached preliminary operations to the same extent, even though this area is pro- bably in the greatest need. Improvement in preliminary operations is thus an urgent goal of analytical chemistry on the verge of the twenty first century. Increased R&D endeavours and manufacture of commercially available automatic equipment for implementation of the wide variety of operations that separate the uncollected, unmeasured, untreated sample from the signal measuring step are thus crucial on account of the wide variability of such operations, which precludes development of all-purpose equipment, and the complexity of some, particularly relating to solid samples. Supercritical fluid extraction opens up interesting prospects in this context and is no doubt an effective approach to automatioI1 and mini- aturization in the preliminary steps of the analytical process. The dramatic developments achieved in its short life are atypical in many respects.
Автор: A.F. Casy Название: The Steric Factor in Medicinal Chemistry ISBN: 1489923993 ISBN-13(EAN): 9781489923998 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Valcarcel Cases, Miguel Lopez-lorente, Angela I. Lopez-jimenez, M. Angeles Название: Foundations of analytical chemistry ISBN: 3319628712 ISBN-13(EAN): 9783319628714 Издательство: Springer Рейтинг: Цена: 9083.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This new edition of the best-selling book focuses on various aspects of recruiting, including assessing an institution`s readiness to recruit international students, building human resource capacity for international recruitment, creating an international recruitment plan, recruiting international students from within the United States, measuring return on investment, and more.
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